Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4-fluorophenyl)-[(8R)-8-methyl-3-(1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
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 PubChem ID
CID: 122187068
Canonical SMILES
C[C@H]1N(CCn2c1nnc2-c1ncns1)C(=O)c1ccc(F)cc1
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Compound Formula C15H13FN6OS
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1258.93 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1258.93 nM