Brief Information of the Compound and Protein
Compound Name
[2-Cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-o-tolyl-acetic acid
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PubChem ID
CID: 10547407
SID: 15574399
Canonical SMILES
Cc1ccccc1[C@H](Oc1cc(OCc2ccncc2)ccc1C#N)C(=O)O
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Compound Formula C22H18N2O4
Compound Structure
Protein Name
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P26684
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000139 A-10 Rattus norvegicus (Rat)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS