Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[4-(4-chlorophenyl)phenyl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
    Show/Hide
 PubChem ID
CID: 118735345
Canonical SMILES
Clc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCn2c(C1)nnc2-c1ccccn1
    Show/Hide
Compound Formula C23H18ClN5O
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 3981.07 nM
   TI
   LI
   LO
   TS
2
Ki = 5011.87 nM
   TI
   LI
   LO
   TS