General Information of the Compound
Compound ID
CP0899554
Compound Name
(S)-2-(2-Benzo[1,3]dioxol-5-yl-acetylamino)-4-methyl-pentanoic acid {(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-yl}-amide
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Structure
Formula
C31H44N4O5
Molecular Weight
552.716
Canonical SMILES
CC(C)C[C@H](NC(=O)Cc1ccc2c(c1)OCO2)C(=O)N[C@H]1CCN(Cc2ccc(OCCCN(C)C)cc2)C1
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InChI
InChI=1S/C31H44N4O5/c1-22(2)16-27(33-30(36)18-24-8-11-28-29(17-24)40-21-39-28)31(37)32-25-12-14-35(20-25)19-23-6-9-26(10-7-23)38-15-5-13-34(3)4/h6-11,17,22,25,27H,5,12-16,18-21H2,1-4H3,(H,32,37)(H,33,36)/t25-,27-/m0/s1
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InChIKey
FIJHMGZJAOFINH-BDYUSTAISA-N
Physicochemical Property
logP
3.2099
Rotatable Bonds
14
Heavy Atom Count
40
Polar Areas
92.37
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44399062
ChEMBL ID
CHEMBL193133
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 398.11 nM
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