Brief Information of the Compound and Protein
Compound Name
5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-1,2-thiazole-4-carboxamide
    Show/Hide
PubChem ID
CID: 24971408
SID: 163522224
Canonical SMILES
NC(=O)Nc1snc(SC2CCc3cc(Cl)ccc23)c1C(N)=O
    Show/Hide
Compound Formula C14H13ClN4O2S2
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000760 PAE Sus scrofa (Pig)  1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM