Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-(4-fluorophenyl)(8-methyl-3-(quinolin-2-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
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 PubChem ID
CID: 67452275
Canonical SMILES
C[C@H]1N(CCn2c1nnc2-c1ccc2ccccc2n1)C(=O)c1ccc(F)cc1
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Compound Formula C22H18FN5O
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS