Brief Information of the Compound and Protein
Compound Name
2-[2-cyano-5-(thiophen-3-ylmethoxy)phenoxy]-2-(2-methoxyphenyl)acetic acid
    Show/Hide
PubChem ID
CID: 10548721
SID: 15575744
Canonical SMILES
COc1ccccc1C(Oc1cc(OCc2ccsc2)ccc1C#N)C(O)=O
    Show/Hide
Compound Formula C21H17NO5S
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000139 A-10 Rattus norvegicus (Rat)  1
1
IC50 = 529 nM
   TI
   LI
   LO
   TS