Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[8,8-dimethyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-fluorophenyl)methanone
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 PubChem ID
CID: 122187069
Canonical SMILES
Cc1nsc(n1)-c1nnc2n1CCN(C(=O)c1ccc(F)cc1)C2(C)C
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Compound Formula C17H17FN6OS
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 630.96 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 199.53 nM