| Compound ID |
Compound Name |
Compound Formula |
|
CP0487466
|
4-[[3-methyl-5-(1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-2-yl]oxymethyl]bicyclo[2.2.2]octan-1-ol
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|
C21H24N4O2
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0487496
|
4-[[3-methyl-5-(1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-2-yl]oxymethyl]bicyclo[2.2.2]octan-1-amine
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|
C21H25N5O
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0572947
|
3-[6-[(4-amino-1-bicyclo[2.2.2]octanyl)methoxy]-5-methylpyridin-3-yl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C21H27N7O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0537790
|
4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methylpyridin-2-yl]oxymethyl]bicyclo[2.2.2]octan-1-amine
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|
C23H29N5O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0564181
|
3-[4-[(4-amino-1-bicyclo[2.2.2]octanyl)methoxy]-3-fluorophenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C21H25FN6O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0466261
|
CHEMBL4783510
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|
C19H23FN6O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0560118
|
3-[4-(2-azaspiro[3.3]heptan-6-ylmethoxy)-3-fluorophenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C19H21FN6O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0533351
|
4-[4-[(4-amino-1-bicyclo[2.2.2]octanyl)methoxy]-3-fluorophenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C21H25FN6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0487497
|
3-[4-[(4-aminocyclohexyl)methoxy]-3-fluorophenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C19H23FN6O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0566216
|
3-[3-fluoro-4-(3-piperidin-4-ylpropoxy)phenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C20H25FN6O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0556153
|
5-[4-[(4-amino-1-bicyclo[2.2.2]octanyl)methoxy]-3-fluorophenyl]-7-methylpyrrolo[2,1-f][1,2,4]triazin-2-amine
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|
C22H26FN5O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0466260
|
3-[3-fluoro-4-(piperidin-4-ylmethoxy)phenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C18H21FN6O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0466262
|
4-[[4-(6-amino-1-methylpyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorophenoxy]methyl]bicyclo[2.2.2]octan-1-ol
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|
C21H24FN5O2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0533350
|
3-[4-[[(1S,5R)-8-azabicyclo[3.2.1]octan-3-yl]methoxy]-3-fluorophenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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|
C20H23FN6O
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
