General Information of the Cell Line
Cell Line ID
CL000139
Cell Line Name
A-10
Synonyms
A10
Category
Spontaneously immortalized cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0130
Tissue Information
Aorta
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01372, Endothelin-1 receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0041337
 Compound Info 
5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide
   Show/Hide
C17H19N3O3S
  3
1
IC50 = 150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 570 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
Ki = 55 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0040571
 Compound Info 
4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide
   Show/Hide
C11H13N3O3S
  1
1
IC50 = 780 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0522222
 Compound Info 
N-[5-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]naphthalen-1-yl]acetamide
   Show/Hide
C17H17N3O4S
  1
1
IC50 = 880 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0476037
 Compound Info 
5-Dimethylaminomethyl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
   Show/Hide
C18H21N3O3S
  1
1
IC50 = 2800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0375462
 Compound Info 
5-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
   Show/Hide
C15H15N3O3S
  1
1
IC50 = 4000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0415327
 Compound Info 
5-Isopropenyl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
   Show/Hide
C18H18N2O3S
  1
1
IC50 = 5700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0427317
 Compound Info 
5-Methoxy-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
   Show/Hide
C16H16N2O4S
  1
1
IC50 = 6500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441723
 Compound Info 
N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-hydroxybenzenesulfonamide
   Show/Hide
C11H12N2O4S
  1
1
IC50 = 9200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0448219
 Compound Info 
4-Benzylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide
   Show/Hide
C18H19N3O3S
  1
1
IC50 = 9800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380128
 Compound Info 
5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalene-1-carboxylic acid
   Show/Hide
C16H14N2O5S
  1
1
IC50 = 13000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0429826
 Compound Info 
N-(3,4-dimethyl-1,2-oxazol-5-yl)naphthalene-1-sulfonamide
   Show/Hide
C15H14N2O3S
  1
1
IC50 = 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486361
 Compound Info 
N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-(propylamino)benzenesulfonamide
   Show/Hide
C14H19N3O3S
  1
1
IC50 = 27000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391264
 Compound Info 
4-Amino-N-(3-methyl-isoxazol-5-yl)-benzenesulfonamide
   Show/Hide
C10H11N3O3S
  1
1
IC50 = 28000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0506908
 Compound Info 
4-Cyano-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide
   Show/Hide
C12H11N3O3S
  1
1
IC50 > 32000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0508901
 Compound Info 
4-Dimethylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide
   Show/Hide
C13H17N3O3S
  1
1
IC50 = 84000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01785, Endothelin-1 receptor
 Protein Info 
Protein ID: PT05989, Platelet-derived growth factor receptor beta
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Aorta)
Cell Line Name Organism Disease
BAE1
 Cell Line Info 
Bos taurus (Bovine) -
HAECT-1
 Cell Line Info 
Homo sapiens (Human) -
iHAEC
 Cell Line Info 
Homo sapiens (Human) -
A7r5
 Cell Line Info 
Rattus norvegicus (Rat) -
PAE
 Cell Line Info 
Sus scrofa (Pig) -