Brief Information of the Compound and Protein
Compound Name
2-((E)-3-Hydroxy-2-o-tolyl-propenyl)-4-(thiophen-3-ylmethoxy)-benzonitrile
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PubChem ID
CID: 10522605
SID: 15548506
Canonical SMILES
Cc1ccccc1\C(CO)=C/c1cc(OCc2ccsc2)ccc1C#N
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Compound Formula C22H19NO2S
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000139 A-10 Rattus norvegicus (Rat)  1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS