Brief Information of the Compound and Protein
Compound Name
3-[6-[(4-amino-1-bicyclo[2.2.2]octanyl)methoxy]-5-methylpyridin-3-yl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
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Canonical SMILES
Cc1cc(cnc1OCC12CCC(N)(CC1)CC2)-c1nn(C)c2nc(N)ncc12
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Compound Formula C21H27N7O
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 1 nM
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