General Information of the Compound
Compound ID
CP0916660
Compound Name
3,4-Dichloro-N-({(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-methyl)-benzamide
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Structure
Formula
C25H32Cl2N4O3
Molecular Weight
507.462
Canonical SMILES
CN(C)CCCOc1ccc(CN2CC[C@H](NC(=O)CNC(=O)c3ccc(Cl)c(Cl)c3)C2)cc1
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InChI
InChI=1S/C25H32Cl2N4O3/c1-30(2)11-3-13-34-21-7-4-18(5-8-21)16-31-12-10-20(17-31)29-24(32)15-28-25(33)19-6-9-22(26)23(27)14-19/h4-9,14,20H,3,10-13,15-17H2,1-2H3,(H,28,33)(H,29,32)/t20-/m0/s1
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InChIKey
JWHACHFNEQIFPH-FQEVSTJZSA-N
Physicochemical Property
logP
3.4444
Rotatable Bonds
11
Heavy Atom Count
34
Polar Areas
73.91
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44399055
ChEMBL ID
CHEMBL191554
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki < 10000 nM
   TI
   LI
   LO
   TS