Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-{4-[2-(3-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
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 PubChem ID
CID: 6426760
SID: 14930077
Canonical SMILES
Fc1cccc(CCN2CCN(CCCc3c[nH]c4ccc(cc34)-n3cnnc3)CC2)c1
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Compound Formula C25H29FN6
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
4
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.6 nM