Brief Information of the Compound and Protein
Compound Name
(E)-3-[5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenyl]-2-phenyl-acrylic acid
    Show/Hide
PubChem ID
CID: 10524954
SID: 15550939
Canonical SMILES
OC(=O)C(=C\c1cc(OCc2ccc3OCOc3c2)ccc1C#N)\c1ccccc1
    Show/Hide
Compound Formula C24H17NO5
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000139 A-10 Rattus norvegicus (Rat)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS