Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-ethyl)-amide
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 PubChem ID
CID: 2849628
SID: 14921001
Canonical SMILES
CC(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1
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Compound Formula C24H20N2O
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
IC50 = 33.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 2200 nM
   TI
   LI
   LO
   TS
3
Ki = 251.19 nM
   TI
   LI
   LO
   TS
4
Ki = 264 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 9900 nM
   TI
   LI
   LO
   TS