Brief Information of the Compound and Protein
Compound Name
3-[4-[[(1S,5R)-8-azabicyclo[3.2.1]octan-3-yl]methoxy]-3-fluorophenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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Canonical SMILES
Cn1nc(-c2ccc(OCC3C[C@@H]4CC[C@H](C3)N4)c(F)c2)c2cnc(N)nc12
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Compound Formula C20H23FN6O
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 88 nM
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