Brief Information of the Compound and Protein
Compound Name
2-Bromo-N*1*-ethyl-6-methoxy-N*4*,N*4*-dimethyl-N*1*-[4-methyl-6-(2-trifluoromethyl-phenyl)-pyrimidin-2-yl]-benzene-1,4-diamine
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PubChem ID
CID: 18691325
Canonical SMILES
CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1c(Br)cc(cc1OC)N(C)C
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Compound Formula C23H24BrF3N4O
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
Ki = 9.4 nM
   TI
   LI
   LO
   TS