Brief Information of the Compound and Protein
Compound Name
C-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin-1-yl]-ethyl}-1H-indol-5-yl)-N-methyl-methanesulfonamide
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PubChem ID
CID: 9867902
SID: 15603257
Canonical SMILES
CNS(=O)(=O)Cc1ccc2[nH]cc(CCN3CC[C@@H](CNCc4ccccc4)C3)c2c1
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Compound Formula C24H32N4O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 3.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.1 nM