General Information of the Compound
Compound ID
CP0893504
Compound Name
cis-2-(5-chlorobenzo[b]thiophen-3-yl)-1-(4-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone
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Structure
Formula
C26H29ClN2OS
Molecular Weight
453.051
Canonical SMILES
O=C(Cc1csc2ccc(Cl)cc12)N1CC[C@H](c2ccccc2)C[C@@H]1CN1CCCC1
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InChI
InChI=1S/C26H29ClN2OS/c27-22-8-9-25-24(16-22)21(18-31-25)15-26(30)29-13-10-20(19-6-2-1-3-7-19)14-23(29)17-28-11-4-5-12-28/h1-3,6-9,16,18,20,23H,4-5,10-15,17H2/t20-,23+/m0/s1
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InChIKey
OZRGMSXVRJQDCT-NZQKXSOJSA-N
Physicochemical Property
logP
5.9678
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
23.55
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44448474
ChEMBL ID
CHEMBL256140
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 199.53 nM
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   LI
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