Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-(4-thiophen-2-ylphenyl)methanone
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 PubChem ID
CID: 53482149
SID: 126584852
Canonical SMILES
O=C(N1CCn2c(C1)nnc2-c1ccccn1)c1ccc(cc1)-c1cccs1
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Compound Formula C21H17N5OS
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 630.96 nM
   TI
   LI
   LO
   TS
2
Ki = 501.19 nM
   TI
   LI
   LO
   TS