| Compound ID |
Compound Name |
Compound Formula |
|
CP0175080
|
(4S)-4-amino-5-[[(2S,3R)-1-[(2R)-2-[[(2S)-1-[[(4R,7S,10R,13S,16R,19S)-10-(4-aminobutyl)-16-benzyl-4-[[(1S)-1-carboxy-2-methylpropyl]carbamoyl]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C64H85N13O18S2
|
1
|
| 1 |
EC50 = 1.09 nM
|
|
|
|
CP0406109
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C50H64N10O12S2
|
1
|
| 1 |
EC50 = 1.862 nM
|
|
|
|
CP0134132
|
(4S)-4-amino-5-[[(2S,3R)-1-[(2S)-2-[[(2S)-1-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-16-benzyl-4-[[(1S)-1-carboxy-2-methylpropyl]carbamoyl]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C65H87N13O18S2
|
1
|
| 1 |
EC50 = 2.692 nM
|
|
|
|
CP0148061
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C49H64N10O10S2
|
6
|
| 1 |
EC50 = 2.692 nM
|
|
|
| 2 |
EC50 = 3.631 nM
|
|
|
| 3 |
EC50 = 91.2 nM
|
|
|
| 4 |
EC50 = 144.54 nM
|
|
|
| 5 |
IC50 = 5.129 nM
|
|
|
| 6 |
IC50 = 19.5 nM
|
|
|
|
CP0270410
|
Urotensin-II
Show/Hide
|
C64H85N13O18S2
|
1
|
| 1 |
EC50 = 3.02 nM
|
|
|
|
CP0435159
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-14-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C51H66N10O12S2
|
1
|
| 1 |
EC50 = 3.631 nM
|
|
|
|
CP0134134
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C51H66N10O12S2
|
1
|
| 1 |
EC50 = 4.677 nM
|
|
|
|
CP0225591
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C50H66N10O10S2
|
1
|
| 1 |
EC50 = 5.248 nM
|
|
|
|
CP0469430
|
(4S)-4-amino-5-[[(2S,3R)-1-[(2S)-2-[[(2S)-1-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-16-benzyl-4-[[(1S)-1-carboxy-2-methylpropyl]carbamoyl]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-14-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C65H87N13O18S2
|
1
|
| 1 |
EC50 = 5.623 nM
|
|
|
|
CP0504574
|
(6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-6-benzyl-15-(4-hydroxybenzyl)tetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C42H50N8O7
|
1
|
| 1 |
EC50 = 6.94 nM
|
|
|
|
CP0391857
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-amino-3-carboxypropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-16-[(4-iodophenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C50H63IN10O12S2
|
4
|
| 1 |
EC50 = 7.079 nM
|
|
|
| 2 |
EC50 = 36.31 nM
|
|
|
| 3 |
EC50 = 190.55 nM
|
|
|
| 4 |
IC50 = 3.981 nM
|
|
|
|
CP0415262
|
(6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-15-(4-hydroxybenzyl)-6-(hydroxymethyl)tetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C36H46N8O8
|
1
|
| 1 |
EC50 = 8.51 nM
|
|
|
|
CP0504575
|
(6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-15-benzyl-6-(hydroxymethyl)tetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C36H46N8O7
|
1
|
| 1 |
EC50 = 10.07 nM
|
|
|
|
CP0394373
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-16-[(4-iodophenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C49H63IN10O10S2
|
4
|
| 1 |
EC50 = 10.72 nM
|
|
|
| 2 |
EC50 = 47.86 nM
|
|
|
| 3 |
EC50 = 181.97 nM
|
|
|
| 4 |
IC50 = 5.623 nM
|
|
|
|
CP0401815
|
(6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-6,15-bis(4-hydroxybenzyl)tetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C42H50N8O8
|
1
|
| 1 |
EC50 = 12.58 nM
|
|
|
|
CP0401816
|
(6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-6,15-dibenzyltetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C42H50N8O6
|
1
|
| 1 |
EC50 = 13.2 nM
|
|
|
|
CP0169106
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-14-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C50H66N10O10S2
|
1
|
| 1 |
EC50 = 13.8 nM
|
|
|
|
CP0391855
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-16-[(4-phenylphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C55H68N10O10S2
|
4
|
| 1 |
EC50 = 15.14 nM
|
|
|
| 2 |
EC50 = 120.23 nM
|
|
|
| 3 |
EC50 = 602.56 nM
|
|
|
| 4 |
IC50 = 5.37 nM
|
|
|
|
CP0471741
|
(6S,9S,12S,15S,20aS)-9,15-bis((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-6-(hydroxymethyl)tetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C38H47N9O7
|
1
|
| 1 |
EC50 = 16.72 nM
|
|
|
|
CP0225590
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-amino-3-carboxypropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-17-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C51H66N10O12S2
|
1
|
| 1 |
EC50 = 18.62 nM
|
|
|
|
CP0400072
|
(6S,9S,12S,15S,20aS)-9,15-bis((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-6-benzyltetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C44H51N9O6
|
1
|
| 1 |
EC50 = 20.55 nM
|
|
|
|
CP0169105
|
(4S)-4-amino-5-[[(2S,3R)-1-[(2S)-2-[[(2S)-1-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-16-benzyl-4-[[(1S)-1-carboxy-2-methylpropyl]carbamoyl]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-17-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C65H87N13O18S2
|
1
|
| 1 |
EC50 = 22.39 nM
|
|
|
|
CP0414166
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-16-[[4-(2-phenylethynyl)phenyl]methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C57H68N10O10S2
|
4
|
| 1 |
EC50 = 27.54 nM
|
|
|
| 2 |
EC50 = 147.91 nM
|
|
|
| 3 |
EC50 = 758.58 nM
|
|
|
| 4 |
IC50 = 26.92 nM
|
|
|
|
CP0411223
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-carboxypropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-16-[(4-iodophenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C50H63IN10O12S2
|
4
|
| 1 |
EC50 = 46.77 nM
|
|
|
| 2 |
EC50 = 123.03 nM
|
|
|
| 3 |
EC50 = 346.74 nM
|
|
|
| 4 |
IC50 > 1000 nM
|
|
|
|
CP0391845
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-aminopropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-16-[(4-iodophenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C49H63IN10O10S2
|
4
|
| 1 |
EC50 = 53.7 nM
|
|
|
| 2 |
EC50 = 89.13 nM
|
|
|
| 3 |
EC50 = 354.81 nM
|
|
|
| 4 |
IC50 > 1000 nM
|
|
|
|
CP0518872
|
(6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-(4-aminobutyl)-15-benzyl-6-(4-hydroxybenzyl)tetradecahydropyrrolo[1,2-a][1,4,7,10,13,16]hexaazacyclooctadecine-1,4,7,10,13,16-hexaone
Show/Hide
|
C42H50N8O7
|
1
|
| 1 |
EC50 = 75.66 nM
|
|
|
|
CP0225587
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-17-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C50H66N10O10S2
|
1
|
| 1 |
EC50 = 104.71 nM
|
|
|
|
CP0391856
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-aminopropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-16-[[4-(2-phenylethynyl)phenyl]methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C57H68N10O10S2
|
4
|
| 1 |
EC50 = 380.19 nM
|
|
|
| 2 |
EC50 = 616.6 nM
|
|
|
| 3 |
EC50 = 3311.31 nM
|
|
|
| 4 |
IC50 > 1000 nM
|
|
|
|
CP0393929
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-aminopropanoyl]amino]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-16-[(4-phenylphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C55H68N10O10S2
|
4
|
| 1 |
EC50 = 660.69 nM
|
|
|
| 2 |
EC50 = 1148.15 nM
|
|
|
| 3 |
EC50 = 3548.13 nM
|
|
|
| 4 |
IC50 > 1000 nM
|
|
|
|
CP0569975
|
(2S)-2-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-13-[(4-iodophenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C47H62IN9O10S2
|
1
|
| 1 |
IC50 = 2.455 nM
|
|
|
|
CP0575900
|
(2S)-2-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[(4-phenylphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C53H67N9O10S2
|
1
|
| 1 |
IC50 = 3.162 nM
|
|
|
|
CP0152907
|
(S)-N-(1-(3-bromo-4-(piperidin-4-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H26BrCl2N3O2
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0239321
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3,4-difluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H28ClF2N3O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0564654
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[(4-phenylmethoxyphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C54H69N9O11S2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0445893
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3-fluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H29ClFN3O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0547306
|
(2S)-2-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[[4-(2-phenylethynyl)phenyl]methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C55H67N9O10S2
|
1
|
| 1 |
IC50 = 12.02 nM
|
|
|
|
CP0052641
|
1-[2-[4-[(4-fluorophenyl)methyl]-4-hydroxypiperidin-1-yl]ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C22H25FN4O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0476996
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2-ethylphenyl)furan-2-yl]methanone
Show/Hide
|
C29H34ClN3O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0445765
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2-propan-2-yloxyphenyl)furan-2-yl]methanone
Show/Hide
|
C30H36ClN3O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0445862
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-[2-(trifluoromethyl)phenyl]furan-2-yl]methanone
Show/Hide
|
C28H29ClF3N3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0477132
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3-methoxyphenyl)furan-2-yl]methanone
Show/Hide
|
C28H32ClN3O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0540705
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2,3-difluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H28ClF2N3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0481789
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2-methylphenyl)furan-2-yl]methanone
Show/Hide
|
C28H32ClN3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0484694
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2-ethoxyphenyl)furan-2-yl]methanone
Show/Hide
|
C29H34ClN3O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0463254
|
1-[2-[4-[(2-bromophenyl)methyl]-4-hydroxypiperidin-1-yl]ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C22H25BrN4O2S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0550829
|
1-[2-[4-hydroxy-4-[(2-methylphenyl)methyl]piperidin-1-yl]ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0484695
|
[5-(3-chlorophenyl)furan-2-yl]-[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]methanone
Show/Hide
|
C27H29Cl2N3O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0401964
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2,5-difluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H28ClF2N3O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0466723
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3-phenylphenyl)furan-2-yl]methanone
Show/Hide
|
C33H34ClN3O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0188219
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-cyano-1-benzothiophene-2-carboxamide
Show/Hide
|
C27H29BrN4O2S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0536636
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(5-methylthieno[3,2-b]pyridin-7-yl)urea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0401963
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3-nitrophenyl)furan-2-yl]methanone
Show/Hide
|
C27H29ClN4O5
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0401981
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2,4-difluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H28ClF2N3O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0517638
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(4-methoxyphenyl)furan-2-yl]methanone
Show/Hide
|
C28H32ClN3O4
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0517637
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(4-nitrophenyl)furan-2-yl]methanone
Show/Hide
|
C27H29ClN4O5
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0445864
|
[5-(2-chlorophenyl)furan-2-yl]-[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]methanone
Show/Hide
|
C27H29Cl2N3O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0519265
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3,4-dimethoxyphenyl)furan-2-yl]methanone
Show/Hide
|
C29H34ClN3O5
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0406688
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C22H26N4O2S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0540243
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[(4-thiophen-3-ylphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C51H65N9O10S3
|
1
|
| 1 |
IC50 = 36.31 nM
|
|
|
|
CP0479101
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3,4,5-trifluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H27ClF3N3O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0382602
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3,4-dichlorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H28Cl3N3O3
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0397037
|
1-[2-[4-[(3-bromophenyl)methyl]-4-hydroxypiperidin-1-yl]ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C22H25BrN4O2S
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0450718
|
3-[5-[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazine-1-carbonyl]furan-2-yl]benzonitrile
Show/Hide
|
C28H29ClN4O3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0481788
|
2-[5-[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazine-1-carbonyl]furan-2-yl]benzonitrile
Show/Hide
|
C28H29ClN4O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0484693
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-(5-phenylfuran-2-yl)methanone
Show/Hide
|
C27H30ClN3O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0442782
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-(4-methoxyphenyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H36BrN3O3S
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0489387
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-nitro-1-benzothiophene-2-carboxamide
Show/Hide
|
C26H29BrN4O4S
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0442777
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-chloro-1-benzothiophene-2-carboxamide
Show/Hide
|
C26H29BrClN3O2S
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0450339
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-fluoro-1-benzothiophene-2-carboxamide
Show/Hide
|
C26H29BrFN3O2S
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0498646
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(5-ethylthieno[3,2-b]pyridin-7-yl)urea
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0491641
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(4-phenylphenyl)furan-2-yl]methanone
Show/Hide
|
C33H34ClN3O3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0401979
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(3,5-difluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H28ClF2N3O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0380667
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C26H30BrN3O2S
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0477131
|
[5-(4-chlorophenyl)furan-2-yl]-[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]methanone
Show/Hide
|
C27H29Cl2N3O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0401980
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(4-fluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H29ClFN3O3
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0465053
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-methyl-1-benzothiophene-2-carboxamide
Show/Hide
|
C27H32BrN3O2S
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0576383
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-(4-fluorophenyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H33BrFN3O2S
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0550830
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(2-methylthieno[3,2-b]pyridin-7-yl)urea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0419761
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-cyano-1-benzothiophene-2-carboxamide
Show/Hide
|
C27H29BrN4O2S
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0569686
|
5-bromo-N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C26H29Br2N3O2S
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0481814
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-(3-methoxyphenyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H36BrN3O3S
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0442781
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-phenyl-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H34BrN3O2S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0479073
|
[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazin-1-yl]-[5-(2-fluorophenyl)furan-2-yl]methanone
Show/Hide
|
C27H29ClFN3O3
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0442779
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-methoxy-1-benzothiophene-2-carboxamide
Show/Hide
|
C27H32BrN3O3S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0577250
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-(trifluoromethyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C27H29BrF3N3O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0473394
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[(4-pyridin-3-ylphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C52H66N10O10S2
|
1
|
| 1 |
IC50 = 102.33 nM
|
|
|
|
CP0563610
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]pyridine-2-carboxamide
Show/Hide
|
C23H29BrN4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0450719
|
4-[5-[4-[(3-chloro-4-piperidin-4-yloxyphenyl)methyl]piperazine-1-carbonyl]furan-2-yl]benzonitrile
Show/Hide
|
C28H29ClN4O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0380665
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]thiophene-2-carboxamide
Show/Hide
|
C22H28BrN3O2S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0564371
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[[4-(4-phenylphenyl)phenyl]methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C59H71N9O10S2
|
1
|
| 1 |
IC50 = 134.9 nM
|
|
|
|
CP0504923
|
1-[2-[4-hydroxy-4-[(3-methylphenyl)methyl]piperidin-1-yl]ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0450340
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-(4-methylphenyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H36BrN3O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0465055
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-(4-chlorophenyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H33BrClN3O2S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0511284
|
(2S)-2-[[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-19-[[(2S)-2-aminopropanoyl]amino]-16-benzyl-7-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-[(4-pyridin-4-ylphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-methylbutanoic acid
Show/Hide
|
C52H66N10O10S2
|
1
|
| 1 |
IC50 = 154.88 nM
|
|
|
|
CP0098913
|
(S)-3,4-dichloro-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)benzamide
Show/Hide
|
C23H29Cl2N3O2
|
4
|
| 1 |
IC50 = 158.49 nM
|
|
|
| 2 |
IC50 = 170 nM
|
|
|
| 3 |
Ki = 199.53 nM
|
|
|
| 4 |
Ki = 200 nM
|
|
|
|
CP0508035
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(1-methylpyrrolo[2,3-b]pyridin-4-yl)urea
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0442778
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-ethyl-1-benzothiophene-2-carboxamide
Show/Hide
|
C28H34BrN3O2S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0504922
|
1-[2-[4-hydroxy-4-[(4-methylphenyl)methyl]piperidin-1-yl]ethyl]-3-thieno[3,2-b]pyridin-7-ylurea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0448378
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)urea
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0442780
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-5-phenyl-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H34BrN3O2S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0380666
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-1,2-oxazole-5-carboxamide
Show/Hide
|
C21H27BrN4O3
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0498647
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-furo[3,2-b]pyridin-7-ylurea
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0138744
|
N-butyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C15H17N3
|
2
|
| 1 |
IC50 = 501.19 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0567701
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-6-(2-methoxyphenyl)-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H36BrN3O3S
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0426042
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(1-methylpyrrolo[3,2-b]pyridin-7-yl)urea
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0419760
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]pyrazine-2-carboxamide
Show/Hide
|
C22H28BrN5O2
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0436673
|
Benzo[b]thiophene-2-carboxylic acid ((S)-1-{(R)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C31H42N4O3S
|
3
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
Ki = 110 nM
|
|
|
| 3 |
Ki = 125.89 nM
|
|
|
|
CP0440500
|
2-((3,4-dichlorophenyl)(methyl)amino)-1-(2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C19H27Cl2N3O
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
Ki = 398.11 nM
|
|
|
|
CP0489386
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]furan-2-carboxamide
Show/Hide
|
C22H28BrN3O3
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0536637
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-thieno[2,3-b]pyridin-4-ylurea
Show/Hide
|
C22H26N4O2S
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
|
CP0525549
|
N-[1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]piperidin-4-yl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H27BrN4O2S
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0433190
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(3-methylthieno[3,2-b]pyridin-7-yl)urea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 1230 nM
|
|
|
|
CP0571612
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(3-methylimidazo[4,5-b]pyridin-7-yl)urea
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 2140 nM
|
|
|
|
CP0448377
|
1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(3-bromothieno[3,2-b]pyridin-7-yl)urea
Show/Hide
|
C22H25BrN4O2S
|
1
|
| 1 |
IC50 = 3220 nM
|
|
|
|
CP0091720
|
6,7-dichloro-4-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C26H29Cl2N3O3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0269878
|
6,7-dimethyl-4-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C28H35N3O3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0205663
|
6,7-dichloro-1-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]quinoxalin-2-one
Show/Hide
|
C26H28Cl2N4O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0185920
|
6,7-dimethyl-1-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]quinoxalin-2-one
Show/Hide
|
C28H34N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0215592
|
5-chloro-3-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-1,3-benzothiazol-2-one
Show/Hide
|
C25H28ClN3O2S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0156500
|
6,7-dichloro-4-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C26H29Cl2N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0156502
|
2-(3,4-dichloro-N-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]anilino)acetonitrile
Show/Hide
|
C26H30Cl2N4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0205662
|
6,7-dichloro-1-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]quinoxalin-2-one
Show/Hide
|
C26H28Cl2N4O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0504305
|
N-[(2S)-1-[[(3S)-1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]pyrrolidin-3-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H39BrN4O3S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0398931
|
N-pentyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0251896
|
5-chloro-3-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-1,3-benzoxazol-2-one
Show/Hide
|
C25H28ClN3O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0309084
|
6,7-dimethyl-1-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]quinoxalin-2-one
Show/Hide
|
C28H34N4O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0479472
|
N-[(3S)-1-[[3-bromo-4-[(3R)-pyrrolidin-3-yl]oxyphenyl]methyl]pyrrolidin-3-yl]-3,4-dichlorobenzamide
Show/Hide
|
C22H24BrCl2N3O2
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0156499
|
5-chloro-3-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]-1,3-benzothiazol-2-one
Show/Hide
|
C25H28ClN3O3S
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0156501
|
2-(3,4-dichloro-N-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]anilino)acetonitrile
Show/Hide
|
C26H30Cl2N4O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0455294
|
N-(cyclopropylmethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C15H15N3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0525989
|
N-hexyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C17H21N3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0911102
|
2-(5-bromobenzo[b]thiophen-3-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H29BrN2OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0159839
|
2-[3,4-dichloro-N-(2-methoxyethyl)anilino]-1-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethanone
Show/Hide
|
C27H35Cl2N3O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0474218
|
N-(cyclohexylmethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C18H21N3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0491861
|
N-(2-methylbutyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0439174
|
(S)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28BrCl2N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0431540
|
N-[(2S)-1-[[(3S)-1-(3-bromo-4-piperidin-4-yloxyphenyl)sulfonylpyrrolidin-3-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H37BrN4O5S2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0372287
|
N-benzyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C18H15N3
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0386193
|
N-(2-ethoxyethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0458877
|
N-(3-methylbutyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0479471
|
(S)-N-(1-(3-chloro-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28Cl3N3O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0902675
|
2-(5-methylbenzo[b]thiophen-3-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C27H32N2OS
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0043103
|
(+/-)-2-((3,4-dichlorophenyl)(methyl)amino)-1-(3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C25H31Cl2N3O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0479468
|
N-[(2S)-1-[[(3S)-1-[2-[3-bromo-4-[(3R)-pyrrolidin-3-yl]oxyphenyl]ethyl]pyrrolidin-3-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H39BrN4O3S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0553180
|
N-(2-methoxyethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0504222
|
N-propyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C14H15N3
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0519726
|
N-(thiophen-2-ylmethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H13N3S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0924776
|
cis-2-(5-chlorobenzo[b]thiophen-3-yl)-1-(3-cyclohexyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H35ClN2OS
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0524189
|
N-butyl-8-methoxy-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C16H19N3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0877383
|
2-((3,4-dichlorophenyl)(ethyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H33Cl2N3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0893503
|
trans-2-(5-chlorobenzo[b]thiophen-3-yl)-1-(5-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H29ClN2OS
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0945137
|
cis-2-(5-chlorobenzo[b]thiophen-3-yl)-1-(3-propoxy-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C23H31ClN2O2S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0439812
|
(S)-N-(1-(3-methoxy-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C25H31Cl2N3O3
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0256290
|
5-chloro-3-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
|
C25H28ClN3O4
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0525880
|
(+/-)-N-(1-(3-bromo-4-(1-methylpyrrolidin-3-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H26BrCl2N3O2
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0479470
|
(S)-N-(1-(4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H29Cl2N3O2
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0555098
|
N-[(3S)-1-[[3-bromo-4-[(3S)-pyrrolidin-3-yl]oxyphenyl]methyl]pyrrolidin-3-yl]-3,4-dichlorobenzamide
Show/Hide
|
C22H24BrCl2N3O2
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0915954
|
(+/-)-N-(1-(3-chloro-4-(1-methylpyrrolidin-3-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H26Cl3N3O2
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0491860
|
N-butyl-5-methylpyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0532009
|
N-butyl-6-chloro-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C15H16ClN3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0876372
|
2-((cyclopropylmethyl)(3,4-dichlorophenyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C28H35Cl2N3O
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0444651
|
(S)-N-(1-(3-bromo-4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H28BrCl2N3O2
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0439173
|
(S)-N-(1-(3-fluoro-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28Cl2FN3O2
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0386194
|
N-butyl-5-propan-2-ylpyrido[4,3-b]indol-1-amine
Show/Hide
|
C18H23N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0474228
|
N-butyl-6-methyl-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0942289
|
2-(3,4-dichlorophenylamino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C24H29Cl2N3O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0441491
|
(S)-N-(1-(3-nitro-4-(piperidin-4-yloxy)phenethyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28Cl2N4O4
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0555097
|
(+/-)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfonyl)azepan-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28BrCl2N3O4S
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0156503
|
2-(3,4-dichloro-N-methylanilino)-1-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]ethanone
Show/Hide
|
C25H31Cl2N3O2
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0386195
|
N-butyl-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C15H17N3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0497874
|
N-(oxolan-2-ylmethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0893505
|
2-(naphthalen-1-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C28H32N2O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0893506
|
2-((3-chlorophenyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C25H32ClN3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0893507
|
N-(3,4-dichlorophenyl)-N-(2-oxo-2-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethyl)methanesulfonamide
Show/Hide
|
C25H31Cl2N3O3S
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0441493
|
(+/-)-N-(1-(4-(1-methylpyrrolidin-3-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0524188
|
N-(2-phenylethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C19H17N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0525993
|
N-(cyclopropylmethyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C15H15N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0876371
|
2-(methyl(3-(trifluoromethyl)phenyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H32F3N3O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0880941
|
(+/-)-N-(1-(3-methyl-4-(1-methylpyrrolidin-3-yloxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H29Cl2N3O2
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0441488
|
(S)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfonyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C22H24BrCl2N3O4S
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0853189
|
3,4-Dichloro-N-((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-benzamide
Show/Hide
|
C29H40Cl2N4O3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0185921
|
2-[3,4-dichloro-N-(2-methoxyethyl)anilino]-1-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]ethanone
Show/Hide
|
C27H35Cl2N3O3
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0419048
|
N-[1-(3-bromo-4-piperidin-4-yloxyphenyl)sulfonylpiperidin-4-yl]-3,4-dichlorobenzamide
Show/Hide
|
C23H26BrCl2N3O4S
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0916657
|
Benzofuran-2-carboxylic acid ((S)-1-{(R)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C31H42N4O4
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0921800
|
2-(methyl(naphthalen-2-yl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C29H35N3O
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0899555
|
4-Bromo-N-((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-benzamide
Show/Hide
|
C29H41BrN4O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0893504
|
cis-2-(5-chlorobenzo[b]thiophen-3-yl)-1-(4-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H29ClN2OS
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0902674
|
cis-2-(5-chlorobenzo[b]thiophen-3-yl)-1-(-3-methyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C21H27ClN2OS
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0922383
|
2-((3,4-dimethylphenyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C27H37N3O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0444650
|
(S)-N-(1-(4-(1-benzylpiperidin-4-yloxy)-3-bromobenzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C30H32BrCl2N3O2
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0878037
|
((S)-1-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-carbamic acid phenyl ester
Show/Hide
|
C29H42N4O4
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0876370
|
2-(benzo[b]thiophen-3-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H30N2OS
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0461407
|
(S)-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)-4-bromobenzamide
Show/Hide
|
C23H30BrN3O2
|
2
|
| 1 |
Ki = 316.23 nM
|
|
|
| 2 |
Ki = 320 nM
|
|
|
|
CP0527966
|
N-(2-methoxyethyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0525881
|
(R)-N-(1-(4-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)-4-bromobenzamide
Show/Hide
|
C23H30BrN3O2
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0479469
|
(R)-N-(1-(3-bromo-4-(piperidin-4-yloxy)phenylsulfonyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C22H24BrCl2N3O4S
|
1
|
| 1 |
Ki = 380 nM
|
|
|
|
CP0899554
|
(S)-2-(2-Benzo[1,3]dioxol-5-yl-acetylamino)-4-methyl-pentanoic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C31H44N4O5
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0916292
|
3,4-Dichloro-N-((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-2-phenyl-ethyl)-benzamide
Show/Hide
|
C32H38Cl2N4O3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0925796
|
Thiophene-2-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C27H40N4O3S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0922382
|
2-(methyl(m-tolyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H35N3O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0444652
|
3,4-dichloro-N-[1-[[4-[3-(dimethylamino)propoxy]phenyl]methyl]piperidin-4-yl]benzamide
Show/Hide
|
C24H31Cl2N3O2
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0916291
|
1H-Indole-2-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C31H43N5O3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0917247
|
N-((S)-1-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-benzamide
Show/Hide
|
C29H42N4O3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0925794
|
Benzo[1,3]dioxole-5-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C30H42N4O5
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0921798
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C20H25ClN2OS
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0922046
|
2-((4-chlorophenyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C25H32ClN3O
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0853778
|
4-Bromo-N-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-3-methyl-benzamide
Show/Hide
|
C24H32BrN3O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0875087
|
Quinoline-2-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C32H43N5O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0916909
|
4-Chloro-N-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-3-methyl-benzamide
Show/Hide
|
C24H32ClN3O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0917246
|
Furan-2-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C27H40N4O4
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0942240
|
2-(5-bromo-1H-indol-3-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H30BrN3O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0875088
|
3,4-Dichloro-N-((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-2-methyl-propyl)-benzamide
Show/Hide
|
C28H38Cl2N4O3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0397107
|
N,N-dibutyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C19H25N3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0412305
|
N-(cyclohexylmethyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C18H21N3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0490195
|
N-pentan-2-yl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0924778
|
2-((3-methoxyphenyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0942241
|
2-((2-chlorophenyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C25H32ClN3O
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0955432
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(3-(pyrrolidin-1-ylmethyl)morpholino)ethanone
Show/Hide
|
C19H23ClN2O2S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0916659
|
(S)-4-Methyl-2-(3-phenyl-ureido)-pentanoic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C29H43N5O3
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0942242
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-((2S,3S)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H29ClN2OS
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0525879
|
(S)-N-(1-(3-bromo-4-(2-(pyrrolidin-1-yl)ethoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28BrCl2N3O2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0893502
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-(morpholinomethyl)piperidin-1-yl)ethanone
Show/Hide
|
C20H25ClN2O2S
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0495917
|
(S)-N-(1-(3-bromo-4-(2-(piperazin-1-yl)ethoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H29BrCl2N4O2
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0458876
|
N-ethyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C13H13N3
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0235117
|
2-((3,4-dichlorophenyl)(methyl)amino)-1-((2S,3S)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C25H31Cl2N3O
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0910411
|
N-(3,4-dichlorophenyl)-N-(2-oxo-2-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethyl)acetamide
Show/Hide
|
C26H31Cl2N3O2
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0854862
|
3,5-Dichloro-N-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-benzamide
Show/Hide
|
C23H29Cl2N3O2
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0916658
|
N-((S)-1-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-isonicotinamide
Show/Hide
|
C28H41N5O3
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0945017
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-(pyrrolidin-1-ylmethyl)azepan-1-yl)ethanone
Show/Hide
|
C21H27ClN2OS
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0880331
|
Benzo[1,3]dioxole-5-carboxylic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C24H31N3O4
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0911860
|
N-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-benzamide
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0915682
|
Benzofuran-2-carboxylic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0927048
|
(S)-2-Acetylamino-4-methyl-pentanoic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C24H40N4O3
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0519725
|
N-cyclopropyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C14H13N3
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0945139
|
2-(3,4-dichlorophenyl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C24H28Cl2N2O
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0919315
|
Benzofuran-2-carboxylic acid ((R)-1-{(R)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C31H42N4O4
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0922381
|
2-(methyl(phenyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C25H33N3O
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0945138
|
3-(5-methylbenzo[b]thiophen-3-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)propan-1-one
Show/Hide
|
C28H34N2OS
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0525878
|
(S)-N-(1-(3-bromo-4-(2-morpholinoethoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C24H28BrCl2N3O3
|
1
|
| 1 |
Ki = 3500 nM
|
|
|
|
CP0525992
|
5-benzyl-N-butylpyrido[4,3-b]indol-1-amine
Show/Hide
|
C22H23N3
|
1
|
| 1 |
Ki = 3981.07 nM
|
|
|
|
CP0913728
|
2-((3,4-dichlorobenzyl)(methyl)amino)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C26H33Cl2N3O
|
1
|
| 1 |
Ki = 3981.07 nM
|
|
|
|
CP0924777
|
2-(naphthalen-2-yl)-1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C28H32N2O
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
|
CP0942239
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-(piperidin-1-ylmethyl)piperidin-1-yl)ethanone
Show/Hide
|
C21H27ClN2OS
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
|
CP0441058
|
(4-(4-(3-(dimethylamino)propoxy)benzyl)piperazin-1-yl)(3,4-dichlorophenyl)methanone
Show/Hide
|
C23H29Cl2N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0479473
|
3,4-dichloro-N-[3-[[4-[3-(dimethylamino)propoxy]phenyl]methyl-methylamino]propyl]benzamide
Show/Hide
|
C23H31Cl2N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0514706
|
(S)-N-(1-(2-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H29Cl2N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0441057
|
(S)-N-(1-(3-(3-(dimethylamino)propoxy)benzyl)pyrrolidin-3-yl)-3,4-dichlorobenzamide
Show/Hide
|
C23H29Cl2N3O2
|
1
|
| 1 |
Ki > 3000 nM
|
|
|
|
CP0388302
|
N-(2-methoxyethyl)-N-methyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0489885
|
N-[2-(5H-pyrido[4,3-b]indol-1-ylamino)ethyl]acetamide
Show/Hide
|
C15H16N4O
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0519727
|
N-(2-morpholin-4-ylethyl)-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C17H20N4O
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0525990
|
N-phenyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C17H13N3
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0525991
|
3-(5H-pyrido[4,3-b]indol-1-ylamino)propanamide
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0526740
|
N-cyclohexyl-5H-pyrido[4,3-b]indol-1-amine
Show/Hide
|
C17H19N3
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0553181
|
N',N'-dimethyl-N-(5H-pyrido[4,3-b]indol-1-yl)ethane-1,2-diamine
Show/Hide
|
C15H18N4
|
1
|
| 1 |
Ki > 7943.28 nM
|
|
|
|
CP0858842
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)ethanone
Show/Hide
|
C19H23ClN2OS
|
1
|
| 1 |
Ki < 7943.28 nM
|
|
|
|
CP0913727
|
naphthalen-1-yl((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)methanone
Show/Hide
|
C27H30N2O
|
1
|
| 1 |
Ki < 7943.28 nM
|
|
|
|
CP0921799
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-((diethylamino)methyl)piperidin-1-yl)ethanone
Show/Hide
|
C20H27ClN2OS
|
1
|
| 1 |
Ki < 7943.28 nM
|
|
|
|
CP0922043
|
1-((2R,3R)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)-2-(thiophen-3-yl)ethanone
Show/Hide
|
C22H28N2OS
|
1
|
| 1 |
Ki < 7943.28 nM
|
|
|
|
CP0922380
|
2-(5-chlorobenzo[b]thiophen-3-yl)-1-(2-((4-methylpiperazin-1-yl)methyl)piperidin-1-yl)ethanone
Show/Hide
|
C21H28ClN3OS
|
1
|
| 1 |
Ki < 7943.28 nM
|
|
|
|
CP0847646
|
N-((S)-4-Amino-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-butyl)-3,4-dichloro-benzamide
Show/Hide
|
C28H39Cl2N5O3
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0853779
|
Biphenyl-4-carboxylic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C29H35N3O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0853780
|
N-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-isonicotinamide
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0880330
|
N-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-4-trifluoromethyl-benzamide
Show/Hide
|
C24H30F3N3O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0880332
|
Naphthalene-2-carboxylic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C27H33N3O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0911861
|
Furan-2-carboxylic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C21H29N3O3
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0915681
|
N-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-3,4-dimethyl-benzamide
Show/Hide
|
C25H35N3O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0915684
|
(S)-4-(3,4-Dichloro-benzoylamino)-4-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-butyric acid
Show/Hide
|
C28H36Cl2N4O5
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0916405
|
Benzo[b]thiophene-2-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C31H42N4O3S
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0916495
|
N-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-3,4-dimethoxy-benzamide
Show/Hide
|
C25H35N3O4
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0916660
|
3,4-Dichloro-N-({(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-methyl)-benzamide
Show/Hide
|
C25H32Cl2N4O3
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0916910
|
Thiophene-2-carboxylic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C21H29N3O2S
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0916911
|
N-{(S)-1-[4-(3-Dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-acetamide
Show/Hide
|
C18H29N3O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0917245
|
Benzofuran-2-carboxylic acid ((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-amide
Show/Hide
|
C31H42N4O4
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
|
CP0917607
|
4-Cyano-N-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-benzamide
Show/Hide
|
C24H30N4O2
|
1
|
| 1 |
Ki < 10000 nM
|
|
|
