Brief Information of the Compound and Protein
Compound Name
(R)-4-[2-Cyano-5-(pyridin-3-ylmethoxy)-phenoxy]-4-o-tolyl-butyric acid
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PubChem ID
CID: 10453733
SID: 15475407
Canonical SMILES
Cc1ccccc1[C@@H](CCC(O)=O)Oc1cc(OCc2cccnc2)ccc1C#N
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Compound Formula C24H22N2O4
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000139 A-10 Rattus norvegicus (Rat)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS