Brief Information of the Compound and Protein
Compound Name
Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
    Show/Hide
PubChem ID
CID: 11796081
SID: 16909464
Canonical SMILES
C(Cc1c[nH]c2ccc(Cn3cncn3)cc12)N1CC[C@@H](CNCc2ccccc2)C1
    Show/Hide
Compound Formula C25H30N6
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 4.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.2 nM
   TI
   LI
   LO
   TS