General Information of the Compound
Compound ID
CP0916292
Compound Name
3,4-Dichloro-N-((S)-1-{(S)-1-[4-(3-dimethylamino-propoxy)-benzyl]-pyrrolidin-3-ylcarbamoyl}-2-phenyl-ethyl)-benzamide
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Structure
Formula
C32H38Cl2N4O3
Molecular Weight
597.587
Canonical SMILES
CN(C)CCCOc1ccc(CN2CC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)c3ccc(Cl)c(Cl)c3)C2)cc1
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InChI
InChI=1S/C32H38Cl2N4O3/c1-37(2)16-6-18-41-27-12-9-24(10-13-27)21-38-17-15-26(22-38)35-32(40)30(19-23-7-4-3-5-8-23)36-31(39)25-11-14-28(33)29(34)20-25/h3-5,7-14,20,26,30H,6,15-19,21-22H2,1-2H3,(H,35,40)(H,36,39)/t26-,30-/m0/s1
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InChIKey
INQGOZPUMJRPOU-YZNIXAGQSA-N
Physicochemical Property
logP
5.0557
Rotatable Bonds
13
Heavy Atom Count
41
Polar Areas
73.91
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44399084
ChEMBL ID
CHEMBL371361
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 398.11 nM
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