Brief Information of the Compound and Protein
Compound Name
4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methylpyridin-2-yl]oxymethyl]bicyclo[2.2.2]octan-1-amine
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Canonical SMILES
Cc1cc(-c2cnc(OCC34CCC(N)(CC3)CC4)c(C)c2)c2cnn(C)c2n1
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Compound Formula C23H29N5O
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 2 nM
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