| Compound ID |
Compound Name |
Compound Formula |
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CP0852313
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(5S,8S,14S,17S,20S)-20-(2-amino-2-oxoacetamido)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
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C38H52N8O10S
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2
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| 1 |
EC50 = 0.011 nM
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|
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| 2 |
IC50 = 7.9 nM
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CP0385812
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C54H77N13O14S2
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2
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| 1 |
EC50 = 0.012 nM
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| 2 |
IC50 = 4.4 nM
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CP0657579
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(5S,8S,14S,17S,20S,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
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C43H60N8O12S
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2
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| 1 |
EC50 = 0.012 nM
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| 2 |
IC50 = 13 nM
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CP0204318
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(5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-5-yl)methyl)-32-amino-14,17,20-tribenzyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-15-methyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid
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C60H81N13O14S2
|
4
|
| 1 |
EC50 = 0.013 nM
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| 2 |
EC50 = 64 nM
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|
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| 3 |
IC50 = 3 nM
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| 4 |
IC50 = 12 nM
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CP0861325
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-20-ureido-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C37H52N8O9S
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2
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| 1 |
EC50 = 0.013 nM
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| 2 |
IC50 = 39 nM
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CP0657580
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(R)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(oxalyl-amino)-butyric acid
Show/Hide
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C39H53N7O11S
|
2
|
| 1 |
EC50 = 0.014 nM
|
|
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| 2 |
IC50 = 0.51 nM
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CP0473374
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C57H79N15O14S2
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2
|
| 1 |
EC50 = 0.017 nM
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|
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| 2 |
IC50 = 5.9 nM
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CP0852307
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(5S,8S,14S,17S,20R,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C43H60N8O12S
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2
|
| 1 |
EC50 = 0.017 nM
|
|
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| 2 |
IC50 = 68 nM
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CP0869123
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(5S,8S,14S,17S,20R,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
|
C42H58N8O12S
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2
|
| 1 |
EC50 = 0.017 nM
|
|
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| 2 |
IC50 = 55 nM
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CP0845717
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(5S,8S,14S,17S,20S,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C42H58N8O12S
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2
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| 1 |
EC50 = 0.018 nM
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| 2 |
IC50 = 73 nM
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CP0867814
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(5S,8S,14S,17S,20R,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C43H60N8O12S
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2
|
| 1 |
EC50 = 0.018 nM
|
|
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| 2 |
IC50 = 37 nM
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CP0767143
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(S)-5-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-5-(3-carboxy-propionylamino)-pentanoic acid
Show/Hide
|
C42H59N7O11S
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2
|
| 1 |
EC50 = 0.019 nM
|
|
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| 2 |
IC50 = 9.9 nM
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CP0683920
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(R)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(oxalyl-amino)-succinamic acid
Show/Hide
|
C38H51N7O11S
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2
|
| 1 |
EC50 = 0.022 nM
|
|
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| 2 |
IC50 = 3.5 nM
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CP0385807
|
(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
Show/Hide
|
C56H79N13O16S2
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2
|
| 1 |
EC50 = 0.024 nM
|
|
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| 2 |
IC50 = 7.5 nM
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CP0852314
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(5S,8S,14S,17S,20R,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
|
C42H58N8O12S
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2
|
| 1 |
EC50 = 0.024 nM
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|
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| 2 |
IC50 = 83 nM
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CP0462398
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C57H84N14O14S2
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2
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| 1 |
EC50 = 0.026 nM
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| 2 |
IC50 = 11 nM
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CP0845718
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(R)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
|
C40H55N7O11S
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2
|
| 1 |
EC50 = 0.029 nM
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|
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| 2 |
IC50 = 16 nM
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CP0767142
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(S)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(3-carboxy-propionylamino)-butyric acid
Show/Hide
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C41H57N7O11S
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2
|
| 1 |
EC50 = 0.03 nM
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| 2 |
IC50 = 6.1 nM
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CP0845715
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(5S,8S,14S,17S,20S,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
|
C42H58N8O12S
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2
|
| 1 |
EC50 = 0.031 nM
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| 2 |
IC50 = 68 nM
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CP0420578
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C56H81N13O14S3
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2
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| 1 |
EC50 = 0.032 nM
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| 2 |
IC50 = 1.7 nM
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CP0845712
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C42H56N8O11S
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2
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| 1 |
EC50 = 0.033 nM
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| 2 |
IC50 = 123 nM
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CP0422539
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C55H78N14O15S2
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2
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| 1 |
EC50 = 0.036 nM
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| 2 |
IC50 = 18 nM
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CP0489912
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C53H75N13O14S2
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2
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| 1 |
EC50 = 0.036 nM
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| 2 |
IC50 = 13 nM
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CP0447546
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(3S)-3-amino-4-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C64H97N15O18S
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2
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| 1 |
EC50 = 0.038 nM
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| 2 |
IC50 = 13 nM
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CP0385816
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C54H77N13O15S2
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2
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| 1 |
EC50 = 0.04 nM
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| 2 |
IC50 = 3.6 nM
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CP0473373
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C55H77N13O16S2
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2
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| 1 |
EC50 = 0.04 nM
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| 2 |
IC50 = 38 nM
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CP0415029
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C56H79N13O14S2
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2
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| 1 |
EC50 = 0.041 nM
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| 2 |
IC50 = 45 nM
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CP0852310
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C40H55N7O12S
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2
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| 1 |
EC50 = 0.041 nM
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| 2 |
IC50 = 28 nM
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CP0385810
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C56H80N14O15S2
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2
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| 1 |
EC50 = 0.043 nM
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| 2 |
IC50 = 4.6 nM
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CP0852311
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-20-(3-hydroxyureido)-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C37H52N8O10S
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2
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| 1 |
EC50 = 0.043 nM
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| 2 |
IC50 = 10 nM
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CP0427097
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C55H79N13O15S2
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2
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| 1 |
EC50 = 0.046 nM
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| 2 |
IC50 = 4.3 nM
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CP0894537
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(S)-N-((S)-1-{[(1S,2S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-butyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
|
C37H57N7O11S
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2
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| 1 |
EC50 = 0.05 nM
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| 2 |
IC50 = 91 nM
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CP0385805
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C57H83N13O14S2
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2
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| 1 |
EC50 = 0.051 nM
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| 2 |
IC50 = 6.9 nM
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CP0885149
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(5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidazol-5-yl)methyl)-32-amino-14,17-dibenzyl-20-sec-butyl-5-carbamoyl-23-(carboxymethyl)-8-isobutyl-15-methyl-29-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-2-thia-6,9,12,15,18,21,24,27,30-nonaazatetratriacontan-34-oic acid
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C57H83N13O14S2
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2
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| 1 |
EC50 = 0.06 nM
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| 2 |
IC50 = 4 nM
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CP0852315
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(5S,8S,14S,17S,20S,23S)-23-amino-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
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C40H56N8O11S
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2
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| 1 |
EC50 = 0.063 nM
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| 2 |
IC50 = 175 nM
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CP0848393
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-propyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
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C36H55N7O11S
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2
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| 1 |
EC50 = 0.064 nM
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| 2 |
IC50 = 104 nM
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CP0385813
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C56H81N13O14S2
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2
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| 1 |
EC50 = 0.065 nM
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| 2 |
IC50 = 1.5 nM
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CP0427101
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(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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C58H85N13O15S
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2
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| 1 |
EC50 = 0.071 nM
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| 2 |
IC50 = 7 nM
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CP0447541
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C60H81N13O15S2
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2
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| 1 |
EC50 = 0.072 nM
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| 2 |
IC50 = 1.5 nM
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CP0462396
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(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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C59H85N13O17S
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2
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| 1 |
EC50 = 0.078 nM
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| 2 |
IC50 = 5.5 nM
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CP0432196
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(4S)-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-1-[(2S)-4-amino-4-oxo-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]amino]-5-oxopentanoic acid
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C55H81N13O17S
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2
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| 1 |
EC50 = 0.079 nM
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| 2 |
IC50 = 53 nM
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CP0385806
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C57H84N16O14S2
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2
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| 1 |
EC50 = 0.08 nM
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| 2 |
IC50 = 2.5 nM
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CP0432195
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(3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-[[(2S)-1-[(2S)-4-amino-4-oxo-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoic acid
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C59H81N13O17S
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2
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| 1 |
EC50 = 0.083 nM
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| 2 |
IC50 = 19 nM
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CP0695551
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(oxalyl-amino)-succinamic acid
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C38H51N7O11S
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2
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| 1 |
EC50 = 0.083 nM
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| 2 |
IC50 = 3.6 nM
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CP0850458
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(R)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(3-carboxy-propionylamino)-butyric acid
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C41H57N7O11S
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2
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| 1 |
EC50 = 0.084 nM
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| 2 |
IC50 = 24 nM
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CP0483896
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(3S)-3-amino-4-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C63H94N14O19S
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2
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| 1 |
EC50 = 0.085 nM
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| 2 |
IC50 = 27 nM
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CP0385809
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(3S)-3-amino-4-[[(2S,3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C50H71N11O17S
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2
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| 1 |
EC50 = 0.11 nM
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| 2 |
IC50 = 81 nM
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CP0474065
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UPEROLEIN
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C56H79N13O15S
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2
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| 1 |
EC50 = 0.12 nM
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| 2 |
IC50 = 82 nM
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CP0432225
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(3S)-3-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
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C58H81N13O16S
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2
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| 1 |
EC50 = 0.13 nM
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| 2 |
IC50 = 17 nM
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CP0489911
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(3S)-3-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-3-carboxy-2-[[(2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
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C57H79N13O17S
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2
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| 1 |
EC50 = 0.15 nM
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| 2 |
IC50 = 54 nM
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CP0462395
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Asp-Val-Pro-Lys-Ser-Asp-Gln-Phe-Val-Gly-Leu-Met-NH2
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C59H94N14O19S
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2
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| 1 |
EC50 = 0.21 nM
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| 2 |
IC50 = 100 nM
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CP0169958
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(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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C54H85N13O15S
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4
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| 1 |
EC50 = 0.22 nM
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| 2 |
EC50 = 5.7 nM
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| 3 |
EC50 = 6.6 nM
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| 4 |
IC50 = 96 nM
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CP0432188
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(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C62H82N14O14S2
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2
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| 1 |
EC50 = 0.28 nM
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| 2 |
IC50 = 1.8 nM
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CP0432189
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(3S)-3-amino-4-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C58H92N14O19S
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2
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| 1 |
EC50 = 0.47 nM
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| 2 |
IC50 = 89 nM
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CP0432191
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(4S)-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-1-[(2S)-4-amino-4-oxo-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]butanoyl]pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]amino]-5-oxopentanoic acid
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C59H81N13O18S
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2
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| 1 |
EC50 = 1.38 nM
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| 2 |
IC50 = 710 nM
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CP0516889
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3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(thiophen-2-yl)quinoline-4-carboxamide
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C24H22N2O2S2
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1
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| 1 |
EC50 = 1.7 nM
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CP0371564
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3-((R)-methylsulfinylmethyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C27H26N2O2S
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1
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| 1 |
EC50 = 1.8 nM
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CP0487303
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3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(thiophen-3-yl)quinoline-4-carboxamide
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C24H22N2O2S2
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1
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| 1 |
EC50 = 1.8 nM
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CP0461745
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(S)-3-(methylsulfonylmethyl)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
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C27H26N2O3S
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1
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| 1 |
EC50 = 2.5 nM
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CP0088817
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C40H55N7O11S
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6
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| 1 |
EC50 = 3 nM
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| 2 |
EC50 = 11 nM
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| 3 |
IC50 = 21 nM
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| 4 |
IC50 = 29 nM
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| 5 |
IC50 = 56 nM
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| 6 |
Ki = 3.162 nM
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CP0494831
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3-(2-(methylsulfinyl)ethyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C28H28N2O2S
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1
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| 1 |
EC50 = 3.3 nM
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CP0913425
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[Glp-Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2]
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C57H82N14O16S
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2
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| 1 |
EC50 = 3.36 nM
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| 2 |
IC50 = 1550 nM
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CP0500539
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7-methyl-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C27H26N2O2S
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1
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| 1 |
EC50 = 3.6 nM
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CP0371563
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3-((S)-methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C26H24N2O2S
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1
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| 1 |
EC50 = 3.7 nM
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CP0473375
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(3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoic acid
Show/Hide
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C62H94N16O15S
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2
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| 1 |
EC50 = 5.04 nM
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| 2 |
IC50 = 31 nM
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CP0516580
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7-bromo-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C26H23BrN2O2S
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1
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| 1 |
EC50 = 5.1 nM
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CP0057489
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3-((S)-methylsulfinylmethyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
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C27H26N2O2S
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1
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| 1 |
EC50 = 5.3 nM
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CP0516579
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3-(ethylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C27H26N2O2S
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1
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| 1 |
EC50 = 6.9 nM
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CP0520227
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7-chloro-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C26H23ClN2O2S
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1
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| 1 |
EC50 = 7.7 nM
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CP0522573
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8-fluoro-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C26H23FN2O2S
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1
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| 1 |
EC50 = 8.2 nM
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CP0427103
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BUFOKININ
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C62H95N17O15S
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2
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| 1 |
EC50 = 10.73 nM
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| 2 |
IC50 = 2990 nM
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CP0427104
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SIALOKININ II
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C51H76N12O16S
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2
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| 1 |
EC50 = 10.88 nM
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| 2 |
IC50 = 1930 nM
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CP0399922
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3-(2-(dimethylamino)-2-oxoethylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
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C29H29N3O3S
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1
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| 1 |
EC50 = 12 nM
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CP0409972
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7-fluoro-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
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C26H23FN2O2S
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1
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| 1 |
EC50 = 13 nM
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CP0541982
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(S)-3-(methylsulfonyl)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
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C26H24N2O3S
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1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0469161
|
N-[(S)-cyclopropyl(phenyl)methyl]-3-methylsulfinyl-2-phenylquinoline-4-carboxamide
Show/Hide
|
C27H24N2O2S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0487304
|
3-(isopropylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C28H28N2O2S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0520228
|
3-(methylsulfinyl)-2-phenyl-N-(1-phenylcyclopropyl)quinoline-4-carboxamide
Show/Hide
|
C26H22N2O2S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0324251
|
(3S)-4-[[(2S)-1-[[(2S)-1-[[(E,4R)-4-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]-6-methylhept-2-enyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(3-carboxypropanoylamino)-4-oxobutanoic acid
Show/Hide
|
C41H56N6O10S
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
IC50 = 56 nM
|
|
|
|
CP0501441
|
2-(3-fluorophenyl)-3-(methylsulfinyl)-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C26H23FN2O2S
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0494830
|
(S)-3-(methylthiomethyl)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C27H26N2OS
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0500538
|
(S)-3-(methylthio)-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C26H24N2OS
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0501442
|
7-ethoxy-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C28H28N2O3S
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0516582
|
3-(methylsulfinyl)-2-phenyl-N-(1-phenylcyclobutyl)quinoline-4-carboxamide
Show/Hide
|
C27H24N2O2S
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0502078
|
2-(4-fluorophenyl)-3-(methylsulfinyl)-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C26H23FN2O2S
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0425623
|
3-(methylsulfinyl)-2-phenyl-N-((S)-1-(pyridin-3-yl)propyl)quinoline-4-carboxamide
Show/Hide
|
C25H23N3O2S
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0426576
|
2-(2-fluorophenyl)-3-(methylsulfinyl)-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C26H23FN2O2S
|
1
|
| 1 |
EC50 = 81 nM
|
|
|
|
CP0516581
|
7-((dimethylamino)methyl)-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C29H31N3O2S
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0386891
|
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C45H60N8O9S
|
2
|
| 1 |
EC50 = 91 nM
|
|
|
| 2 |
IC50 = 59 nM
|
|
|
|
CP0550798
|
(3S)-4-[[(2S)-1-[[(2S)-1-[[2-amino-2-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]iminoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(3-carboxypropanoylamino)-4-oxobutanoic acid
Show/Hide
|
C40H56N8O10S
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
IC50 = 360 nM
|
|
|
|
CP0522571
|
3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(thiazol-4-yl)quinoline-4-carboxamide
Show/Hide
|
C23H21N3O2S2
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0469160
|
7-(dimethylamino)-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C28H29N3O2S
|
1
|
| 1 |
EC50 = 212 nM
|
|
|
|
CP0469159
|
3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(thiazol-5-yl)quinoline-4-carboxamide
Show/Hide
|
C23H21N3O2S2
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0409444
|
(2S)-N-[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]-methylamino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanamide
Show/Hide
|
C41H55N7O6S
|
2
|
| 1 |
EC50 = 240 nM
|
|
|
| 2 |
IC50 = 2900 nM
|
|
|
|
CP0910305
|
(5S,8S,14S,17S,20S,23S)-23-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)-14,17,20-tribenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
|
C51H67N11O10S
|
2
|
| 1 |
EC50 = 280 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
|
CP0847510
|
(5S,8S,14S,17S,20S,23S)-23-((S)-2-((S)-2-amino-4-(methylthio)butanamido)-3-(1H-imidazol-5-yl)propanamido)-14,17,20-tribenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
|
C56H76N12O11S2
|
2
|
| 1 |
EC50 = 330 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0411323
|
(2S)-N-[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]-methylamino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanamide
Show/Hide
|
C32H46N6O5S
|
2
|
| 1 |
EC50 = 350 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
|
CP0383400
|
(3S)-4-[[(2S)-1-[[(2S)-1-[[2-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]imino-2-(hydroxyamino)ethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(3-carboxypropanoylamino)-4-oxobutanoic acid
Show/Hide
|
C40H56N8O11S
|
2
|
| 1 |
EC50 = 370 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0502079
|
3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
Show/Hide
|
C25H23N3O2S
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0518132
|
(3S)-4-[[(2S)-1-[[(2S)-1-[[(4S)-4-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]-6-methylheptyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(3-carboxypropanoylamino)-4-oxobutanoic acid
Show/Hide
|
C41H58N6O10S
|
2
|
| 1 |
EC50 = 920 nM
|
|
|
| 2 |
IC50 = 19000 nM
|
|
|
|
CP0399920
|
3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(pyridin-2-yl)quinoline-4-carboxamide
Show/Hide
|
C25H23N3O2S
|
1
|
| 1 |
EC50 = 1120 nM
|
|
|
|
CP0520226
|
8-methyl-3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C27H26N2O2S
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0490606
|
(3S)-4-[[(2S)-1-[[(2S)-1-[[(E)-4-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]-6-methylhept-3-enyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(3-carboxypropanoylamino)-4-oxobutanoic acid
Show/Hide
|
C41H56N6O10S
|
2
|
| 1 |
EC50 = 1900 nM
|
|
|
| 2 |
IC50 = 13000 nM
|
|
|
|
CP0522572
|
3-(methylsulfinyl)-N-((S)-1-phenylpropyl)-2-(1H-pyrazol-3-yl)quinoline-4-carboxamide
Show/Hide
|
C23H22N4O2S
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0490605
|
(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]-methylamino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
|
C32H45N5O6S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0518131
|
2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]-methylamino]-3-phenylpropanoyl]amino]acetic acid
Show/Hide
|
C21H25N3O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0074738
|
(S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
Show/Hide
|
C35H41Cl2N3O2
|
3
|
| 1 |
IC50 = 0.21 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
| 3 |
Ki = 1.585 nM
|
|
|
|
CP0751077
|
(S)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(oxalyl-amino)-butyric acid
Show/Hide
|
C39H53N7O11S
|
1
|
| 1 |
IC50 = 0.43 nM
|
|
|
|
CP0421214
|
methyl N-[[3-[[4-(benzenesulfonyl)piperazin-1-yl]methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C35H33N5O5S
|
1
|
| 1 |
IC50 = 0.72 nM
|
|
|
|
CP0464721
|
3-methoxy-N',N',2-triphenylquinoline-4-carbohydrazide
Show/Hide
|
C29H23N3O2
|
1
|
| 1 |
IC50 = 0.85 nM
|
|
|
|
CP0683921
|
(S)-5-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-5-(oxalyl-amino)-pentanoic acid
Show/Hide
|
C40H55N7O11S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0381798
|
methyl N-[[8-fluoro-3-[[4-(1-methylcyclohexyl)piperazin-1-yl]methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C36H40FN5O3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0432590
|
methyl N-[[3-[(4-benzylpiperazin-1-yl)methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C36H35N5O3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0459454
|
AZD-2624
Show/Hide
|
C26H25N3O3S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0394060
|
methyl N-phenyl-N-[[2-phenyl-3-[[4-(thian-4-yl)piperazin-1-yl]methyl]quinoline-4-carbonyl]amino]carbamate
Show/Hide
|
C34H37N5O3S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0421218
|
methyl N-[[3-[(4-cyclohexylpiperazin-1-yl)methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C35H39N5O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0074739
|
[(8R)-8-methyl-3-(2-propan-2-yl-1,3-oxazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C23H23N5O2S
|
3
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3.981 nM
|
|
|
| 3 |
Ki = 3.162 nM
|
|
|
|
CP0114969
|
[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C20H18N6OS2
|
3
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3.981 nM
|
|
|
| 3 |
Ki = 3.162 nM
|
|
|
|
CP0114970
|
(S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide
Show/Hide
|
C25H22N2O2
|
5
|
| 1 |
IC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 8.4 nM
|
|
|
| 3 |
Ki = 1 nM
|
|
|
| 4 |
Ki = 7.943 nM
|
|
|
| 5 |
Ki = 254 nM
|
|
|
|
CP0254346
|
methyl N-[[3-[(4-tert-butylpiperazin-1-yl)methyl]-8-fluoro-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C33H36FN5O3
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0531617
|
BDBM272562
Show/Hide
|
C22H22N6OS2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0553577
|
US10065961, Compound 7
Show/Hide
|
C22H19N5OS2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0567105
|
US10065961, Compound 5
Show/Hide
|
C22H21N5OS2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0432591
|
methyl N-[[3-[[4-(oxan-4-yl)piperazin-1-yl]methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C34H37N5O4
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0441792
|
methyl N-[[8-fluoro-3-[[4-(oxan-4-yl)piperazin-1-yl]methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C34H36FN5O4
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0453581
|
methyl N-[[8-fluoro-3-[[4-(4-methyloxan-4-yl)piperazin-1-yl]methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C35H38FN5O4
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0459642
|
2-(2-hydroxyphenyl)-3-(methanesulfonamido)-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C26H25N3O4S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0115022
|
[(8R)-8-methyl-3-(2-propan-2-yl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C23H23N5OS2
|
2
|
| 1 |
IC50 = 3.981 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0501133
|
methyl N-[(8-fluoro-3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0845710
|
(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-20-(2-methoxy-2-oxoacetamido)-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
|
C39H53N7O11S
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0514852
|
2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-carboxamide
Show/Hide
|
C24H21N3O
|
2
|
| 1 |
IC50 = 5.2 nM
|
|
|
| 2 |
IC50 = 900 nM
|
|
|
|
CP0871268
|
(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-20-(sulfamoylamino)-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
|
C36H52N8O10S2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0420678
|
2-phenyl-N-[(1S)-1-phenylpropyl]-3-sulfanylquinoline-4-carboxamide
Show/Hide
|
C25H22N2OS
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0381800
|
methyl N-[[3-[[1-(oxan-4-yl)piperidin-4-yl]methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C35H38N4O4
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0432589
|
methyl N-[[8-fluoro-2-phenyl-3-[(4-propan-2-ylpiperazin-1-yl)methyl]quinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C32H34FN5O3
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0453583
|
methyl N-phenyl-N-[[2-phenyl-3-[(4-propan-2-ylpiperazin-1-yl)methyl]quinoline-4-carbonyl]amino]carbamate
Show/Hide
|
C32H35N5O3
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0566921
|
3-hydroxy-2-(2-hydroxyphenyl)-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C25H22N2O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0126344
|
(4-fluorophenyl)-[(8R)-8-methyl-3-[3-(trifluoromethyl)-1,2,4-thiadiazol-5-yl]-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C16H12F4N6OS
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0044631
|
(S)-3-methyl-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C26H24N2O
|
2
|
| 1 |
IC50 = 6.7 nM
|
|
|
| 2 |
Ki = 4.2 nM
|
|
|
|
CP0402314
|
[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-1-[7-(carbamoylamino)heptylamino]-3-(2,3-difluorophenyl)-2-methyl-1-oxopropan-2-yl]carbamate
Show/Hide
|
C29H40F2N4O4
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 7.3 nM
|
|
|
|
CP0451925
|
US10065961, Compound 17
Show/Hide
|
C22H22N6OS2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0532553
|
US10065961, Compound 8
Show/Hide
|
C24H21N5OS
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0453580
|
methyl N-[[3-[(4-acetylpiperazin-1-yl)methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C31H31N5O4
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0503334
|
methyl N-(3-fluorophenyl)-N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]carbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0649061
|
(5S,8S,14S,17S,20S,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
|
C43H60N8O12S
|
1
|
| 1 |
IC50 = 7.7 nM
|
|
|
|
CP0115023
|
[(8R)-8-methyl-3-(4-methyl-1,3-thiazol-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C21H19N5OS2
|
3
|
| 1 |
IC50 = 7.943 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
| 3 |
Ki = 6.31 nM
|
|
|
|
CP0485291
|
methyl N-[(3-methyl-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H21N3O3
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0058365
|
methyl N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H21N3O4
|
3
|
| 1 |
IC50 = 8.8 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
| 3 |
IC50 = 30 nM
|
|
|
|
CP0477025
|
US10065961, Compound 15
Show/Hide
|
C23H21N5O2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0074736
|
(NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2
Show/Hide
|
C55H79N13O14S2
|
4
|
| 1 |
IC50 = 9.7 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
| 3 |
IC50 = 76 nM
|
|
|
| 4 |
Ki = 0.7943 nM
|
|
|
|
CP0408365
|
methyl N-[(3-amino-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C24H20N4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0088851
|
[(8R)-8-methyl-3-(6-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C23H21N5OS
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
| 3 |
Ki = 10 nM
|
|
|
|
CP0451922
|
US10065961, Compound 18
Show/Hide
|
C22H21N5OS2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0567106
|
US10065961, Compound 6
Show/Hide
|
C24H23N5OS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0381796
|
methyl N-[[3-[2-(dimethylamino)ethoxy]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C28H28N4O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0408422
|
methyl N-[(5-fluoro-3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0451924
|
US10065961, Compound 20
Show/Hide
|
C23H21N5OS
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0394061
|
methyl N-[[3-[1-(oxan-4-yl)piperidin-4-yl]oxy-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C34H36N4O5
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0480884
|
US10065961, Compound 26
Show/Hide
|
C21H19N5O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0074734
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(2-phenyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C22H18FN5OS
|
2
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0088854
|
[(8R)-8-methyl-3-(2-methyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C21H19N5OS2
|
3
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
| 3 |
Ki = 12.59 nM
|
|
|
|
CP0409470
|
tert-butyl N-[(2S)-1-[[(2R)-1-[7-(carbamoylamino)heptylamino]-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C32H47N5O5
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0373658
|
[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-1-[7-(carbamoylamino)heptylamino]-3-(2-fluorophenyl)-2-methyl-1-oxopropan-2-yl]carbamate
Show/Hide
|
C29H41FN4O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0453636
|
N'-ethyl-3-methoxy-N',2-diphenylquinoline-4-carbohydrazide
Show/Hide
|
C25H23N3O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0408363
|
methyl N-[[3-(1-tert-butylpiperidin-4-yl)oxy-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C33H36N4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0441791
|
methyl N-[[3-[(4-methylpiperazin-1-yl)methyl]-2-phenylquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C30H31N5O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0402544
|
tert-butyl N-[(2S)-1-[[(2R)-2-methyl-1-[[9-(methylamino)-9-oxononyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C34H50N4O5
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0507701
|
US10065961, Compound 29
Show/Hide
|
C25H23N5O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0512585
|
US10065961, Compound 31
Show/Hide
|
C22H19N5O2S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0553578
|
US10065961, Compound 9
Show/Hide
|
C21H17N5OS2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0074740
|
[(8R)-3-[2-(2,4-difluorophenyl)-1,3-thiazol-4-yl]-8-methyl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C26H19F2N5OS2
|
2
|
| 1 |
IC50 = 19.95 nM
|
|
|
| 2 |
Ki = 1.995 nM
|
|
|
|
CP0115020
|
[(8R)-8-methyl-3-(6-methylpyrazin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C22H20N6OS
|
2
|
| 1 |
IC50 = 19.95 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0112422
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C16H15FN6OS
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0428958
|
US10065961, Compound 10
Show/Hide
|
C23H19N5OS
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0507881
|
US10065961, Compound 22
Show/Hide
|
C22H21N5OS2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0503333
|
methyl N-[[2-(3-fluorophenyl)-3-methoxyquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0552236
|
3-methoxy-N',2-diphenyl-N'-propionylquinoline-4-carbohydrazide
Show/Hide
|
C26H23N3O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0421217
|
methyl N-[[2-(4-fluorophenyl)-3-methoxyquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0403185
|
3-azido-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C25H21N5O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0074735
|
[(8R)-8-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C20H18N6O2S
|
3
|
| 1 |
IC50 = 25.12 nM
|
|
|
| 2 |
IC50 = 33 nM
|
|
|
| 3 |
Ki = 25.12 nM
|
|
|
|
CP0515531
|
(S)-2-[2-((S)-2-{(S)-2-[2-(4-Hydroxy-phenyl)-acetylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoic acid ((S)-1-carbamoyl-3-methylsulfanyl-propyl)-amide
Show/Hide
|
C39H50N6O7S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0453466
|
tert-butyl N-[(2S)-1-[[(2R)-1-[[9-(dimethylamino)-9-oxononyl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C35H52N4O5
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0454509
|
tert-butyl N-[(2S)-1-[[(2R)-2-methyl-1-(8-methylsulfonyloctylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H49N3O6S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0503332
|
methyl N-[(7-fluoro-3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0445185
|
US10065961, Compound 2
Show/Hide
|
C23H21N5OS
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0518492
|
US10065961, Compound 16
Show/Hide
|
C22H21N5OS2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0463377
|
tert-butyl N-[(2S)-1-[[(2R)-1-[7-(methanesulfonamido)heptylamino]-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C32H48N4O6S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0212153
|
(4-chlorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C16H15ClN6OS
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0522376
|
3-methoxy-N',2-diphenylquinoline-4-carbohydrazide
Show/Hide
|
C23H19N3O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0408364
|
methyl N-(4-fluorophenyl)-N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]carbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0556277
|
US10065961, Compound 21
Show/Hide
|
C22H19N5OS
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0431082
|
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-ethyl)-amide
Show/Hide
|
C24H20N2O
|
4
|
| 1 |
IC50 = 33.5 nM
|
|
|
| 2 |
IC50 = 2200 nM
|
|
|
| 3 |
Ki = 251.19 nM
|
|
|
| 4 |
Ki = 264 nM
|
|
|
|
CP0408361
|
methyl N-phenyl-N-[[2-phenyl-3-(piperazin-1-ylmethyl)quinoline-4-carbonyl]amino]carbamate
Show/Hide
|
C29H29N5O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0867813
|
(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-20-(hydrazinecarboxamido)-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
|
C37H53N9O9S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0494938
|
US10065961, Compound 11
Show/Hide
|
C21H19N5O2S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0474063
|
(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C55H85N13O17S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0439411
|
methyl N-[[8-fluoro-2-phenyl-3-(piperazin-1-ylmethyl)quinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C29H28FN5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0531618
|
US10065961, Compound 28
Show/Hide
|
C22H22N6OS
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0439398
|
methyl N-[(6-fluoro-3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0504687
|
tert-butyl N-[(2S)-1-[[(2R)-1-[(9-amino-9-oxononyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H48N4O5
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0445282
|
((R)-1-{(R)-1-[4-(4-Hydroxy-phenyl)-butylcarbamoyl]-1-methyl-2-phenyl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester
Show/Hide
|
C34H43N3O5
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0460903
|
tert-butyl N-[(2S)-1-[[(2R)-1-[(9-amino-9-oxononyl)amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H48N4O5
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0503331
|
methyl N-[(3-hydroxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C24H19N3O4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0126339
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C18H19FN6O2
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0377158
|
tert-butyl N-[(2S)-1-[[(2R)-1-(8-hydroxyoctylamino)-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C32H47N3O5
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0507580
|
tert-butyl N-[(2S)-1-[[(2R)-1-(8-hydroxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C32H47N3O5
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0509590
|
(4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(trifluoromethyl)phenyl)-1H-pyrazol-5-yl)methanone
Show/Hide
|
C22H21F3N4O2
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
Ki = 120 nM
|
|
|
|
CP0461232
|
[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-1-[7-(carbamoylamino)heptylamino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C29H42N4O4
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 57 nM
|
|
|
|
CP0474047
|
3-hydroxy-7-methoxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0567107
|
US10065961, Compound 14
Show/Hide
|
C22H21N5O2S
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0428956
|
US10065961, Compound 4
Show/Hide
|
C20H14F3N5OS2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0453582
|
methyl N-phenyl-N-[[2-phenyl-3-(piperidin-4-ylmethyl)quinoline-4-carbonyl]amino]carbamate
Show/Hide
|
C30H30N4O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0556278
|
US9475814, 27
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0448301
|
[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-1-(8-hydroxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C29H42N2O4
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0501132
|
methyl N-(2-fluorophenyl)-N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]carbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0554684
|
3-methoxy-N'-methyl-N',2-diphenylquinoline-4-carbohydrazide
Show/Hide
|
C24H21N3O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0565767
|
US10065961, Compound 12
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0467293
|
ethyl N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C26H23N3O4
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0503317
|
(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-(3-fluorobenzyloxy)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C27H24ClFN4O2
|
2
|
| 1 |
IC50 = 60 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
|
CP0257056
|
[(8R)-8-methyl-3-[2-(trifluoromethyl)-1,3-thiazol-4-yl]-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C21H16F3N5OS2
|
2
|
| 1 |
IC50 = 63.1 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0147959
|
[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-phenylmethanone
Show/Hide
|
C16H16N6OS
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0453478
|
((S)-1-{(R)-1-[2-(4-Carbamoylmethoxy-phenyl)-ethylcarbamoyl]-1-methyl-2-phenyl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester
Show/Hide
|
C34H42N4O6
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0395420
|
[(1R)-2-methyl-1-phenylpropyl] N-[(2R)-2-methyl-1-oxo-3-phenyl-1-[[(1S)-1-phenylethyl]amino]propan-2-yl]carbamate
Show/Hide
|
C29H34N2O3
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0088852
|
[3-(2-methyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C20H17N5OS2
|
3
|
| 1 |
IC50 = 79.43 nM
|
|
|
| 2 |
IC50 = 83 nM
|
|
|
| 3 |
Ki = 79.43 nM
|
|
|
|
CP0415194
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(6-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C19H18FN5O
|
2
|
| 1 |
IC50 = 79.43 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0126108
|
(4-fluorophenyl)-[(8R)-8-(2-hydroxyethyl)-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C17H17FN6O2S
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0426048
|
2-(2-(4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl)piperazin-1-yl)phenoxy)acetamide
Show/Hide
|
C22H22ClN5O3
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
Ki = 240 nM
|
|
|
|
CP0419498
|
methyl N-phenyl-N-[(2-phenylquinoline-4-carbonyl)amino]carbamate
Show/Hide
|
C24H19N3O3
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0503316
|
tert-butyl N-[(2S)-1-[[1-(8-hydroxyoctylamino)-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C32H47N3O5
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0460745
|
tert-butyl N-[(2S)-1-[[1-(8-hydroxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C32H47N3O5
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0503318
|
(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)-3,3-dimethylpiperazin-1-yl)methanone
Show/Hide
|
C23H25ClN4O2
|
2
|
| 1 |
IC50 = 93 nM
|
|
|
| 2 |
Ki = 240 nM
|
|
|
|
CP0528371
|
tert-butyl N-[(2S)-1-[[1-(8-methoxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H49N3O5
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0509839
|
tert-butyl N-[(2S)-1-[[1-(8-methoxyoctylamino)-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H49N3O5
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0511349
|
tert-butyl N-[(2S)-1-[[1-(9-hydroxynonylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H49N3O5
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0425427
|
methyl N-[[2-(2-fluorophenyl)-3-methoxyquinoline-4-carbonyl]amino]-N-phenylcarbamate
Show/Hide
|
C25H20FN3O4
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0435232
|
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydropyrimidin-2(1H)-one
Show/Hide
|
C24H21N3O5
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0532671
|
tert-butyl N-[(2S)-1-[[1-(7-hydroxyheptylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C31H45N3O5
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0451136
|
2-[2-(2-{2-[2-(4-Hydroxy-phenyl)-acetylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoic acid (1-carbamoyl-3-methylsulfanyl-propyl)-amide
Show/Hide
|
C39H50N6O7S
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0539525
|
((S)-1-{(R)-1-[2-(2-Carbamoylmethoxy-phenyl)-ethylcarbamoyl]-1-methyl-2-phenyl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester
Show/Hide
|
C34H42N4O6
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0142899
|
(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxybenzyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23ClN4O2
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
Ki = 490 nM
|
|
|
|
CP0160753
|
(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C21H21ClN4O2
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
Ki = 250 nM
|
|
|
|
CP0462973
|
(4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(trifluoromethoxy)phenyl)-1H-pyrazol-5-yl)methanone
Show/Hide
|
C22H21F3N4O3
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
Ki = 310 nM
|
|
|
|
CP0317460
|
5-(((2S,3S)-2-(3,5-bis(trifluoromethyl)benzyloxy)-3-phenylmorpholino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C22H20F6N4O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0459641
|
3-[(4-methoxyphenyl)methylsulfanyl]-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C33H30N2O2S
|
1
|
| 1 |
IC50 = 154 nM
|
|
|
|
CP0115021
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(2-methyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C17H16FN5OS
|
2
|
| 1 |
IC50 = 158.49 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0120396
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C16H15FN6O2
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0215350
|
(4-fluorophenyl)-[3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C15H13FN6OS
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0453579
|
methyl N-phenyl-N-[[2-phenyl-3-(piperidin-1-ylmethyl)quinoline-4-carbonyl]amino]carbamate
Show/Hide
|
C30H30N4O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0395465
|
tert-butyl N-[(2S)-1-[[2-methyl-1-oxo-3-phenyl-1-(4-phenylbutylamino)propan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C34H43N3O4
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0142900
|
(5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23ClN4O2
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
Ki = 370 nM
|
|
|
|
CP0142901
|
(3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23ClN4O2
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
Ki = 540 nM
|
|
|
|
CP0462970
|
(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-ethylphenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23ClN4O
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
Ki = 190 nM
|
|
|
|
CP0496725
|
2-methylpropyl N-[(3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C28H27N3O4
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0478761
|
(S)-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)-2-methylpiperazin-1-yl)methanone
Show/Hide
|
C22H23ClN4O2
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
Ki = 370 nM
|
|
|
|
CP0499996
|
(3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C21H20Cl2N4O2
|
2
|
| 1 |
IC50 = 205 nM
|
|
|
| 2 |
Ki = 260 nM
|
|
|
|
CP0460388
|
4-(5-(4-(2-methoxyphenyl)piperazine-1-carbonyl)-1H-pyrazol-3-yl)benzonitrile
Show/Hide
|
C22H21N5O2
|
2
|
| 1 |
IC50 = 208 nM
|
|
|
| 2 |
Ki = 700 nM
|
|
|
|
CP0421352
|
N'-acetyl-3-methoxy-N',2-diphenylquinoline-4-carbohydrazide
Show/Hide
|
C25H21N3O3
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0480707
|
8-[2-((S)-2-tert-Butoxycarbonylamino-2-methyl-3-phenyl-propionylamino)-3-phenyl-propionylamino]-octanoic acid
Show/Hide
|
C32H45N3O6
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0451190
|
8-[2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-2-methyl-3-phenyl-propionylamino]-octanoic acid
Show/Hide
|
C32H45N3O6
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0462968
|
(3-(4-fluorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C21H21FN4O2
|
2
|
| 1 |
IC50 = 240 nM
|
|
|
| 2 |
Ki = 530 nM
|
|
|
|
CP0459644
|
3,7-dihydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C25H22N2O3
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0548041
|
(R)-(4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
Show/Hide
|
C22H18FN5O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0511369
|
(5-(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C23H24ClN3O2
|
2
|
| 1 |
IC50 = 280 nM
|
|
|
| 2 |
Ki = 350 nM
|
|
|
|
CP0470545
|
[(1R)-2-methyl-1-phenylpropyl] N-[(2R)-1-(8-hydroxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C29H42N2O4
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0462971
|
(4-(5-chloro-2-methoxyphenyl)piperazin-1-yl)(3-(4-chlorophenyl)-1H-pyrazol-5-yl)methanone
Show/Hide
|
C21H20Cl2N4O2
|
2
|
| 1 |
IC50 = 370 nM
|
|
|
| 2 |
Ki = 400 nM
|
|
|
|
CP0425993
|
(4-(2-methoxyphenyl)piperazin-1-yl)(3-p-tolyl-1H-pyrazol-5-yl)methanone
Show/Hide
|
C22H24N4O2
|
2
|
| 1 |
IC50 = 390 nM
|
|
|
| 2 |
Ki = 510 nM
|
|
|
|
CP0459453
|
3-hydroxy-2-(4-hydroxyphenyl)-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C25H22N2O3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0088850
|
(4-fluorophenyl)-[3-[6-(trifluoromethyl)pyridin-2-yl]-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C18H13F4N5O
|
2
|
| 1 |
IC50 = 398.11 nM
|
|
|
| 2 |
Ki = 398.11 nM
|
|
|
|
CP0505046
|
tert-butyl N-[(2S)-1-[[1-[(4-hydroxyphenyl)methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C31H37N3O5
|
1
|
| 1 |
IC50 = 425 nM
|
|
|
|
CP0383289
|
tert-butyl N-[(2S)-1-[[1-[(4-hydroxyphenyl)methylamino]-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C31H37N3O5
|
1
|
| 1 |
IC50 = 425 nM
|
|
|
|
CP0554685
|
methyl N-[(8-bromo-3-methoxy-2-phenylquinoline-4-carbonyl)amino]-N-phenylcarbamate
Show/Hide
|
C25H20BrN3O4
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0534925
|
tert-butyl N-[(2S)-1-[[2-methyl-1-(nonylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C33H49N3O4
|
1
|
| 1 |
IC50 = 439 nM
|
|
|
|
CP0219171
|
(4-(2-methoxyphenyl)piperazin-1-yl)(3-phenyl-1H-pyrazol-5-yl)methanone
Show/Hide
|
C21H22N4O2
|
2
|
| 1 |
IC50 = 480 nM
|
|
|
| 2 |
Ki = 1100 nM
|
|
|
|
CP0462967
|
2-(4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C21H18ClN5O
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0171059
|
(4-fluorophenyl)-[3-(6-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C18H16FN5O
|
2
|
| 1 |
IC50 = 501.19 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0410505
|
[(8S)-8-methyl-3-(2-methyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C21H19N5OS2
|
2
|
| 1 |
IC50 = 501.19 nM
|
|
|
| 2 |
Ki = 316.23 nM
|
|
|
|
CP0460382
|
(3-(3-fluorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
|
C21H21FN4O2
|
2
|
| 1 |
IC50 = 580 nM
|
|
|
| 2 |
Ki = 1600 nM
|
|
|
|
CP0499740
|
(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C21H17N5OS
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0220343
|
[8,8-dimethyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-fluorophenyl)methanone
Show/Hide
|
C17H17FN6OS
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0429601
|
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-one
Show/Hide
|
C23H20N4O5
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0519389
|
(4-fluorophenyl)-[(8R)-8-methyl-3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C18H16FN5O
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
Ki = 794.33 nM
|
|
|
|
CP0574224
|
3-hydroxy-2-(4-methoxyphenyl)-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
IC50 = 965 nM
|
|
|
|
CP0461856
|
tert-butyl N-[(2S)-1-[[1-(benzylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
|
C31H37N3O4
|
1
|
| 1 |
IC50 = 1080 nM
|
|
|
|
CP0505421
|
(5-(4-chlorophenyl)isoxazol-3-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
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C21H20ClN3O3
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2
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| 1 |
IC50 = 1100 nM
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| 2 |
Ki = 1800 nM
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CP0369666
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(2-methyl-1-phenylpropyl) N-[(2R)-3-(1H-indol-2-yl)-2-methyl-1-oxo-1-(1-phenylethylamino)propan-2-yl]carbamate
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C31H35N3O3
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1
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| 1 |
IC50 = 1200 nM
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CP0511717
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(2-methyl-1-phenylpropyl) N-[(2R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-1-[[(1S)-1-phenylethyl]amino]propan-2-yl]carbamate
Show/Hide
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C31H35N3O3
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1
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| 1 |
IC50 = 1200 nM
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CP0462972
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(3-(2-fluorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
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C21H21FN4O2
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2
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| 1 |
IC50 = 1200 nM
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| 2 |
Ki = 2500 nM
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CP0064950
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(4-fluorophenyl)-[(8R)-8-methyl-3-(1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
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C15H13FN6OS
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1
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| 1 |
IC50 = 1258.93 nM
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CP0460381
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-hydroxyphenyl)piperazin-1-yl)methanone
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C20H19ClN4O2
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1
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| 1 |
IC50 = 1300 nM
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CP0537477
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[(1S)-2-methyl-1-phenylpropyl] N-[(2S)-1-[7-(carbamoylamino)heptylamino]-3-(2,3-difluorophenyl)-2-methyl-1-oxopropan-2-yl]carbamate
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C29H40F2N4O4
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1
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| 1 |
IC50 = 1400 nM
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CP0468165
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US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C22H19N3O5S
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1
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| 1 |
IC50 = 1400 nM
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CP0438344
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tert-butyl N-[(2R)-1-[[(2S)-1-amino-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 = 1490 nM
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CP0290288
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tert-butyl N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C23H29N3O4
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3
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| 1 |
IC50 = 1500 nM
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| 2 |
IC50 = 1550 nM
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| 3 |
IC50 = 1600 nM
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CP0538270
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tert-butyl N-[(2S)-1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 = 1520 nM
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CP0531553
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tert-butyl N-[(2S)-1-[(1-amino-2-methyl-1-oxo-3-phenylpropan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 = 1520 nM
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CP0403186
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3-hydroxy-2-(2-methoxyphenyl)-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
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C26H24N2O3
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1
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| 1 |
IC50 = 1527 nM
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CP0380682
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[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
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C20H16ClN7O
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2
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| 1 |
IC50 = 1584.89 nM
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| 2 |
Ki = 1584.89 nM
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CP0463189
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[4-(4-fluorophenyl)phenyl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
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C23H18FN5O
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2
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| 1 |
IC50 = 1584.89 nM
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| 2 |
Ki = 1995.26 nM
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CP0499739
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(4-phenylphenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
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C23H19N5O
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2
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| 1 |
IC50 = 1584.89 nM
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| 2 |
Ki = 1258.93 nM
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CP0500822
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tert-butyl N-[(2S)-1-[[(2S)-1-(8-hydroxyoctylamino)-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C32H47N3O5
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1
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| 1 |
IC50 = 1690 nM
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CP0541988
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tert-butyl N-[(2S)-1-[[(2S)-1-(8-hydroxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C32H47N3O5
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1
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| 1 |
IC50 = 1690 nM
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CP0879600
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4-Methyl-pentanoic acid [1-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethyl]-amide
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C28H33N5O3
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1
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| 1 |
IC50 = 1760 nM
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CP0511409
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(pyridin-4-ylmethyl)piperazin-1-yl)methanone
Show/Hide
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C20H20ClN5O
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1
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| 1 |
IC50 = 1800 nM
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CP0470613
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tert-butyl N-[(2S)-1-[[(2S)-1-amino-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 = 1830 nM
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CP0464712
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(3-cyclohexyl-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
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C21H28N4O2
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2
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| 1 |
IC50 = 2000 nM
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| 2 |
Ki = 2900 nM
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CP0117145
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tert-butyl N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate
Show/Hide
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C25H30N4O4
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1
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| 1 |
IC50 = 2080 nM
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CP0425992
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(3-phenyl-1H-pyrazol-5-yl)(4-phenylpiperazin-1-yl)methanone
Show/Hide
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C20H20N4O
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1
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| 1 |
IC50 = 2100 nM
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CP0462974
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(4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(methylsulfonyl)phenyl)-1H-pyrazol-5-yl)methanone
Show/Hide
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C22H24N4O4S
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1
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| 1 |
IC50 = 2500 nM
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CP0514457
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(4-fluorophenyl)-[3-(5-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
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C18H16FN5O
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2
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| 1 |
IC50 = 2511.89 nM
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| 2 |
Ki = 1584.89 nM
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CP0463022
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(R)-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)-2-methylpiperazin-1-yl)methanone
Show/Hide
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C22H23ClN4O2
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1
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| 1 |
IC50 = 2900 nM
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CP0461826
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1,6-Dibenzyl-indan-1-carboxylic acid phenethyl-amide
Show/Hide
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C32H31NO
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1
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| 1 |
IC50 = 3000 nM
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CP0460383
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4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl)-1-(2-methoxyphenyl)piperazin-2-one
Show/Hide
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C21H19ClN4O3
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1
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| 1 |
IC50 = 3100 nM
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CP0498786
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(4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-2-yl)-1H-pyrazol-5-yl)methanone
Show/Hide
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C20H21N5O2
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2
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| 1 |
IC50 = 3100 nM
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| 2 |
Ki = 3600 nM
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CP0920266
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4-Methyl-pentanoic acid {1-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-amide
Show/Hide
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C26H32N4O3
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1
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| 1 |
IC50 = 3270 nM
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CP0513239
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(3-benzyl-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
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C22H24N4O2
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1
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| 1 |
IC50 = 3300 nM
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CP0462969
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(pyridin-3-ylmethyl)piperazin-1-yl)methanone
Show/Hide
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C20H20ClN5O
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1
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| 1 |
IC50 = 3810 nM
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CP0546613
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[4-(4-chlorophenyl)phenyl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
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C23H18ClN5O
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2
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| 1 |
IC50 = 3981.07 nM
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| 2 |
Ki = 5011.87 nM
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CP0552570
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(4-fluorophenyl)-(4-methyl-1-quinolin-2-yl-6,7-dihydro-4H-triazolo[4,5-c]pyridin-5-yl)methanone
Show/Hide
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C22H18FN5O
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1
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| 1 |
IC50 = 4100 nM
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CP0401795
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tert-butyl N-[(2S)-1-[[1-(8-hydroxyoctylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C31H45N3O5
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1
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| 1 |
IC50 = 4310 nM
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CP0478801
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(pyridin-2-ylmethyl)piperazin-1-yl)methanone
Show/Hide
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C20H20ClN5O
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1
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| 1 |
IC50 = 5090 nM
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CP0448503
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1,6-Dibenzyl-indan-1-carboxylic acid (2,2-dimethyl-propyl)-amide
Show/Hide
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C29H33NO
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1
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| 1 |
IC50 = 5200 nM
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CP0503118
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(S)-N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-hydroxy-phenyl)-acetylamino]-2-methyl-3-phenyl-propionamide
Show/Hide
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C27H29N3O4
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1
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| 1 |
IC50 = 5890 nM
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CP0402734
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2-{(R)-2-[2-(4-Hydroxy-phenyl)-acetylamino]-3-phenyl-propionylamino}-2-methyl-3-phenyl-propionamide
Show/Hide
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C27H29N3O4
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1
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| 1 |
IC50 = 5890 nM
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CP0415196
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(3-fluorophenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
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C17H14FN5O
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2
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| 1 |
IC50 = 6309.57 nM
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| 2 |
Ki = 5011.87 nM
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CP0499294
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(4-fluorophenyl)-[3-(4-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
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C18H16FN5O
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2
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| 1 |
IC50 = 6309.57 nM
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| 2 |
Ki = 6309.57 nM
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CP0442094
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(4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-3-yl)-1H-pyrazol-5-yl)methanone
Show/Hide
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C20H21N5O2
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1
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| 1 |
IC50 = 7100 nM
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CP0505420
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(4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-4-yl)-1H-pyrazol-5-yl)methanone
Show/Hide
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C20H21N5O2
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1
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| 1 |
IC50 = 7200 nM
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CP0511368
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1-(2-methoxyphenyl)-4-(3-phenyl-1H-pyrazol-5-ylsulfonyl)piperazine
Show/Hide
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C20H22N4O3S
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1
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| 1 |
IC50 = 7400 nM
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CP0499741
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(4-fluorophenyl)-[(8S)-8-methyl-3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
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C18H16FN5O
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2
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| 1 |
IC50 = 7943.28 nM
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| 2 |
Ki = 7943.28 nM
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CP0405330
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1,6-Dibenzyl-indan-1-carboxylic acid methyl ester
Show/Hide
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C25H24O2
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1
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| 1 |
IC50 = 8000 nM
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CP0574642
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(4-fluorophenyl)-(7-methyl-3-quinolin-2-yl-5,7-dihydro-4H-[1,2]oxazolo[5,4-c]pyridin-6-yl)methanone
Show/Hide
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C23H18FN3O2
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1
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| 1 |
IC50 = 8200 nM
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CP0535482
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tert-butyl N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C23H29N3O5
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1
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| 1 |
IC50 = 8620 nM
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CP0424420
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propan-2-yl N-[(2S)-3-(1H-indol-3-yl)-1-[2-(1H-indol-3-yl)ethylamino]-1-oxopropan-2-yl]carbamate
Show/Hide
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C25H28N4O3
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1
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| 1 |
IC50 = 9420 nM
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CP0429270
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tert-butyl N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C25H30N4O4
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1
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| 1 |
IC50 = 9610 nM
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CP0457378
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tert-butyl N-[(2R)-1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 = 10000 nM
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CP0505249
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[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-2-methyl-1-oxo-3-phenyl-1-[[(1S)-1-phenylethyl]amino]propan-2-yl]carbamate
Show/Hide
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C29H34N2O3
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1
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| 1 |
IC50 > 10000 nM
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CP0407327
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tert-butyl N-[1-[[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0448497
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tert-butyl N-[1-[[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-N-methylcarbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0455368
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tert-butyl N-[(2R)-1-[(1-amino-2-methyl-1-oxo-3-phenylpropan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0493966
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tert-butyl N-[(2S)-1-[(1-amino-1-oxo-3-phenylpropan-2-yl)-methylamino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0511221
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tert-butyl N-[1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-N-methylcarbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0542465
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tert-butyl N-[1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-2-methyl-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0555220
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tert-butyl N-[(2R)-1-[(1-amino-1-oxo-3-phenylpropan-2-yl)-methylamino]-1-oxo-3-phenylpropan-2-yl]carbamate
Show/Hide
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C24H31N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0307130
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3-{[(3-Benzyl-2-aza-bicyclo[2.2.1]heptane-2-carbonyl)-amino]-methyl}-indole-1-carboxylic acid benzyl ester
Show/Hide
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C31H31N3O3
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1
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| 1 |
IC50 = 10000 nM
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CP0795225
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1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
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C19H16N2O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0426045
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(3-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
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C21H21ClN4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0426047
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(4-(biphenyl-2-yl)piperazin-1-yl)(3-phenyl-1H-pyrazol-5-yl)methanone
Show/Hide
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C26H24N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0462966
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(cyclohexylmethyl)piperazin-1-yl)methanone
Show/Hide
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C21H27ClN4O
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1
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| 1 |
IC50 > 10000 nM
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CP0463021
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(4-methoxyphenyl)piperazin-1-yl)methanone
Show/Hide
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C21H21ClN4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0464710
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2-(4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl)piperazin-1-yl)benzamide
Show/Hide
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C21H20ClN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0511370
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-o-tolylpiperazin-1-yl)methanone
Show/Hide
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C21H21ClN4O
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1
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| 1 |
IC50 > 10000 nM
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CP0511410
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(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
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C21H18ClF3N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0441461
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[4-(5-methylfuran-2-yl)phenyl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
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C22H19N5O2
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 15848.93 nM
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CP0845709
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-3-methyl-butyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C37H57N7O11S
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1
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| 1 |
IC50 > 10000 nM
|
|
|
|
CP0848424
|
(S)-N-((S)-1-{[(R)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
|
C40H55N7O11S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0852309
|
(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-carboxy-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
|
C35H51N7O13S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401896
|
4-phenyl-2-[(1S)-1-phenylpropyl]-[1,2]thiazolo[5,4-c]quinolin-1-one
Show/Hide
|
C25H20N2OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0455939
|
2-phenyl-3-[[2-phenyl-4-[[(1S)-1-phenylpropyl]carbamoyl]quinolin-3-yl]disulfanyl]-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C50H42N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0528146
|
(4-fluorophenyl)-(7-methyl-3-quinolin-2-yl-5,7-dihydro-4H-[1,2]oxazolo[3,4-c]pyridin-6-yl)methanone
Show/Hide
|
C23H18FN3O2
|
2
|
| 1 |
IC50 = 10300 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0438061
|
(4-fluorophenyl)-[(7R)-7-methyl-3-quinolin-2-yl-5,7-dihydro-4H-[1,2]oxazolo[3,4-c]pyridin-6-yl]methanone
Show/Hide
|
C23H18FN3O2
|
1
|
| 1 |
IC50 = 11800 nM
|
|
|
|
CP0551073
|
(4-fluorophenyl)-[(7S)-7-methyl-3-quinolin-2-yl-5,7-dihydro-4H-[1,2]oxazolo[3,4-c]pyridin-6-yl]methanone
Show/Hide
|
C23H18FN3O2
|
1
|
| 1 |
IC50 = 13700 nM
|
|
|
|
CP0120399
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(5-methyl-1,3,4-thiadiazol-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C16H15FN6OS
|
1
|
| 1 |
IC50 = 15848.93 nM
|
|
|
|
CP0544449
|
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydropyrimidin-2(1H)-one
Show/Hide
|
C24H21N3O5
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0413974
|
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
Show/Hide
|
C22H19N3O5S
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0380677
|
(4-methoxyphenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C18H17N5O2
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0380679
|
(3-methoxyphenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C18H17N5O2
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0380680
|
(2-fluorophenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C17H14FN5O
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0415195
|
(2-methoxyphenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C18H17N5O2
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0463196
|
(4-benzylphenyl)-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C24H21N5O
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0514662
|
(4-fluorophenyl)-[3-(3-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C18H16FN5O
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0547404
|
[4-(4-methoxyphenyl)phenyl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
Show/Hide
|
C24H21N5O2
|
2
|
| 1 |
IC50 > 31622.78 nM
|
|
|
| 2 |
Ki > 31622.78 nM
|
|
|
|
CP0468280
|
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-one
Show/Hide
|
C23H20N4O5
|
1
|
| 1 |
IC50 = 55000 nM
|
|
|
|
CP0478024
|
(4-(2-methoxyphenyl)piperazin-1-yl)(3-phenylisoxazol-5-yl)methanone
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0403323
|
N-[(2Z,3R)-5-[4-[3-[(2R)-1-amino-3-hydroxy-1-oxopropan-2-yl]-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C32H40Cl4N6O5
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0406322
|
3,5-Dichloro-N-[(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-((R)-3-methylcarbamoylmethyl-2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C33H41Cl4N5O4
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0409122
|
N-[(2Z,3R)-5-[4-[3-(1-amino-2-methyl-1-oxopropan-2-yl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C33H42Cl4N6O4
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0326360
|
(2S)-N-[(4-chlorophenyl)methyl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide
Show/Hide
|
C31H31Cl3FN3O3
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0394239
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(2-methanesulfonylamino-ethyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C32H42Cl4N6O5S
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0467123
|
N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C31H38Cl4N6O4
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0406314
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(2-hydroxy-2-methyl-propyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C33H43Cl4N5O4
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0461033
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-yl-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C34H38Cl4N6O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0464095
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-morpholin-4-yl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C33H42Cl4N6O4
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0536011
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(N-hydroxycarbamimidoylmethyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C31H39Cl4N7O4
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0247643
|
4-[4-[acetyl(propyl)amino]piperidin-1-yl]-2-(3,4-dichlorophenyl)-N-[(1R)-1-(4-fluorophenyl)-2-hydroxyethyl]-2-methylbutanamide
Show/Hide
|
C29H38Cl2FN3O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0412079
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-isopropyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C32H41Cl4N5O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0404000
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-hydroxy-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C29H35Cl4N5O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0464148
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-methyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C30H37Cl4N5O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0506846
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-ylmethyl-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C35H40Cl4N6O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0440468
|
3-Amino-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C25H23N3O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0424454
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-methylcarbamoylmethyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C32H40Cl4N6O4
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0460321
|
3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C25H22N2O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0509985
|
3-(2-Hydroxy-ethoxy)-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C27H26N2O3
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0378844
|
3-methoxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0916168
|
3-amino-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C25H23N3O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0377632
|
ethyl 2-[2-phenyl-4-[[(1S)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetate
Show/Hide
|
C29H28N2O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0380707
|
3,5-Dichloro-N-((R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-{4-[2-oxo-3-(2H-tetrazol-5-ylmethyl)-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-pentyl)-N-methyl-benzamide
Show/Hide
|
C31H37Cl4N9O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0373762
|
3-Dimethylaminomethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C28H29N3O
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0431498
|
2-[2-phenyl-4-[[(1R)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetic acid
Show/Hide
|
C27H24N2O4
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0372925
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-furan-3-ylmethyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C34H39Cl4N5O4
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0383939
|
3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C25H22N2O2
|
2
|
| 1 |
Ki = 2.4 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0430274
|
3-Dimethylcarbamoylmethoxy-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C29H29N3O3
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0400721
|
(2R)-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-[(2R)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-2-methylbutanamide
Show/Hide
|
C35H39Cl2FN4O5
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0922660
|
3-amino-N-(cyclopropyl(3-fluorophenyl)methyl)-2-phenylquinoline-4-carboxamide
Show/Hide
|
C26H22FN3O
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0393865
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-thiophen-3-ylmethyl-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C34H39Cl4N5O3S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0944082
|
3-amino-2-(3-fluorophenyl)-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C25H22FN3O
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0465157
|
3-(2-aminoethoxy)-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C27H27N3O2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0851116
|
3-amino-N-(cyclopropyl(phenyl)methyl)-2-phenylquinoline-4-carboxamide
Show/Hide
|
C26H23N3O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0944083
|
3-amino-N-(cyclopropyl(2-fluorophenyl)methyl)-2-phenylquinoline-4-carboxamide
Show/Hide
|
C26H22FN3O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0462356
|
3-Ethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C27H26N2O
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0522388
|
3-[2-(dimethylamino)ethoxy]-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C29H31N3O2
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0392058
|
3-Methoxy-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C26H24N2O2
|
2
|
| 1 |
Ki = 5.8 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0502689
|
3-(2-amino-2-oxoethoxy)-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C27H25N3O3
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0431085
|
3-Ethyl-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C27H26N2O
|
2
|
| 1 |
Ki = 6.31 nM
|
|
|
| 2 |
Ki = 7.1 nM
|
|
|
|
CP0919294
|
3-amino-N-(cyclopropyl(3-fluorophenyl)methyl)-2-(3-fluorophenyl)quinoline-4-carboxamide
Show/Hide
|
C26H21F2N3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0498277
|
2-phenyl-N-[(1S)-1-phenylpropyl]-3-(2-pyrrolidin-1-ylethoxy)quinoline-4-carboxamide
Show/Hide
|
C31H33N3O2
|
1
|
| 1 |
Ki = 6.8 nM
|
|
|
|
CP0943049
|
3-amino-2-(4-fluorophenyl)-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
|
C25H22FN3O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0504883
|
(2R)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N,2-dimethylbutanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C38H43Cl2F4N5O6
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0384156
|
3-[3-(dimethylamino)propoxy]-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0430289
|
3-Methyl-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C26H24N2O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0440758
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C32H33Cl4N5O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0916167
|
3-amino-N-(cyclopropyl(phenyl)methyl)-2-(3-fluorophenyl)quinoline-4-carboxamide
Show/Hide
|
C26H22FN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0377630
|
3-[[2-(dimethylamino)acetyl]amino]-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C29H30N4O2
|
1
|
| 1 |
Ki = 10.7 nM
|
|
|
|
CP0463980
|
(R)-2-[3-(1-{(R)-5-[(3,5-Dichloro-benzoyl)-methyl-amino]-3-(3,4-dichloro-phenyl)-4-[(Z)-methoxyimino]-pentyl}-piperidin-4-yl)-2-oxo-tetrahydro-pyrimidin-1-yl]-3-(4-hydroxy-phenyl)-propionic acid ethyl ester
Show/Hide
|
C40H47Cl4N5O6
|
1
|
| 1 |
Ki = 10.9 nM
|
|
|
|
CP0405287
|
2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetic acid
Show/Hide
|
C34H35Cl4N5O5
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0439307
|
benzyl 2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxo-1,3-diazinan-1-yl]acetate
Show/Hide
|
C38H43Cl4N5O5
|
1
|
| 1 |
Ki = 11.8 nM
|
|
|
|
CP0495635
|
2-Phenyl-3-propyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C28H28N2O
|
2
|
| 1 |
Ki = 12.59 nM
|
|
|
| 2 |
Ki = 13.7 nM
|
|
|
|
CP0041194
|
(R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester
Show/Hide
|
C25H20N2O3
|
2
|
| 1 |
Ki = 13 nM
|
|
|
| 2 |
Ki = 925 nM
|
|
|
|
CP0325308
|
(S)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester
Show/Hide
|
C25H20N2O3
|
2
|
| 1 |
Ki = 13.3 nM
|
|
|
| 2 |
Ki = 926 nM
|
|
|
|
CP0497384
|
3-Butyl-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C29H30N2O
|
2
|
| 1 |
Ki = 15.2 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0522603
|
3-acetamido-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C27H25N3O2
|
1
|
| 1 |
Ki = 15.9 nM
|
|
|
|
CP0394110
|
2-Phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide
Show/Hide
|
C25H22N2O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0471126
|
(2R)-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methyl-N-[(2R)-1-[2-(methylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]butanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C38H43Cl2F4N5O6
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0424545
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-methyl-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C33H35Cl4N5O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0439823
|
2-Phenyl-quinoline-4-carboxylic acid (2-oxo-1-phenyl-propyl)-amide
Show/Hide
|
C25H20N2O2
|
2
|
| 1 |
Ki = 25.12 nM
|
|
|
| 2 |
Ki = 27.4 nM
|
|
|
|
CP0410028
|
(2R)-N-[(2R)-1-(3-aminopropylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N,2-dimethylbutanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C39H45Cl2F4N5O6
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0415009
|
methyl 2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetate
Show/Hide
|
C35H37Cl4N5O5
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0439820
|
3-Chloro-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C25H21ClN2O
|
1
|
| 1 |
Ki = 29.9 nM
|
|
|
|
CP0430593
|
3-Fluoro-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
|
C25H21FN2O
|
1
|
| 1 |
Ki = 30.3 nM
|
|
|
|
CP0383278
|
methyl 2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
Show/Hide
|
C25H20N2O3
|
3
|
| 1 |
Ki = 30.7 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
| 3 |
Ki = 31.62 nM
|
|
|
|
CP0376712
|
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C25H22N2O
|
2
|
| 1 |
Ki = 31.62 nM
|
|
|
| 2 |
Ki = 34 nM
|
|
|
|
CP0410027
|
(2R)-2-(3,4-dichlorophenyl)-N-[(2R)-1-[2-(dimethylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide
Show/Hide
|
C37H44Cl2FN5O4
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0462720
|
3-bromo-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
|
C25H21BrN2O
|
1
|
| 1 |
Ki = 37.2 nM
|
|
|
|
CP0400719
|
(2R)-N-[(1S)-2-(2-aminoethylamino)-2-oxo-1-phenylethyl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride
Show/Hide
|
C34H39Cl3FN5O4
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0491963
|
2,3-Diphenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C31H26N2O
|
2
|
| 1 |
Ki = 45.3 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0395228
|
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-butyl)-amide
Show/Hide
|
C26H24N2O
|
2
|
| 1 |
Ki = 47.2 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0400825
|
3-Hexyl-2-phenyl-quinoline-4-carboxylic acid (1-phenyl-propyl)-amide
Show/Hide
|
C31H34N2O
|
2
|
| 1 |
Ki = 50.12 nM
|
|
|
| 2 |
Ki = 55.4 nM
|
|
|
|
CP0452816
|
(2R)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride
Show/Hide
|
C35H41Cl3FN5O4
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0410025
|
(2R)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride
Show/Hide
|
C35H41Cl3FN5O4
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0431143
|
2-Phenyl-quinoline-4-carboxylic acid (2-methyl-1-phenyl-propyl)-amide
Show/Hide
|
C26H24N2O
|
2
|
| 1 |
Ki = 74.3 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0441552
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-ethyl-benzamide
Show/Hide
|
C33H35Cl4N5O3
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0439286
|
3,5-Dichloro-N-cyclopropyl-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-benzamide
Show/Hide
|
C34H35Cl4N5O3
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0536764
|
(2R)-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-[(2R)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-2-methylpentanamide
Show/Hide
|
C36H41Cl2FN4O5
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0376331
|
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-cyclopentyl)-amide
Show/Hide
|
C27H24N2O
|
1
|
| 1 |
Ki = 129 nM
|
|
|
|
CP0506613
|
2-Phenyl-quinoline-4-carboxylic acid benzhydryl-amide
Show/Hide
|
C29H22N2O
|
1
|
| 1 |
Ki = 134 nM
|
|
|
|
CP0501405
|
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-pentyl)-amide
Show/Hide
|
C27H26N2O
|
2
|
| 1 |
Ki = 146 nM
|
|
|
| 2 |
Ki = 158.49 nM
|
|
|
|
CP0535142
|
3-phenyl-N-(1-phenylpentyl)naphthalene-1-carboxamide
Show/Hide
|
C28H27NO
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0404588
|
N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxobenzimidazol-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-ethylbenzamide
Show/Hide
|
C35H38Cl4N6O4
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0410762
|
2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-ethylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetic acid
Show/Hide
|
C35H37Cl4N5O5
|
1
|
| 1 |
Ki = 176 nM
|
|
|
|
CP0478900
|
2-Phenyl-quinoline-4-carboxylic acid (2-hydroxy-1-phenyl-ethyl)-amide
Show/Hide
|
C24H20N2O2
|
2
|
| 1 |
Ki = 199.53 nM
|
|
|
| 2 |
Ki = 207 nM
|
|
|
|
CP0466601
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-(2-fluoro-ethyl)-benzamide
Show/Hide
|
C33H34Cl4FN5O3
|
1
|
| 1 |
Ki = 231 nM
|
|
|
|
CP0409129
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-ethylcarbamoylmethyl-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
|
C37H42Cl4N6O4
|
1
|
| 1 |
Ki = 281 nM
|
|
|
|
CP0393095
|
2-Phenyl-quinoline-4-carboxylic acid (1-methyl-1-phenyl-ethyl)-amide
Show/Hide
|
C25H22N2O
|
1
|
| 1 |
Ki = 295 nM
|
|
|
|
CP0393934
|
2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-(2-fluoroethyl)amino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetic acid
Show/Hide
|
C35H36Cl4FN5O5
|
1
|
| 1 |
Ki = 304 nM
|
|
|
|
CP0439288
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-ylmethyl-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-ethyl-benzamide
Show/Hide
|
C39H40Cl4N6O3
|
1
|
| 1 |
Ki = 312 nM
|
|
|
|
CP0393069
|
2-Phenyl-quinoline-4-carboxylic acid (2-methoxy-1-phenyl-ethyl)-amide
Show/Hide
|
C25H22N2O2
|
1
|
| 1 |
Ki = 314 nM
|
|
|
|
CP0395229
|
2-Phenyl-quinoline-4-carboxylic acid (3-hydroxy-1-phenyl-propyl)-amide
Show/Hide
|
C25H22N2O2
|
2
|
| 1 |
Ki = 382 nM
|
|
|
| 2 |
Ki = 398.11 nM
|
|
|
|
CP0395227
|
2-Phenyl-quinoline-4-carboxylic acid (methylcarbamoyl-phenyl-methyl)-amide
Show/Hide
|
C25H21N3O2
|
2
|
| 1 |
Ki = 426 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0398174
|
2-Phenyl-quinoline-4-carboxylic acid (2,2,2-trifluoro-1-phenyl-ethyl)-amide
Show/Hide
|
C24H17F3N2O
|
2
|
| 1 |
Ki = 454 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0386204
|
2-Phenyl-quinoline-4-carboxylic acid (dimethylcarbamoyl-phenyl-methyl)-amide
Show/Hide
|
C26H23N3O2
|
2
|
| 1 |
Ki = 488 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0394390
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(2-methoxy-ethyl)-2-oxo-2,3-dihydro-benzoimidazol-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
|
C36H41Cl4N5O4
|
1
|
| 1 |
Ki = 572 nM
|
|
|
|
CP0496842
|
N-[3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]acetamide
Show/Hide
|
C23H23F6NO2
|
1
|
| 1 |
Ki = 631 nM
|
|
|
|
CP0404001
|
3,5-Dichloro-N-{(R)-5-[4-(3-cyanomethyl-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
|
C35H36Cl4N6O3
|
1
|
| 1 |
Ki = 674 nM
|
|
|
|
CP0452818
|
(2R)-N-[(1S)-2-(2-aminoethylamino)-2-oxo-1-phenylethyl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C37H41Cl2F4N5O6
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0409130
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{3-[(2-methoxy-ethylcarbamoyl)-methyl]-2-oxo-2,3-dihydro-benzoimidazol-1-yl}-piperidin-1-yl)-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
|
C38H44Cl4N6O5
|
1
|
| 1 |
Ki = 945 nM
|
|
|
|
CP0388016
|
3-Phenyl-3-[(2-phenyl-quinoline-4-carbonyl)-amino]-propionic acid methyl ester
Show/Hide
|
C26H22N2O3
|
2
|
| 1 |
Ki = 973 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0485947
|
2-Phenyl-quinoline-4-carboxylic acid (carbamoyl-phenyl-methyl)-amide
Show/Hide
|
C24H19N3O2
|
2
|
| 1 |
Ki = 983 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0410965
|
(2R)-2-(3,4-dichlorophenyl)-N-[(2R)-1-[2-(dimethylamino)ethylamino]-1-oxo-3-phenylpropan-2-yl]-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide
Show/Hide
|
C38H46Cl2FN5O4
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0529758
|
2-Phenyl-quinoline-4-carboxylic acid ((S)-2-dimethylamino-1-phenyl-ethyl)-amide
Show/Hide
|
C26H25N3O
|
1
|
| 1 |
Ki = 1068 nM
|
|
|
|
CP0509917
|
2-Phenyl-quinoline-4-carboxylic acid ((S)-2-amino-1-phenyl-ethyl)-amide
Show/Hide
|
C24H21N3O
|
1
|
| 1 |
Ki = 1144 nM
|
|
|
|
CP0504317
|
1-((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-2-oxo-5-phenylpyrrolidin-3-yl)pyrrolidin-2-one
Show/Hide
|
C25H24F6N2O3
|
1
|
| 1 |
Ki = 1254 nM
|
|
|
|
CP0389408
|
(2S)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide;hydrochloride
Show/Hide
|
C35H41Cl3FN5O4
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0410024
|
(2R)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide;hydrochloride
Show/Hide
|
C35H41Cl3FN5O4
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0452817
|
(2R)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylpentanamide;2,2,2-trifluoroacetic acid
Show/Hide
|
C38H43Cl2F4N5O6
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0415271
|
(S)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid
Show/Hide
|
C24H18N2O3
|
1
|
| 1 |
Ki = 1653 nM
|
|
|
|
CP0448859
|
(2S)-N-[(2R)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride
Show/Hide
|
C35H41Cl3FN5O4
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0442833
|
1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-methyl-3-phenylcyclobutane-1-carboxamide
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
Ki = 1999 nM
|
|
|
|
CP0376363
|
N-[3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]acetamide
Show/Hide
|
C23H23F6NO2
|
1
|
| 1 |
Ki = 2131 nM
|
|
|
|
CP0452815
|
(2R)-N-[(1S)-2-(2-aminoethylamino)-2-oxo-1-phenylethyl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylbutanamide;hydrochloride
Show/Hide
|
C34H39Cl3FN5O4
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0384155
|
2-Phenyl-quinoline-4-carboxylic acid (1,2-diphenyl-ethyl)-amide
Show/Hide
|
C30H24N2O
|
2
|
| 1 |
Ki = 3162.28 nM
|
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| 2 |
Ki = 3511 nM
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CP0486827
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(S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-5-phenylpyrrolidin-2-one
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C21H19F6NO2
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1
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| 1 |
Ki = 3815 nM
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CP0556203
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(2R)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylpentanamide;hydrochloride
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C36H43Cl3FN5O4
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1
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| 1 |
Ki = 3981.07 nM
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CP0498166
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(R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-phenylcyclobutanamine
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C21H21F6NO
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1
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| 1 |
Ki = 4051 nM
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CP0430598
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2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-octyl)-amide
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C30H32N2O
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2
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| 1 |
Ki = 4874 nM
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| 2 |
Ki = 5011.87 nM
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CP0410026
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(2S)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-5-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-N-methylpentanamide;hydrochloride
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C36H43Cl3FN5O4
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1
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| 1 |
Ki = 6309.57 nM
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CP0471128
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(2S)-N-[(2S)-1-(2-aminoethylamino)-1-oxo-3-phenylpropan-2-yl]-2-(3,4-dichlorophenyl)-4-(6-fluoro-1-methyl-2-oxospiro[3,1-benzoxazine-4,4'-piperidine]-1'-yl)-2-methylbutanamide;hydrochloride
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C35H41Cl3FN5O4
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1
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| 1 |
Ki = 10000 nM
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