Brief Information of the Cell Line and Protein
Cell Line ID: CL000065 , HEK293-EBNA
Synonyms
293 c18
293c18
HEK 293 c18
HEK-293 c18
HEK293-EBNA1
HEK-293-EBNA
HEK 293-EBNA
HEK 293 EBNA
HEK293EBNA
293 EBNA
293-EBNA1
293-EBNA
293/EBNA
293EBNA
EBNA-293
EBNA293
293E
HEK293E
HEK/EBNA
HEK-EBNA
HEK.EBNA
293/EBNA-1
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6974
Protein ID: PT01588 , Corticotropin-releasing factor receptor 1
Gene Name CRHR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P34998
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000065  Protein ID: PT01588
 
Compound ID Compound Name Compound Formula
CP0392201
3-(2,4-dibromophenyl)-N-heptan-4-yl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H22Br2N6
 1
1
Ki = 0.8 nM
   TI
   LI
   LO
   TS
CP0283841
Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine
   Show/Hide
C24H34N4
 1
1
Ki = 0.84 nM
   TI
   LI
   LO
   TS
CP0412470
9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-2,8-dimethylpurin-6-amine
   Show/Hide
C22H30BrN5
 1
1
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0406407
9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-2-methyl-8-(trifluoromethyl)purin-6-amine
   Show/Hide
C22H27BrF3N5
 1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS
CP0497796
3-(2-Bromo-4-isopropyl-phenyl)-7-(1-ethyl-pentyloxy)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C21H28BrN5O
 1
1
Ki = 1.5 nM
   TI
   LI
   LO
   TS
CP0255382
Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-ethyl-amine
   Show/Hide
C23H32N4
 2
1
Ki = 1.61 nM
   TI
   LI
   LO
   TS
2
Ki = 2.7 nM
   TI
   LI
   LO
   TS
CP0495062
3-(2-Bromo-4-isopropyl-phenyl)-7-(1-ethyl-propoxy)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C19H24BrN5O
 1
1
Ki = 1.9 nM
   TI
   LI
   LO
   TS
CP0505801
3-(2-Bromo-4-isopropyl-phenyl)-7-(1-methoxymethyl-propoxy)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C19H24BrN5O2
 1
1
Ki = 1.9 nM
   TI
   LI
   LO
   TS
CP0523276
Butyl-ethyl-[3-(4-isopropyl-2-methylsulfanyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-b]pyridin-7-yl]-amine
   Show/Hide
C22H31N5S
 1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CP0505264
(2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-nitro-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C22H23BrN4O2
 1
1
Ki = 2.4 nM
   TI
   LI
   LO
   TS
CP0393666
(2-Bromo-4-methylsulfanyl-phenyl)-ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C21H19BrF3N3S
 1
1
Ki = 2.5 nM
   TI
   LI
   LO
   TS
CP0514436
3-(2-bromo-4-propan-2-ylphenyl)-N-hexan-3-yl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H27BrN6
 1
1
Ki = 2.8 nM
   TI
   LI
   LO
   TS
CP0534479
9-(2-Bromo-4-isopropyl-phenyl)-6-(1-ethyl-pentyloxy)-2-methyl-9H-purine
   Show/Hide
C22H29BrN4O
 1
1
Ki = 2.9 nM
   TI
   LI
   LO
   TS
CP0514429
3-(2-bromo-4,6-dimethoxyphenyl)-N-butyl-N-ethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6O2
 1
1
Ki = 3 nM
   TI
   LI
   LO
   TS
CP0498255
(2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C23H23BrF3N3
 1
1
Ki = 3.1 nM
   TI
   LI
   LO
   TS
CP0464912
3-(2-bromo-4-propan-2-ylphenyl)-N-heptan-3-yl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H29BrN6
 1
1
Ki = 3.1 nM
   TI
   LI
   LO
   TS
CP0449381
9-(2-bromo-4,6-dimethoxyphenyl)-N-butyl-N-ethyl-2-methylpurin-6-amine
   Show/Hide
C20H26BrN5O2
 1
1
Ki = 3.5 nM
   TI
   LI
   LO
   TS
CP0464919
Butyl-[9-(2-chloro-4,6-dimethoxy-phenyl)-2,8-dimethyl-9H-purin-6-yl]-ethyl-amine
   Show/Hide
C21H28ClN5O2
 1
1
Ki = 3.5 nM
   TI
   LI
   LO
   TS
CP0498303
9-(2-Bromo-4-isopropyl-phenyl)-6-(1-ethyl-propoxy)-2-methyl-9H-purine
   Show/Hide
C20H25BrN4O
 1
1
Ki = 3.5 nM
   TI
   LI
   LO
   TS
CP0404383
9-(2-bromo-4-propan-2-ylphenyl)-N-heptan-4-yl-2-methylpurin-6-amine
   Show/Hide
C22H30BrN5
 1
1
Ki = 3.6 nM
   TI
   LI
   LO
   TS
CP0460914
3-(2-bromo-4-propan-2-ylphenyl)-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H27BrN6O2
 1
1
Ki = 3.7 nM
   TI
   LI
   LO
   TS
CP0521967
3-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-2,5-dimethylimidazo[4,5-b]pyridin-7-amine
   Show/Hide
C23H31BrN4
 1
1
Ki = 3.9 nM
   TI
   LI
   LO
   TS
CP0518074
N-heptan-4-yl-5-methyl-3-(2,4,6-trimethylphenyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H30N6
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0417281
Allyl-[3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(2-methoxy-ethyl)-amine
   Show/Hide
C20H25BrN6O
 1
1
Ki = 4.3 nM
   TI
   LI
   LO
   TS
CP0456877
9-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-2-methylpurin-6-amine
   Show/Hide
C21H28BrN5
 1
1
Ki = 4.3 nM
   TI
   LI
   LO
   TS
CP0451965
9-(2-bromo-4-propan-2-ylphenyl)-N-hexan-3-yl-2-methylpurin-6-amine
   Show/Hide
C21H28BrN5
 1
1
Ki = 4.4 nM
   TI
   LI
   LO
   TS
CP0504121
Butyl-[3-(2-chloro-4,6-dimethoxy-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-ethyl-amine
   Show/Hide
C19H25ClN6O2
 1
1
Ki = 4.4 nM
   TI
   LI
   LO
   TS
CP0418874
3-(2-bromo-4-propan-2-ylphenyl)-5-methyl-N-nonan-5-yltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C23H33BrN6
 1
1
Ki = 4.5 nM
   TI
   LI
   LO
   TS
CP0391424
1-(3-Bromo-4-{ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amino}-phenyl)-ethanone
   Show/Hide
C22H19BrF3N3O
 1
1
Ki = 4.6 nM
   TI
   LI
   LO
   TS
CP0446162
3-(2-bromo-4-propan-2-ylphenyl)-N-(cyclopropylmethyl)-N-(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H27BrN6O
 1
1
Ki = 4.6 nM
   TI
   LI
   LO
   TS
CP0375832
3-(2-bromo-4-propan-2-ylphenyl)-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-b]pyridin-7-amine
   Show/Hide
C21H28BrN5O2
 1
1
Ki = 4.7 nM
   TI
   LI
   LO
   TS
CP0453252
N,N-bis(2-methoxyethyl)-5-methyl-3-(2-methylsulfanyl-4-propan-2-ylphenyl)triazolo[4,5-b]pyridin-7-amine
   Show/Hide
C22H31N5O2S
 1
1
Ki = 4.7 nM
   TI
   LI
   LO
   TS
CP0540604
Benzyl-[3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(2-methoxy-ethyl)-amine
   Show/Hide
C24H27BrN6O
 1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
CP0436530
9-(2-bromo-4-propan-2-ylphenyl)-N-heptan-3-yl-2-methylpurin-6-amine
   Show/Hide
C22H30BrN5
 1
1
Ki = 5.1 nM
   TI
   LI
   LO
   TS
CP0520511
Butyl-[9-(2-chloro-4,6-dimethoxy-phenyl)-2-methyl-9H-purin-6-yl]-ethyl-amine
   Show/Hide
C20H26ClN5O2
 1
1
Ki = 5.2 nM
   TI
   LI
   LO
   TS
CP0523945
3-(2-bromo-4-propan-2-ylphenyl)-5-methyl-N-pentan-3-yltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6
 1
1
Ki = 5.2 nM
   TI
   LI
   LO
   TS
CP0521966
(1-Ethyl-propyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C19H26N6
 1
1
Ki = 5.7 nM
   TI
   LI
   LO
   TS
CP0534991
(2,4-Dibromo-phenyl)-ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C20H16Br2F3N3
 1
1
Ki = 5.8 nM
   TI
   LI
   LO
   TS
CP0535736
2-{2-[(2-Bromo-4-isopropyl-phenyl)-ethyl-amino]-6-methyl-pyrimidin-4-yl}-benzonitrile
   Show/Hide
C23H23BrN4
 1
1
Ki = 5.8 nM
   TI
   LI
   LO
   TS
CP0501273
9-(2-bromo-4-propan-2-ylphenyl)-N,N-bis(2-methoxyethyl)-2-methylpurin-6-amine
   Show/Hide
C21H28BrN5O2
 1
1
Ki = 5.9 nM
   TI
   LI
   LO
   TS
CP0496563
9-(2-bromo-4-propan-2-ylphenyl)-N,N-dibutyl-2-methylpurin-6-amine
   Show/Hide
C23H32BrN5
 1
1
Ki = 6.1 nM
   TI
   LI
   LO
   TS
CP0523972
9-(2-bromo-4-propan-2-ylphenyl)-N,N-bis(2-methoxyethyl)-2,8-dimethylpurin-6-amine
   Show/Hide
C22H30BrN5O2
 1
1
Ki = 6.7 nM
   TI
   LI
   LO
   TS
CP0425314
3-(2-Bromo-4-isopropyl-phenyl)-7-(2-methoxy-1-methoxymethyl-ethoxy)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C19H24BrN5O3
 1
1
Ki = 7.1 nM
   TI
   LI
   LO
   TS
CP0447215
Bis-(2-methoxy-ethyl)-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine
   Show/Hide
C24H34N4O2
 1
1
Ki = 7.1 nM
   TI
   LI
   LO
   TS
CP0475685
(1-Methyl-butyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C19H26N6
 1
1
Ki = 7.1 nM
   TI
   LI
   LO
   TS
CP0548635
3-(2,4-dibromophenyl)-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C17H20Br2N6O2
 1
1
Ki = 7.4 nM
   TI
   LI
   LO
   TS
CP0534472
3-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H27BrN6
 1
1
Ki = 7.5 nM
   TI
   LI
   LO
   TS
CP0523969
(1-Ethyl-pentyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C21H30N6
 1
1
Ki = 7.6 nM
   TI
   LI
   LO
   TS
CP0493809
(2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-naphthalen-1-yl-pyrimidin-2-yl)-amine
   Show/Hide
C26H26BrN3
 1
1
Ki = 7.8 nM
   TI
   LI
   LO
   TS
CP0402768
9-(2-bromo-4-propan-2-ylphenyl)-N-(1-methoxypentan-3-yl)-2-methylpurin-6-amine
   Show/Hide
C21H28BrN5O
 1
1
Ki = 8 nM
   TI
   LI
   LO
   TS
CP0431695
(4-Biphenyl-2-yl-6-methyl-pyrimidin-2-yl)-(2-bromo-4-isopropyl-phenyl)-ethyl-amine
   Show/Hide
C28H28BrN3
 1
1
Ki = 8.4 nM
   TI
   LI
   LO
   TS
CP0506460
(2-Bromo-4,6-dimethoxy-phenyl)-ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C22H21BrF3N3O2
 1
1
Ki = 8.6 nM
   TI
   LI
   LO
   TS
CP0275845
2-N-(2-bromo-4-propan-2-ylphenyl)-2-N-ethyl-6-methyl-4-N,4-N-dipropylpyrimidine-2,4-diamine
   Show/Hide
C22H33BrN4
 1
1
Ki = 9 nM
   TI
   LI
   LO
   TS
CP0506558
(2-Bromo-4,6-dimethoxy-phenyl)-[4-(2-chloro-phenyl)-6-methyl-pyrimidin-2-yl]-ethyl-amine
   Show/Hide
C21H21BrClN3O2
 1
1
Ki = 9.1 nM
   TI
   LI
   LO
   TS
CP0520450
9-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-N-(2-methoxyethyl)-2-methylpurin-6-amine
   Show/Hide
C20H26BrN5O
 1
1
Ki = 9.2 nM
   TI
   LI
   LO
   TS
CP0535749
2-Bromo-N*1*-ethyl-6-methoxy-N*4*,N*4*-dimethyl-N*1*-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-benzene-1,4-diamine
   Show/Hide
C23H24BrF3N4O
 1
1
Ki = 9.4 nM
   TI
   LI
   LO
   TS
CP0534511
9-(2-Bromo-4-isopropyl-phenyl)-6-(1-methoxymethyl-propoxy)-2-methyl-9H-purine
   Show/Hide
C20H25BrN4O2
 1
1
Ki = 9.7 nM
   TI
   LI
   LO
   TS
CP0530250
3-(2-bromo-4-propan-2-ylphenyl)-N,N-bis(2-methoxyethyl)-2,5-dimethylimidazo[4,5-b]pyridin-7-amine
   Show/Hide
C23H31BrN4O2
 1
1
Ki = 9.8 nM
   TI
   LI
   LO
   TS
CP0439194
(2-Bromo-4-isopropyl-phenyl)-[4-(2,6-dichloro-phenyl)-6-methyl-pyrimidin-2-yl]-ethyl-amine
   Show/Hide
C22H22BrCl2N3
 1
1
Ki = 10.1 nM
   TI
   LI
   LO
   TS
CP0464458
3-(2-bromo-4-propan-2-ylphenyl)-N-(1,3-dimethoxypropan-2-yl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6O2
 1
1
Ki = 10.3 nM
   TI
   LI
   LO
   TS
CP0464248
3-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-N-(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6O
 1
1
Ki = 10.5 nM
   TI
   LI
   LO
   TS
CP0538772
3-[2-bromo-4-(dimethylamino)phenyl]-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H26BrN7O2
 1
1
Ki = 10.5 nM
   TI
   LI
   LO
   TS
CP0464434
3-(2-bromo-4-methylsulfanylphenyl)-N-butyl-N-ethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H23BrN6S
 1
1
Ki = 10.6 nM
   TI
   LI
   LO
   TS
CP0384052
(2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2,4,6-trimethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C25H30BrN3
 1
1
Ki = 11.2 nM
   TI
   LI
   LO
   TS
CP0480633
3-(2-bromo-4-propan-2-ylphenyl)-N-(1-methoxybutan-2-yl)-N,5-dimethyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H27BrN6O
 1
1
Ki = 11.2 nM
   TI
   LI
   LO
   TS
CP0465378
9-(2-bromo-4-propan-2-ylphenyl)-N,N-diethyl-2-methylpurin-6-amine
   Show/Hide
C19H24BrN5
 1
1
Ki = 12.4 nM
   TI
   LI
   LO
   TS
CP0491796
(2-Bromo-4-isopropyl-phenyl)-[4-(2-chloro-phenyl)-6-methyl-pyrimidin-2-yl]-ethyl-amine
   Show/Hide
C22H23BrClN3
 1
1
Ki = 13.5 nM
   TI
   LI
   LO
   TS
CP0526916
(2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-phenyl-pyrimidin-2-yl)-amine
   Show/Hide
C21H22BrN3O2
 1
1
Ki = 13.9 nM
   TI
   LI
   LO
   TS
CP0451964
N,N-bis(2-methoxyethyl)-5-methyl-3-(2-methylsulfanyl-4-propan-2-ylphenyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H30N6O2S
 1
1
Ki = 15.3 nM
   TI
   LI
   LO
   TS
CP0497797
Butyl-[3-(4-dimethylamino-2-trifluoromethyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-ethyl-amine
   Show/Hide
C20H26F3N7
 1
1
Ki = 15.4 nM
   TI
   LI
   LO
   TS
CP0391398
(2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(3-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C23H23BrF3N3
 1
1
Ki = 17.4 nM
   TI
   LI
   LO
   TS
CP0504147
(2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-o-tolyl-pyrimidin-2-yl)-amine
   Show/Hide
C23H26BrN3
 1
1
Ki = 18.4 nM
   TI
   LI
   LO
   TS
CP0507622
2-[3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamino]-butyric acid methyl ester
   Show/Hide
C19H23BrN6O2
 1
1
Ki = 19.4 nM
   TI
   LI
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   TS
CP0436358
Butyl-[3-(2,4-dibromo-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-ethyl-amine
   Show/Hide
C17H20Br2N6
 1
1
Ki = 20.4 nM
   TI
   LI
   LO
   TS
CP0496753
(2-Bromo-4-methanesulfonyl-phenyl)-ethyl-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C21H19BrF3N3O2S
 1
1
Ki = 20.6 nM
   TI
   LI
   LO
   TS
CP0375831
Bis-(2-methoxy-ethyl)-[2-methyl-9-(2,4,6-trimethyl-phenyl)-9H-purin-6-yl]-amine
   Show/Hide
C21H29N5O2
 1
1
Ki = 20.7 nM
   TI
   LI
   LO
   TS
CP0475653
N-ethyl-N-(2-methoxyethyl)-5-methyl-3-(2,4,6-trimethylphenyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H26N6O
 1
1
Ki = 20.7 nM
   TI
   LI
   LO
   TS
CP0458723
3-(2-chloro-4,6-dimethoxyphenyl)-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25ClN6O4
 1
1
Ki = 21 nM
   TI
   LI
   LO
   TS
CP0452019
3-(2-bromo-4-propan-2-ylphenyl)-N-(1,3-dimethoxypropan-2-yl)-N,5-dimethyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H27BrN6O2
 1
1
Ki = 21.3 nM
   TI
   LI
   LO
   TS
CP0503290
Butyl-[8-butyl-9-(2-chloro-4,6-dimethoxy-phenyl)-2-methyl-9H-purin-6-yl]-ethyl-amine
   Show/Hide
C24H34ClN5O2
 1
1
Ki = 22 nM
   TI
   LI
   LO
   TS
CP0427044
(2-Bromo-4-isopropyl-phenyl)-ethyl-[4-(2-fluoro-phenyl)-6-methyl-pyrimidin-2-yl]-amine
   Show/Hide
C22H23BrFN3
 1
1
Ki = 23.4 nM
   TI
   LI
   LO
   TS
CP0460890
3-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H26F3N7O2
 1
1
Ki = 23.5 nM
   TI
   LI
   LO
   TS
CP0412485
9-(2-chloro-4,6-dimethoxyphenyl)-N-(2-methoxyethyl)-N-(3-methoxypropyl)-2-methylpurin-6-amine
   Show/Hide
C21H28ClN5O4
 1
1
Ki = 23.8 nM
   TI
   LI
   LO
   TS
CP0505262
(2-Bromo-4-isopropyl-phenyl)-[4-(2-bromo-phenyl)-6-methyl-pyrimidin-2-yl]-ethyl-amine
   Show/Hide
C22H23Br2N3
 1
1
Ki = 24 nM
   TI
   LI
   LO
   TS
CP0412475
Bis-(2-methoxy-ethyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C20H28N6O2
 1
1
Ki = 24.1 nM
   TI
   LI
   LO
   TS
CP0497931
(2-Bromo-4-isopropyl-6-methyl-phenyl)-ethyl-[4-methyl-6-(2,4,6-trimethyl-pyridin-3-yl)-pyrimidin-2-yl]-amine
   Show/Hide
C25H31BrN4
 1
1
Ki = 24.9 nM
   TI
   LI
   LO
   TS
CP0449838
Butyl-ethyl-[2-methyl-9-(2,4,6-trimethyl-phenyl)-9H-purin-6-yl]-amine
   Show/Hide
C21H29N5
 1
1
Ki = 25 nM
   TI
   LI
   LO
   TS
CP0404382
3-(2-bromo-4-propan-2-ylphenyl)-N,N-diethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H23BrN6
 1
1
Ki = 25.3 nM
   TI
   LI
   LO
   TS
CP0418548
2-[3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamino]-butan-1-ol
   Show/Hide
C18H23BrN6O
 1
1
Ki = 25.3 nM
   TI
   LI
   LO
   TS
CP0465280
2-[2,5,6-Trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino]-butan-1-ol
   Show/Hide
C22H30N4O
 1
1
Ki = 27.3 nM
   TI
   LI
   LO
   TS
CP0500974
Butyl-ethyl-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C20H28N6
 1
1
Ki = 27.5 nM
   TI
   LI
   LO
   TS
CP0507650
(1-Methoxymethyl-2-phenyl-ethyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C24H28N6O
 1
1
Ki = 27.7 nM
   TI
   LI
   LO
   TS
CP0404223
3-(2-bromo-4,6-dimethoxyphenyl)-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6O4
 1
1
Ki = 28.3 nM
   TI
   LI
   LO
   TS
CP0538236
Butyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine
   Show/Hide
C22H30N4
 1
1
Ki = 29 nM
   TI
   LI
   LO
   TS
CP0518081
9-(2-bromo-4,6-dimethoxyphenyl)-N,N-bis(2-methoxyethyl)-2-methylpurin-6-amine
   Show/Hide
C20H26BrN5O4
 1
1
Ki = 31.3 nM
   TI
   LI
   LO
   TS
CP0521965
3-(2-bromo-4-propan-2-ylphenyl)-N,N-dibutyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C22H31BrN6
 1
1
Ki = 32.5 nM
   TI
   LI
   LO
   TS
CP0401225
3-[2-bromo-4-(trifluoromethoxy)phenyl]-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H20BrF3N6O3
 1
1
Ki = 33.2 nM
   TI
   LI
   LO
   TS
CP0487365
1-{3-Bromo-4-[7-(butyl-ethyl-amino)-5-methyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-phenyl}-ethanone
   Show/Hide
C19H23BrN6O
 1
1
Ki = 33.7 nM
   TI
   LI
   LO
   TS
CP0418545
3-(2-bromo-4-propan-2-ylphenyl)-N-(1-methoxy-3-phenylpropan-2-yl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C24H27BrN6O
 1
1
Ki = 36.7 nM
   TI
   LI
   LO
   TS
CP0406378
2-N-[3-(2-bromo-4-propan-2-ylphenyl)-5-methyltriazolo[4,5-d]pyrimidin-7-yl]-1-N,1-N-dimethylpentane-1,2-diamine
   Show/Hide
C21H30BrN7
 1
1
Ki = 38.7 nM
   TI
   LI
   LO
   TS
CP0488141
3-(2-Bromo-4-isopropyl-phenyl)-7-(2-ethoxy-1-ethoxymethyl-ethoxy)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C21H28BrN5O3
 1
1
Ki = 39.7 nM
   TI
   LI
   LO
   TS
CP0496609
3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-7-piperidin-1-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C19H23BrN6
 1
1
Ki = 46 nM
   TI
   LI
   LO
   TS
CP0545049
3-[2-bromo-6-(dimethylamino)-4-methoxyphenyl]-N,N-bis(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H28BrN7O3
 1
1
Ki = 48.2 nM
   TI
   LI
   LO
   TS
CP0485169
3-(2-bromo-4-propan-2-ylphenyl)-N-(2-methoxyethyl)-5-methyl-N-(pyridin-3-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C23H26BrN7O
 1
1
Ki = 48.5 nM
   TI
   LI
   LO
   TS
CP0449366
(2-Bromo-4,6-dimethoxy-phenyl)-ethyl-[4-(2-methoxy-phenyl)-6-methyl-pyrimidin-2-yl]-amine
   Show/Hide
C22H24BrN3O3
 1
1
Ki = 54.8 nM
   TI
   LI
   LO
   TS
CP0404463
(1-Methoxymethyl-propyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C19H26N6O
 1
1
Ki = 59.4 nM
   TI
   LI
   LO
   TS
CP0404163
2-[[3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(2-methoxy-ethyl)-amino]-ethanol
   Show/Hide
C19H25BrN6O2
 1
1
Ki = 64 nM
   TI
   LI
   LO
   TS
CP0392207
Butyl-ethyl-[5-methyl-3-(2,4,6-trimethyl-pyridin-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C19H27N7
 1
1
Ki = 65 nM
   TI
   LI
   LO
   TS
CP0520230
3-(2-bromo-4-propan-2-ylphenyl)-N-(2-methoxyethyl)-N-(3-methoxypropyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H29BrN6O2
 1
1
Ki = 66.9 nM
   TI
   LI
   LO
   TS
CP0466832
3-(2-bromo-4-propan-2-ylphenyl)-N-butyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H23BrN6
 1
1
Ki = 69.6 nM
   TI
   LI
   LO
   TS
CP0457312
(2-Bromo-4-isopropyl-phenyl)-[4-(2-dimethylamino-phenyl)-6-methyl-pyrimidin-2-yl]-ethyl-amine
   Show/Hide
C24H29BrN4
 1
1
Ki = 78.2 nM
   TI
   LI
   LO
   TS
CP0504667
Butyl-ethyl-[3-(4-isopropyl-2-methanesulfonyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-b]pyridin-7-yl]-amine
   Show/Hide
C22H31N5O2S
 1
1
Ki = 83 nM
   TI
   LI
   LO
   TS
CP0467100
(4-Biphenyl-3-yl-6-methyl-pyrimidin-2-yl)-(2-bromo-4-isopropyl-phenyl)-ethyl-amine
   Show/Hide
C28H28BrN3
 1
1
Ki = 84.6 nM
   TI
   LI
   LO
   TS
CP0449837
3-(2-bromo-4-methylsulfonylphenyl)-N-butyl-N-ethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H23BrN6O2S
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0399751
(2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-phenyl-pyrimidin-2-yl)-amine
   Show/Hide
C22H24BrN3
 1
1
Ki = 109 nM
   TI
   LI
   LO
   TS
CP0428654
3-(2-bromo-4-propan-2-ylphenyl)-N-cyclopentyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H23BrN6
 1
1
Ki = 120 nM
   TI
   LI
   LO
   TS
CP0525456
3-(2-bromo-4-propan-2-ylphenyl)-N-(1,3-dimethoxypropan-2-yl)-N-ethyl-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H29BrN6O2
 1
1
Ki = 123 nM
   TI
   LI
   LO
   TS
CP0441415
Butyl-[9-(2-chloro-4,6-dimethoxy-phenyl)-2-methyl-8-phenyl-9H-purin-6-yl]-ethyl-amine
   Show/Hide
C26H30ClN5O2
 1
1
Ki = 133 nM
   TI
   LI
   LO
   TS
CP0503509
3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-7-pyrrolidin-1-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine
   Show/Hide
C18H21BrN6
 1
1
Ki = 194 nM
   TI
   LI
   LO
   TS
CP0485170
3-(2-bromo-4-propan-2-ylphenyl)-N-(1-methoxy-2-methylpropan-2-yl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6O
 1
1
Ki = 195 nM
   TI
   LI
   LO
   TS
CP0397986
2,5,6-Trimethyl-4-morpholin-4-yl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C22H28N4O
 1
1
Ki = 201 nM
   TI
   LI
   LO
   TS
CP0507722
3-(2-bromo-4-propan-2-ylphenyl)-N,N-bis(2-methoxyethyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6O2
 1
1
Ki = 203 nM
   TI
   LI
   LO
   TS
CP0510026
9-(2-bromo-4-propan-2-ylphenyl)-N-(2-methoxyethyl)-2-methylpurin-6-amine
   Show/Hide
C18H22BrN5O
 1
1
Ki = 210 nM
   TI
   LI
   LO
   TS
CP0415377
(2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-pyridin-2-yl-pyrimidin-2-yl)-amine
   Show/Hide
C20H21BrN4O2
 1
1
Ki = 222 nM
   TI
   LI
   LO
   TS
CP0493482
(2-Bromo-4,6-dimethoxy-phenyl)-ethyl-(4-methyl-6-pyridin-3-yl-pyrimidin-2-yl)-amine
   Show/Hide
C20H21BrN4O2
 1
1
Ki = 229 nM
   TI
   LI
   LO
   TS
CP0506121
2-[3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamino]-pentanoic acid dimethylamide
   Show/Hide
C21H28BrN7O
 1
1
Ki = 235 nM
   TI
   LI
   LO
   TS
CP0425313
3-(2-bromo-4-propan-2-ylphenyl)-N-(2-methoxyethyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C17H21BrN6O
 1
1
Ki = 242 nM
   TI
   LI
   LO
   TS
CP0403837
3-(2-bromo-4-propan-2-ylphenyl)-N-butyl-N-ethyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C19H25BrN6
 1
1
Ki = 287 nM
   TI
   LI
   LO
   TS
CP0490336
3-(2-bromo-4-propan-2-ylphenyl)-N-(3-methoxypropyl)-5-methyltriazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C18H23BrN6O
 1
1
Ki = 291 nM
   TI
   LI
   LO
   TS
CP0380797
(2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-methylamino-phenyl)-pyrimidin-2-yl]-amine
   Show/Hide
C23H27BrN4
 1
1
Ki = 369 nM
   TI
   LI
   LO
   TS
CP0507692
Bis-(2-methoxy-ethyl)-[5-methyl-3-(2,4,6-trimethyl-pyridin-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C19H27N7O2
 1
1
Ki = 416 nM
   TI
   LI
   LO
   TS
CP0496102
N,N-bis(2-methoxyethyl)-5-methyl-3-(2-methylsulfonyl-4-propan-2-ylphenyl)triazolo[4,5-b]pyridin-7-amine
   Show/Hide
C22H31N5O4S
 1
1
Ki = 476 nM
   TI
   LI
   LO
   TS
CP0448217
(2-Bromo-4-isopropyl-phenyl)-ethyl-{4-methyl-6-[2-(1H-tetrazol-5-yl)-phenyl]-pyrimidin-2-yl}-amine
   Show/Hide
C23H24BrN7
 1
1
Ki = 662 nM
   TI
   LI
   LO
   TS
CP0397964
N,N-bis(2-methoxyethyl)-5-methyl-3-(2-methylsulfonyl-4-propan-2-ylphenyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C21H30N6O4S
 1
1
Ki = 1026 nM
   TI
   LI
   LO
   TS
CP0520231
(2-Methoxy-ethyl)-[5-methyl-3-(2,4,6-trimethyl-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine
   Show/Hide
C17H22N6O
 1
1
Ki = 1204 nM
   TI
   LI
   LO
   TS
CP0440125
4-(2-aminophenyl)-N-(2-bromo-4-propan-2-ylphenyl)-N-ethyl-6-methylpyrimidin-2-amine
   Show/Hide
C22H25BrN4
 1
1
Ki = 2359 nM
   TI
   LI
   LO
   TS
CP0453061
N'-[9-(2-bromo-4-propan-2-ylphenyl)-2-methylpurin-6-yl]-N'-ethyl-N,N-dimethylethane-1,2-diamine
   Show/Hide
C21H29BrN6
 1
1
Ki = 2665 nM
   TI
   LI
   LO
   TS
CP0518326
2-[[3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-(2-hydroxy-ethyl)-amino]-ethanol
   Show/Hide
C18H23BrN6O2
 1
1
Ki = 3460 nM
   TI
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   TS
CP0502426
2-{2-[(2-Bromo-4-isopropyl-phenyl)-ethyl-amino]-6-methyl-pyrimidin-4-yl}-benzoic acid
   Show/Hide
C23H24BrN3O2
 1
1
Ki = 3536 nM
   TI
   LI
   LO
   TS
CP0402107
N,N-bis(2-methoxyethyl)-5-methyl-3-(4-propan-2-ylphenyl)triazolo[4,5-d]pyrimidin-7-amine
   Show/Hide
C20H28N6O2
 1
1
Ki = 3918 nM
   TI
   LI
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   TS