Brief Information of the Compound and Protein
Compound Name
(S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-methyl]-pyrrolidin-1-yl}-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one
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PubChem ID
CID: 11797644
SID: 16911068
Canonical SMILES
C[C@H](NC[C@@H]1CCN(CCc2c[nH]c3ccc(C[C@H]4COC(=O)N4)cc23)C1)c1ccccc1
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Compound Formula C27H34N4O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
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Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.3 nM