Brief Information of the Compound and Protein
Compound Name
4-[[3-methyl-5-(1H-pyrazolo[3,4-b]pyridin-4-yl)pyridin-2-yl]oxymethyl]bicyclo[2.2.2]octan-1-ol
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Canonical SMILES
Cc1cc(cnc1OCC12CCC(O)(CC1)CC2)-c1ccnc2[nH]ncc12
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Compound Formula C21H24N4O2
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 < 1 nM
   TI
   LI
   LO
   TS