General Information of the Compound
| Compound ID |
CP0000036
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| Compound Name |
(+-)-2-(p-isobutylphenyl)propionic acid
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| Synonyms |
Actiprofen
(RS)-Ibuprofen
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
2-[4-(2-methylpropyl)phenyl]propanoic acid
4-Isobutylhydratropic acid
ACHES-N-PAIN
Act-3
Act-3 (TN)
Adex 200
Adran
Advil
Advil (TN)
Ak+C2278tren
Aktre (TN)
Alaxan
Alaxan (TN)
Algofen
Algoflex (TN)
Alivium (TN)
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apsifen
Apsifen-F
Arthrofen (TN)
Artofen
Artril
Artril 300
Balkaprofen
Betaprofen
Bloom
Bluton
Bonifen (TN)
Brofen
Brufanic
Brufen
Brufen (TN)
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bugesic (TN)
Bukrefen
Bupron
Buracaps
Burana
Burana (TN)
Butylenin
Caldolor (TN)
Calprofen (TN)
Cap-Profen
Carol;Cesra
Citalgan
Cobo
Codral
Combiflam
Cunil
DOLO PUREN
Daiprophen
Dalsy
Dalsy (TN)
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dismenol (TN)
Diverin (TN)
Dolgirid
Dolgit
Dolgit (TN)
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-Spedifen (TN)
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dolofort (TN)
Dologel
Dolomax
Doloraz (TN)
Doloren
Dolormin
Dolormin (TN)
Doltibil
Dolven
Donjust B
Dorival
Dorival (TN)
Drin
Duafen
Duobrus
Dura-Ibu
Dysdolen
Easifon
Ebufac
Ebufac (TN)
Emflam
Emflam-200
EmuProfen (TN)
Epobron
Eputex
Ergix
Espidifen (TN)
Esprenit
Eve (TN)
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid (TN)
Fenbid;Fendol
Fenpaed (TN)
Fenspan
Fibraflex
Finalflex (TN)
Galprofen (TN)
Gelufene
Gofen
Grefen
Gynofug
Haltran
Hedex (TN)
Herron Blue (TN)
I 4883
I-profen (TN)
IB-100
IBU-Ratiopharm (TN)
IBUFEN (TN)
IBUPROPHEN
IP 82
IP-82
IP82
Ibalgin (TN)
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Tab
Ibu-Tab 200
Ibu-Vivimed (TN)
Ibu-slo
Ibu-slow
IbuHEXAL (TN)
Ibubest
Ibubeta
Ibucasen
Ibudol
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugel (TN)
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibuleve (TN)
Ibulgan
Ibum (TN)
Ibumax (TN)
Ibumed
Ibumerck
Ibumetin
Ibumetin (TN)
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprom (TN)
Ibuprophen
Ibuprosyn (TN)
Ibusal
Ibutid
Ibux (TN)
Ibuxin (TN)
Ifen
Inabrin
Inflam
Inoven
Ipren
Ipren (TN)
Irfen
Isodol
Jenaprofen
Junifen
Kesan
Kratalgin
Kratalgin (TN)
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
Malafene
Manypren
Medicol (TN)
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Moment (TN)
Motrin
Motrin (TN)
Motrin IB
Mynosedin
Nagifen-D
Napacetin
Narfen
Narfen (TN)
Neo-Helvagit
Neo-Mindol
Neobrufen
Neobrufen (TN)
Neofen (TN)
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Norvectan (TN)
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nuprin (TN)
Nureflex (TN)
Nurofen
Nurofen (TN)
Optifen
Opturem
Oralfene
Orbifen (TN)
Ostarin
Ostofen
Ozonol
Paduden
Panafen
Panafen (TN)
Pantrop
Paxofen
Pedia-Profen
PediaProfen
Perifar (TN)
Perofen
Proartinal
Profen
Profin (TN)
Proflex
Provon
Quadrax
RD 13621
Rafen
Ranofen
Ratiodolor (TN)
Rebugen
Relcofen
Retard (TN)
Rhinadvil
Rimafen (TN)
Rofen
Roidenin
Rufen
Rufin
Rupan
Sadefen
Salivia
Salprofen
Salvarina (TN)
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solpaflex (TN)
Solufen
Spedifen (TN)
Speedpain NANO (TN)
Spidifen (TN)
Stelar
Sugafen
Suprafen
Suspren
Syntofene
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Upfen (TN)
Uprofen
Urem
VUFB 9649
Zafen
Zofen
ibuprofen
p-Isobutylhydratropic acid
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| Structure |
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| Formula |
C13H18O2
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| Molecular Weight |
206.285
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| Canonical SMILES |
CC(C)Cc1ccc(cc1)C(C)C(O)=O
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| InChI |
InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
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| InChIKey |
HEFNNWSXXWATRW-UHFFFAOYSA-N
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| CAS |
58560-75-1
15687-27-1
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01743, Polyunsaturated fatty acid 5-lipoxygenase
Protein ID: PT01062, Prostaglandin G/H synthase 2
Protein ID: PT00901, Prostaglandin G/H synthase 2
Protein ID: PT04064, Solute carrier family 22 member 6
Clinical Information about the Compound