Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)-2-methylpiperazin-1-yl)methanone
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 PubChem ID
CID: 54579946
Canonical SMILES
COc1ccccc1N1CCN([C@@H](C)C1)C(=O)c1cc(n[nH]1)-c1ccc(Cl)cc1
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Compound Formula C22H23ClN4O2
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
2
Ki = 370 nM
   TI
   LI
   LO
   TS