Brief Information of the Compound and Protein
Compound Name
3-{[(1S)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide
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PubChem ID
CID: 24971399
Canonical SMILES
CC[C@H](Sc1nsc(NC(=O)NC)c1C(N)=O)c1ccc(Cl)cc1
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Compound Formula C15H17ClN4O2S2
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000760 PAE Sus scrofa (Pig)  1
1
IC50 = 978 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 52 nM