Brief Information of the Compound and Protein
Compound Name
N-(furan-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
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PubChem ID
CID: 11795525
SID: 16908885
Canonical SMILES
C(CN1CCC(CC1)NCc1ccoc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1
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Compound Formula C23H28N6O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 7.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 4.5 nM
   TI
   LI
   LO
   TS