Brief Information of the Compound and Protein
Compound Name
2-[2-cyano-5-[(2,6-dimethylphenyl)methoxy]phenoxy]-2-(2-methylphenyl)acetic acid
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PubChem ID
CID: 10763577
SID: 15801109
Canonical SMILES
Cc1ccccc1C(Oc1cc(OCc2c(C)cccc2C)ccc1C#N)C(O)=O
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Compound Formula C25H23NO4
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000139 A-10 Rattus norvegicus (Rat)  1
1
IC50 = 857 nM
   TI
   LI
   LO
   TS