General Information of the Cell Line
Cell Line ID
CL000760
Cell Line Name
PAE
Synonyms
pig aortic endothelial
Category
Transformed cell line
Organism
Sus scrofa (Pig)
Cellosaurus ID
CVCL_RX28
Tissue Information
Aorta
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00934, High affinity nerve growth factor receptor
Compound ID Compound Name Compound Formula
CP0186372
5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylsulfanyl]-1,2-thiazole-4-carboxamide
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C16H18N4O2S2
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0186373
5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylsulfanyl}-1,2-thiazole-4-carboxamide
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C16H18N4O2S2
 1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CP0285447
3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C15H17ClN4O2S2
 1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
CP0109923
3-{[1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C15H17ClN4O2S2
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0136781
3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C14H15ClN4O2S2
 1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
CP0501115
5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-1,2-thiazole-4-carboxamide
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C14H13ClN4O2S2
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0045140
3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C15H15ClN4O2S2
 1
1
IC50 = 118 nM
   TI
   LI
   LO
   TS
CP0502050
3-{[1-(4-chlorophenyl)-2-methylpropyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C16H19ClN4O2S2
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0297089
3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C13H13ClN4O2S2
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0340577
3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-ylamino)-1,2-thiazole-4-carboxamide
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C16H13ClN4OS2
 1
1
IC50 = 344 nM
   TI
   LI
   LO
   TS
CP0110136
3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-3-ylamino)-1,2-thiazole-4-carboxamide
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C16H13ClN4OS2
 1
1
IC50 = 581 nM
   TI
   LI
   LO
   TS
CP0110138
3-{[1-(4-chlorophenyl)butyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C16H19ClN4O2S2
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0146125
3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-2-ylamino)-1,2-thiazole-4-carboxamide
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C16H13ClN4OS2
 1
1
IC50 = 756 nM
   TI
   LI
   LO
   TS
CP0136779
3-{[(1S)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C15H17ClN4O2S2
 1
1
IC50 = 978 nM
   TI
   LI
   LO
   TS
CP0552178
5-[(methylcarbamoyl)amino]-3-(1,2,3,4-tetrahydronaphthalen-1-ylsulfanyl)-1,2-thiazole-4-carboxamide
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C16H18N4O2S2
 1
1
IC50 = 1020 nM
   TI
   LI
   LO
   TS
CP0292059
5-(carbamoylamino)-3-(1,2,3,4-tetrahydronaphthalen-1-ylsulfanyl)-1,2-thiazole-4-carboxamide
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C15H16N4O2S2
 1
1
IC50 = 1170 nM
   TI
   LI
   LO
   TS
CP0275029
3-{[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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C14H12ClF3N4O2S2
 1
1
IC50 = 2870 nM
   TI
   LI
   LO
   TS
CP0369561
3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-methoxypyridin-3-yl)amino]-1,2-thiazole-4-carboxamide
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C17H15ClN4O2S2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0369564
3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamino)-1,2-thiazole-4-carboxamide
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C16H20N4OS2
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Aorta)
Cell Line Name Organism Disease
BAE1 Bos taurus (Bovine) -
HAECT-1 Homo sapiens (Human) -
iHAEC Homo sapiens (Human) -
A-10 Rattus norvegicus (Rat) -
A7r5 Rattus norvegicus (Rat) -