Brief Information of the Compound and Protein
Compound Name
3-[3-fluoro-4-(3-piperidin-4-ylpropoxy)phenyl]-1-methylpyrazolo[3,4-d]pyrimidin-6-amine
    Show/Hide
PubChem ID
CID: 129073113
Canonical SMILES
Cn1nc(-c2ccc(OCCCC3CCNCC3)c(F)c2)c2cnc(N)nc12
    Show/Hide
Compound Formula C20H25FN6O
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
>
Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS