General Information of the Compound
Compound ID
CP0899555
Compound Name
4-Bromo-N-((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-3-methyl-butyl)-benzamide
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Structure
Formula
C29H41BrN4O3
Molecular Weight
573.576
Canonical SMILES
CC(C)C[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N[C@H]1CCN(Cc2ccc(OCCCN(C)C)cc2)C1
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InChI
InChI=1S/C29H41BrN4O3/c1-21(2)18-27(32-28(35)23-8-10-24(30)11-9-23)29(36)31-25-14-16-34(20-25)19-22-6-12-26(13-7-22)37-17-5-15-33(3)4/h6-13,21,25,27H,5,14-20H2,1-4H3,(H,31,36)(H,32,35)/t25-,27-/m0/s1
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InChIKey
XFRNCXGSJUADFM-BDYUSTAISA-N
Physicochemical Property
logP
4.3148
Rotatable Bonds
13
Heavy Atom Count
37
Polar Areas
73.91
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 12052419
ChEMBL ID
CHEMBL191401
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS