Protein Information

General Information of the Protein

Protein ID	PT01785
Protein Name	Endothelin-1 receptor
Secondarily Protein Name	Endothelin receptor type A
Gene Name	EDNRA
Sequence	MGVLCFLASFWLALVGGAIADNAERYSANLSSHVEDFTPFPGTEFNFLGTTLQPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEQHRTCMLNATTKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNHNTERSSHKDSMN Show/Hide
Organism	Rattus norvegicus, Rat
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Peptide receptor (family A GPCR) > Short peptide receptor (family A GPCR) > Endothelin receptor
Function	Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. Show/Hide
Uniprot ID	P26684
Ensembl ID	ENSG00000151617
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000139 , A-10

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0448553 Compound Info	(R)-4-[2-Cyano-5-(pyridin-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C24H22N2O4	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0454536 Compound Info	(R)-4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C23H21NO4S	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0859991 Compound Info	[2-Cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-o-tolyl-acetic acid Show/Hide	C22H18N2O4	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0943191 Compound Info	Sodium salt [2-cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-o-tolyl-acetate Show/Hide	C22H17N2NaO4	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0374604 Compound Info	(2-Chloro-phenyl)-[2-cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-acetic acid Show/Hide	C21H15ClN2O4	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0460609 Compound Info	2-[5-(1,3-benzoxazol-6-ylmethoxy)-2-cyanophenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C24H18N2O5	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0448272 Compound Info	4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C23H21NO4S	2
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0530637 Compound Info	5-[2-(3-Carboxy-1-o-tolyl-propoxy)-4-(thiophen-3-ylmethoxy)-phenyl]-2H-pyrazole-3-carboxylic acid Show/Hide	C26H24N2O6S	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0541018 Compound Info	(R)-4-[2-Cyano-5-(isothiazol-4-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C22H20N2O4S	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0922562 Compound Info	Sodium salt [5-(benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]-o-tolyl-acetate Show/Hide	C24H18NNaO6	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0372304 Compound Info	2-[2-cyano-5-(pyridin-4-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C22H18N2O4	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0535067 Compound Info	2-[5-(1,3-benzoxazol-6-ylmethoxy)-2-cyanophenoxy]-2-(2-chlorophenyl)acetic acid Show/Hide	C23H15ClN2O5	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0859980 Compound Info	[5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]-o-tolyl-acetic acid Show/Hide	C24H19NO6	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0453320 Compound Info	2-[5-(1,3-benzodioxol-5-ylmethoxy)-2-cyanophenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C24H19NO6	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0156307 Compound Info	CHEBI:2965 Show/Hide	C31H42N6O7	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0377417 Compound Info	2-[5-(1,3-benzodioxol-5-ylmethoxy)-2-cyanophenoxy]-2-(2-chlorophenyl)acetic acid Show/Hide	C23H16ClNO6	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0041337 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0392922 Compound Info	2-[5-(1,3-benzodioxol-5-ylmethoxy)-2-cyanophenoxy]-2-[2-(trifluoromethyl)phenyl]acetic acid Show/Hide	C24H16F3NO6	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0502216 Compound Info	(2-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-acetic acid Show/Hide	C20H14ClNO4S	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0521885 Compound Info	5-Isopropylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C18H21N3O3S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0468139 Compound Info	(R)-4-[2-Cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C24H22N2O4	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0530016 Compound Info	4-[2-Oxazol-2-yl-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C25H23NO5S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0565863 Compound Info	4-[2-(1H-Pyrazol-3-yl)-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C25H24N2O4S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0441008 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C21H17NO4S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0524551 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-(2-fluorophenyl)acetic acid Show/Hide	C20H14FNO4S	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0405716 Compound Info	2-[2-cyano-5-[(2-fluoropyridin-4-yl)methoxy]phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C22H17FN2O4	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0467896 Compound Info	4-[2-Acetyl-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C24H24O5S	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0456930 Compound Info	4-[2-Carbamoyl-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C23H23NO5S	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0392686 Compound Info	5-Pyrrolidin-1-yl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C19H21N3O3S	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0381561 Compound Info	2-[2-cyano-5-(1,3-thiazol-5-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C20H16N2O4S	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0382311 Compound Info	2-[2-cyano-5-(pyridin-3-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C22H18N2O4	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0460795 Compound Info	4-[2-Pyridin-2-yl-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C27H25NO4S	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0493028 Compound Info	2-[5-(1,3-benzodioxol-5-ylmethoxy)-2-cyanophenoxy]-2-phenylacetic acid Show/Hide	C23H17NO6	1
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
CP0437631 Compound Info	(2-Chloro-phenyl)-[2-cyano-5-(pyridazin-4-ylmethoxy)-phenoxy]-acetic acid Show/Hide	C20H14ClN3O4	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0492647 Compound Info	(5-Benzyloxy-2-cyano-phenoxy)-o-tolyl-acetic acid Show/Hide	C23H19NO4	1
1	IC50 = 49 nM Bioactivity Info	TI LI LO TS
CP0475852 Compound Info	(2-Bromo-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-acetic acid (0.5H2O) Show/Hide	C20H14BrNO4S	1
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
CP0428807 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-[2-(trifluoromethyl)phenyl]acetic acid Show/Hide	C21H14F3NO4S	1
1	IC50 = 53 nM Bioactivity Info	TI LI LO TS
CP0460836 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
CP0503374 Compound Info	5-Ethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
CP0466961 Compound Info	2-[2-cyano-5-(furan-3-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C21H17NO5	1
1	IC50 = 68 nM Bioactivity Info	TI LI LO TS
CP0528748 Compound Info	(R)-4-[5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C26H23NO6	1
1	IC50 = 69 nM Bioactivity Info	TI LI LO TS
CP0460551 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-phenylacetic acid Show/Hide	C20H15NO4S	1
1	IC50 = 70 nM Bioactivity Info	TI LI LO TS
CP0403147 Compound Info	2-[5-(1,3-benzoxazol-5-ylmethoxy)-2-cyanophenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C24H18N2O5	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0511481 Compound Info	5-Pentylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C20H25N3O3S	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0530288 Compound Info	(E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-phenyl-acrylic acid Show/Hide	C21H15NO3S	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0502975 Compound Info	(3-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-acetic acid (0.5C4H10O) Show/Hide	C20H14ClNO4S	1
1	IC50 = 98 nM Bioactivity Info	TI LI LO TS
CP0530146 Compound Info	5-Oxo-5-[3-(thiophen-3-ylmethoxy)-phenyl]-4-o-tolyl-pentanoic acid Show/Hide	C23H22O4S	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0565813 Compound Info	(S)-4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C23H21NO4S	1
1	IC50 = 113 nM Bioactivity Info	TI LI LO TS
CP0376479 Compound Info	5-(2-Oxo-pyrrolidin-1-yl)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C19H19N3O4S	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0496528 Compound Info	5-Methylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C16H17N3O3S	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0503029 Compound Info	5-(Isopropyl-methyl-amino)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C19H23N3O3S	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0392703 Compound Info	5-(3-Phenyl-thioureido)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C22H20N4O3S2	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0511365 Compound Info	(E)-3-[2-Cyano-5-(pyridin-3-ylmethoxy)-phenyl]-2-phenyl-acrylic acid Show/Hide	C22H16N2O3	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0407114 Compound Info	(E)-2-Benzo[1,3]dioxol-5-yl-3-[2-cyano-5-(thiophen-3-ylmethoxy)-phenyl]-acrylic acid Show/Hide	C22H15NO5S	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0554896 Compound Info	(E)-2-(2-Chloro-phenyl)-3-[2-cyano-5-(thiophen-3-ylmethoxy)-phenyl]-acrylic acid Show/Hide	C21H14ClNO3S	1
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
CP0463491 Compound Info	2-(3-Carboxy-1-o-tolyl-propoxy)-4-(thiophen-3-ylmethoxy)-benzoic acid Show/Hide	C23H22O6S	1
1	IC50 = 207 nM Bioactivity Info	TI LI LO TS
CP0527456 Compound Info	2-[2-cyano-5-(1,2-thiazol-3-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C20H16N2O4S	1
1	IC50 = 220 nM Bioactivity Info	TI LI LO TS
CP0449137 Compound Info	4-Amino-N-(4,5-dimethyl-isoxazol-3-yl)-benzenesulfonamide Show/Hide	C11H13N3O3S	1
1	IC50 = 260 nM Bioactivity Info	TI LI LO TS
CP0430576 Compound Info	5-(2-Oxo-piperidin-1-yl)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C20H21N3O4S	1
1	IC50 = 270 nM Bioactivity Info	TI LI LO TS
CP0448735 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (4-ethyl-3-methyl-isoxazol-5-yl)-amide Show/Hide	C18H21N3O3S	1
1	IC50 = 290 nM Bioactivity Info	TI LI LO TS
CP0448942 Compound Info	(E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-o-tolyl-acrylic acid Show/Hide	C22H17NO3S	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0511715 Compound Info	2-((E)-3-Hydroxy-2-o-tolyl-propenyl)-4-(thiophen-3-ylmethoxy)-benzonitrile Show/Hide	C22H19NO2S	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0463674 Compound Info	2-[5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen-1-ylamino]-propionic acid ethyl ester Show/Hide	C20H23N3O5S	1
1	IC50 = 400 nM Bioactivity Info	TI LI LO TS
CP0540090 Compound Info	(E)-2-(2-Chloro-phenyl)-3-[2-nitro-5-(thiophen-3-ylmethoxy)-phenyl]-prop-2-en-1-ol Show/Hide	C20H16ClNO4S	1
1	IC50 = 400 nM Bioactivity Info	TI LI LO TS
CP0403840 Compound Info	(E)-3-[2-Nitro-5-(thiophen-3-ylmethoxy)-phenyl]-2-phenyl-acrylic acid Show/Hide	C20H15NO5S	1
1	IC50 = 500 nM Bioactivity Info	TI LI LO TS
CP0449654 Compound Info	(4-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-acetic acid Show/Hide	C20H14ClNO4S	1
1	IC50 = 504 nM Bioactivity Info	TI LI LO TS
CP0431454 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-(2-methoxyphenyl)acetic acid Show/Hide	C21H17NO5S	1
1	IC50 = 529 nM Bioactivity Info	TI LI LO TS
CP0437180 Compound Info	5-Benzylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C22H21N3O3S	1
1	IC50 = 590 nM Bioactivity Info	TI LI LO TS
CP0454830 Compound Info	(E)-2-(2-Fluoro-phenyl)-3-[2-nitro-5-(thiophen-3-ylmethoxy)-phenyl]-acrylic acid Show/Hide	C20H14FNO5S	1
1	IC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0511714 Compound Info	(E)-3-(5-Benzyloxy-2-nitro-phenyl)-2-phenyl-acrylic acid Show/Hide	C22H17NO5	1
1	IC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0534422 Compound Info	(E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-o-tolyl-prop-2-en-1-ol Show/Hide	C21H19BrO2S	1
1	IC50 = 600 nM Bioactivity Info	TI LI LO TS
CP0380160 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-thiophen-3-ylacetic acid Show/Hide	C18H13NO4S2	1
1	IC50 = 630 nM Bioactivity Info	TI LI LO TS
CP0448748 Compound Info	6-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 660 nM Bioactivity Info	TI LI LO TS
CP0511386 Compound Info	(Z)-5-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-4-phenyl-pent-4-enoic acid Show/Hide	C23H19NO3S	1
1	IC50 = 700 nM Bioactivity Info	TI LI LO TS
CP0531612 Compound Info	(E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-phenyl-acrylic acid Show/Hide	C20H15BrO3S	1
1	IC50 = 700 nM Bioactivity Info	TI LI LO TS
CP0040571 Compound Info	4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide Show/Hide	C11H13N3O3S	1
1	IC50 = 780 nM Bioactivity Info	TI LI LO TS
CP0453492 Compound Info	2-((E)-3-Hydroxy-2-phenyl-propenyl)-4-(thiophen-3-ylmethoxy)-benzonitrile Show/Hide	C21H17NO2S	1
1	IC50 = 800 nM Bioactivity Info	TI LI LO TS
CP0395309 Compound Info	6-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 840 nM Bioactivity Info	TI LI LO TS
CP0509142 Compound Info	2-[2-cyano-5-[(2,6-dimethylphenyl)methoxy]phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C25H23NO4	1
1	IC50 = 857 nM Bioactivity Info	TI LI LO TS
CP0373019 Compound Info	N-[8-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-2-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 870 nM Bioactivity Info	TI LI LO TS
CP0530693 Compound Info	4-[3-(Thiophen-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid Show/Hide	C22H22O4S	1
1	IC50 = 871 nM Bioactivity Info	TI LI LO TS
CP0522222 Compound Info	N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 880 nM Bioactivity Info	TI LI LO TS
CP0522223 Compound Info	N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]-2-methylpropanamide Show/Hide	C19H21N3O4S	1
1	IC50 = 880 nM Bioactivity Info	TI LI LO TS
CP0449130 Compound Info	(E)-3-(5-Benzyloxy-2-nitro-phenyl)-2-(2-fluoro-phenyl)-acrylic acid Show/Hide	C22H16FNO5	1
1	IC50 = 900 nM Bioactivity Info	TI LI LO TS
CP0414845 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-fluorobenzenesulfonamide Show/Hide	C11H11FN2O3S	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0461023 Compound Info	5-(2,4-Bis-benzyloxy-phenyl)-1H-pyrazole-3-carboxylic acid Show/Hide	C24H20N2O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0374221 Compound Info	5-(3-Benzyloxy-phenyl)-5-oxo-4-phenyl-pentanoic acid Show/Hide	C24H22O4	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0554889 Compound Info	(E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-(3-methoxy-phenyl)-acrylic acid Show/Hide	C22H17NO4S	1
1	IC50 = 1100 nM Bioactivity Info	TI LI LO TS
CP0430554 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (3-ethyl-4-methyl-isoxazol-5-yl)-amide Show/Hide	C18H21N3O3S	1
1	IC50 = 1170 nM Bioactivity Info	TI LI LO TS
CP0373016 Compound Info	3-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide Show/Hide	C11H13N3O3S	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0404487 Compound Info	N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-2-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0449255 Compound Info	(E)-2-(2-Chloro-phenyl)-3-[2-nitro-5-(thiophen-3-ylmethoxy)-phenyl]-acrylic acid Show/Hide	C20H14ClNO5S	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0460506 Compound Info	(E)-3-[5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenyl]-2-phenyl-acrylic acid Show/Hide	C24H17NO5	1
1	IC50 = 1300 nM Bioactivity Info	TI LI LO TS
CP0463657 Compound Info	7-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0505919 Compound Info	7-Dimethylamino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0507567 Compound Info	(E)-3-[2-Nitro-5-(thiophen-3-ylmethoxy)-phenyl]-2-phenyl-prop-2-en-1-ol Show/Hide	C20H17NO4S	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0481062 Compound Info	2-[2-cyano-5-(2,3-dihydro-1,4-benzodioxin-6-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C25H21NO6	1
1	IC50 = 1500 nM Bioactivity Info	TI LI LO TS
CP0436746 Compound Info	5-Piperidin-1-yl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C20H23N3O3S	1
1	IC50 = 1760 nM Bioactivity Info	TI LI LO TS
CP0520919 Compound Info	4-[5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen-1-ylamino]-butyric acid Show/Hide	C19H21N3O5S	1
1	IC50 = 1960 nM Bioactivity Info	TI LI LO TS
CP0445281 Compound Info	(E)-2-(2-Chloro-6-fluoro-phenyl)-3-[2-nitro-5-(thiophen-3-ylmethoxy)-phenyl]-acrylic acid Show/Hide	C20H13ClFNO5S	1
1	IC50 = 2000 nM Bioactivity Info	TI LI LO TS
CP0532721 Compound Info	4-(3-Benzyloxy-phenoxy)-4-phenyl-butyric acid Show/Hide	C23H22O4	1
1	IC50 = 2000 nM Bioactivity Info	TI LI LO TS
CP0486359 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)-3-(propylamino)benzenesulfonamide Show/Hide	C14H19N3O3S	1
1	IC50 = 2100 nM Bioactivity Info	TI LI LO TS
CP0527755 Compound Info	(E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-phenyl-prop-2-en-1-ol Show/Hide	C20H17BrO2S	1
1	IC50 = 2100 nM Bioactivity Info	TI LI LO TS
CP0373018 Compound Info	6-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 2400 nM Bioactivity Info	TI LI LO TS
CP0437622 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-(furan-2-yl)acetic acid Show/Hide	C18H13NO5S	1
1	IC50 = 2400 nM Bioactivity Info	TI LI LO TS
CP0380216 Compound Info	N-[6-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 2700 nM Bioactivity Info	TI LI LO TS
CP0476037 Compound Info	5-Dimethylaminomethyl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C18H21N3O3S	1
1	IC50 = 2800 nM Bioactivity Info	TI LI LO TS
CP0436961 Compound Info	2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-(furan-3-yl)acetic acid Show/Hide	C18H13NO5S	1
1	IC50 = 2850 nM Bioactivity Info	TI LI LO TS
CP0448644 Compound Info	5-(1-Hydroxy-1-methyl-ethyl)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C18H20N2O4S	1
1	IC50 = 2890 nM Bioactivity Info	TI LI LO TS
CP0542844 Compound Info	(E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-o-tolyl-acrylic acid Show/Hide	C21H17BrO3S	1
1	IC50 = 3000 nM Bioactivity Info	TI LI LO TS
CP0521121 Compound Info	2-[5-(1,3-benzodioxol-4-ylmethoxy)-2-cyanophenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C24H19NO6	1
1	IC50 = 3000 nM Bioactivity Info	TI LI LO TS
CP0486352 Compound Info	5-(5-Phenyl-pentylamino)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C26H29N3O3S	1
1	IC50 = 3050 nM Bioactivity Info	TI LI LO TS
CP0458846 Compound Info	(E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-phenyl-acrylamide Show/Hide	C21H16N2O2S	1
1	IC50 = 3100 nM Bioactivity Info	TI LI LO TS
CP0448542 Compound Info	5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalene-1-carboxylic acid methyl ester Show/Hide	C17H16N2O5S	1
1	IC50 = 3380 nM Bioactivity Info	TI LI LO TS
CP0510002 Compound Info	N-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 3400 nM Bioactivity Info	TI LI LO TS
CP0404627 Compound Info	4-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 3500 nM Bioactivity Info	TI LI LO TS
CP0375922 Compound Info	N-[6-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-2-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 3800 nM Bioactivity Info	TI LI LO TS
CP0009872 Compound Info	4-amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide Show/Hide	C10H11N3O3S	1
1	IC50 = 4000 nM Bioactivity Info	TI LI LO TS
CP0375462 Compound Info	5-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 4000 nM Bioactivity Info	TI LI LO TS
CP0539750 Compound Info	1-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-3-phenylthiourea Show/Hide	C18H18N4O3S2	1
1	IC50 = 4100 nM Bioactivity Info	TI LI LO TS
CP0534469 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (4-methyl-isoxazol-5-yl)-amide Show/Hide	C16H17N3O3S	1
1	IC50 = 4900 nM Bioactivity Info	TI LI LO TS
CP0510974 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-(ethylamino)benzenesulfonamide Show/Hide	C13H17N3O3S	1
1	IC50 = 5000 nM Bioactivity Info	TI LI LO TS
CP0534863 Compound Info	(Z)-5-(3-Benzyloxy-phenyl)-4-phenyl-pent-4-enoic acid Show/Hide	C24H22O3	1
1	IC50 = 5300 nM Bioactivity Info	TI LI LO TS
CP0448537 Compound Info	Biphenyl-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C17H16N2O3S	1
1	IC50 = 5400 nM Bioactivity Info	TI LI LO TS
CP0376471 Compound Info	7-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 5600 nM Bioactivity Info	TI LI LO TS
CP0415327 Compound Info	5-Isopropenyl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C18H18N2O3S	1
1	IC50 = 5700 nM Bioactivity Info	TI LI LO TS
CP0455343 Compound Info	(E)-3-(3-Benzyloxy-phenyl)-2-phenyl-acrylic acid Show/Hide	C22H18O3	1
1	IC50 = 6000 nM Bioactivity Info	TI LI LO TS
CP0427317 Compound Info	5-Methoxy-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C16H16N2O4S	1
1	IC50 = 6500 nM Bioactivity Info	TI LI LO TS
CP0511479 Compound Info	2-Amino-N-[4-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-phenyl]-acetamide Show/Hide	C13H16N4O4S	1
1	IC50 = 6500 nM Bioactivity Info	TI LI LO TS
CP0383380 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)-3-nitrobenzenesulfonamide Show/Hide	C11H11N3O5S	1
1	IC50 = 7800 nM Bioactivity Info	TI LI LO TS
CP0414777 Compound Info	5-(3,3-Diphenyl-propylamino)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C30H29N3O3S	1
1	IC50 = 7800 nM Bioactivity Info	TI LI LO TS
CP0427248 Compound Info	5-Hydroxy-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H14N2O4S	1
1	IC50 = 7800 nM Bioactivity Info	TI LI LO TS
CP0464154 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (3-methyl-isoxazol-5-yl)-amide Show/Hide	C16H17N3O3S	1
1	IC50 = 8900 nM Bioactivity Info	TI LI LO TS
CP0441723 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-hydroxybenzenesulfonamide Show/Hide	C11H12N2O4S	1
1	IC50 = 9200 nM Bioactivity Info	TI LI LO TS
CP0448219 Compound Info	4-Benzylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide Show/Hide	C18H19N3O3S	1
1	IC50 = 9800 nM Bioactivity Info	TI LI LO TS
CP0511480 Compound Info	8-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 9800 nM Bioactivity Info	TI LI LO TS
CP0463669 Compound Info	7-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0430494 Compound Info	2-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]anilino]acetic acid Show/Hide	C13H15N3O5S	1
1	IC50 = 12000 nM Bioactivity Info	TI LI LO TS
CP0374773 Compound Info	N-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]acetamide Show/Hide	C13H15N3O4S	1
1	IC50 = 13000 nM Bioactivity Info	TI LI LO TS
CP0380128 Compound Info	5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalene-1-carboxylic acid Show/Hide	C16H14N2O5S	1
1	IC50 = 13000 nM Bioactivity Info	TI LI LO TS
CP0398048 Compound Info	5-Dibutylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C23H31N3O3S	1
1	IC50 = 15900 nM Bioactivity Info	TI LI LO TS
CP0529915 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (3-methyl-4-phenyl-isoxazol-5-yl)-amide Show/Hide	C22H21N3O3S	1
1	IC50 = 15900 nM Bioactivity Info	TI LI LO TS
CP0380217 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (3-methyl-4-nitro-isoxazol-5-yl)-amide Show/Hide	C16H16N4O5S	1
1	IC50 = 17300 nM Bioactivity Info	TI LI LO TS
CP0429826 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)naphthalene-1-sulfonamide Show/Hide	C15H14N2O3S	1
1	IC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0443774 Compound Info	(E)-3-(3-Benzyloxy-phenyl)-2-phenyl-prop-2-en-1-ol Show/Hide	C22H20O2	1
1	IC50 = 20000 nM Bioactivity Info	TI LI LO TS
CP0464961 Compound Info	5-Chloro-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H13ClN2O3S	1
1	IC50 = 24000 nM Bioactivity Info	TI LI LO TS
CP0498563 Compound Info	5-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C15H15N3O3S	1
1	IC50 = 24000 nM Bioactivity Info	TI LI LO TS
CP0486361 Compound Info	N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-(propylamino)benzenesulfonamide Show/Hide	C14H19N3O3S	1
1	IC50 = 27000 nM Bioactivity Info	TI LI LO TS
CP0404628 Compound Info	N-[7-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 27500 nM Bioactivity Info	TI LI LO TS
CP0391264 Compound Info	4-Amino-N-(3-methyl-isoxazol-5-yl)-benzenesulfonamide Show/Hide	C10H11N3O3S	1
1	IC50 = 28000 nM Bioactivity Info	TI LI LO TS
CP0506640 Compound Info	4-Hydroxy-N-thiazol-2-yl-benzenesulfonamide Show/Hide	C9H8N2O3S2	1
1	IC50 = 30000 nM Bioactivity Info	TI LI LO TS
CP0380253 Compound Info	5-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-methyl-isoxazole-4-carboxylic acid ethyl ester Show/Hide	C19H21N3O5S	1
1	IC50 = 31000 nM Bioactivity Info	TI LI LO TS
CP0496618 Compound Info	8-Dimethylamino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C17H19N3O3S	1
1	IC50 = 31500 nM Bioactivity Info	TI LI LO TS
CP0404626 Compound Info	4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzamide Show/Hide	C12H13N3O2	1
1	IC50 > 32000 nM Bioactivity Info	TI LI LO TS
CP0415481 Compound Info	4-Amino-N-(5-phenyl-isoxazol-3-yl)-benzenesulfonamide Show/Hide	C15H13N3O3S	1
1	IC50 > 32000 nM Bioactivity Info	TI LI LO TS
CP0423103 Compound Info	4-Amino-N-(5-tert-butyl-isoxazol-3-yl)-benzenesulfonamide Show/Hide	C13H17N3O3S	1
1	IC50 > 32000 nM Bioactivity Info	TI LI LO TS
CP0496534 Compound Info	4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-N-methyl-benzenesulfonamide Show/Hide	C12H15N3O3S	1
1	IC50 > 32000 nM Bioactivity Info	TI LI LO TS
CP0501206 Compound Info	4-Amino-N-(4,5,6,7-tetrahydro-benzo[d]isoxazol-3-yl)-benzenesulfonamide Show/Hide	C13H15N3O3S	1
1	IC50 > 32000 nM Bioactivity Info	TI LI LO TS
CP0520369 Compound Info	2-[(4-aminophenyl)sulfonyl-(3,4-dimethyl-1,2-oxazol-5-yl)amino]acetic acid Show/Hide	C13H15N3O5S	1
1	IC50 > 32000 nM Bioactivity Info	TI LI LO TS
CP0424329 Compound Info	1-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-3-phenylurea Show/Hide	C18H18N4O4S	1
1	IC50 = 38000 nM Bioactivity Info	TI LI LO TS
CP0454713 Compound Info	5-(Benzhydrylidene-amino)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide Show/Hide	C28H23N3O3S	1
1	IC50 = 39000 nM Bioactivity Info	TI LI LO TS
CP0520188 Compound Info	N-[7-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-2-yl]acetamide Show/Hide	C17H17N3O4S	1
1	IC50 = 42000 nM Bioactivity Info	TI LI LO TS
CP0463586 Compound Info	N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]-3,3-diphenylpropanamide Show/Hide	C30H27N3O4S	1
1	IC50 = 46000 nM Bioactivity Info	TI LI LO TS
CP0436891 Compound Info	5-Dimethylamino-naphthalene-1-sulfonic acid (4-benzyl-3-methyl-isoxazol-5-yl)-amide Show/Hide	C23H23N3O3S	1
1	IC50 = 50000 nM Bioactivity Info	TI LI LO TS
CP0423200 Compound Info	4-Hydroxy-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide Show/Hide	C10H10N2O4S	1
1	IC50 = 53000 nM Bioactivity Info	TI LI LO TS
CP0052017 Compound Info	4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamide Show/Hide	C8H8N4O2S2	1
1	IC50 = 57000 nM Bioactivity Info	TI LI LO TS
CP0067692 Compound Info	2-(Sulfanilylamino)thiazole Show/Hide	C9H9N3O2S2	1
1	IC50 = 69000 nM Bioactivity Info	TI LI LO TS
CP0493020 Compound Info	2-[2-cyano-5-(pyridin-2-ylmethoxy)phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C22H18N2O4	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0507643 Compound Info	2-[2-cyano-5-[(3,4,5-trimethoxyphenyl)methoxy]phenoxy]-2-(2-methylphenyl)acetic acid Show/Hide	C26H25NO7	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000238 , A7r5

Cell Line Info

Cell Line ID: CL000304 , MMQ

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0037579 Compound Info	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid Show/Hide	C29H38N2O6	3
1	IC50 = 0.08 nM
2	Ki = 0.034 nM
3	Ki = 0.047 nM
CP0156307 Compound Info	CHEBI:2965 Show/Hide	C31H42N6O7	1
1	IC50 = 28 nM
CP0231801 Compound Info	(4aS,6aR,6aR,6bR,8aR,12aR,14bS)-6a-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-2,2,6b,9,9,12a-hexamethyl-10-oxo-3,4,5,6,6a,7,8,8a,11,12,13,14b-dodecahydro-1H-picene-4a-carboxylic acid Show/Hide	C39H52O7	1
1	IC50 = 66 nM

Similar Protein(s) and Bioactivity Statistics

90% Identity

Protein ID	Protein Name	Protein Organism
PT01372	Endothelin-1 receptor	Homo sapiens, Human	Protein Info
PT06168	Endothelin-1 receptor	Mus musculus, Mouse	Protein Info

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han