| Compound ID |
Compound Name |
Compound Formula |
|
CP0444527
|
3-pyrazin-2-yl-N-(3-tricyclo[3.3.1.03,7]nonanyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
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|
C22H25N5O2
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0547775
|
N-(1-bicyclo[2.2.2]octanyl)-3-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C21H25N5O3
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0547776
|
5-[3-(2-methylbutan-2-yl)-1,2,4-oxadiazol-5-yl]-3-pyrazin-2-yl-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene
Show/Hide
|
C19H22N6O2
|
1
|
| 1 |
EC50 = 0.04 nM
|
|
|
|
CP0562120
|
3-pyrazin-2-yl-N-[1-(trifluoromethyl)cyclobutyl]-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C18H18F3N5O2
|
1
|
| 1 |
EC50 = 0.04 nM
|
|
|
|
CP0534087
|
N-(1-bicyclo[1.1.1]pentanyl)-3-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C18H19N5O3
|
1
|
| 1 |
EC50 = 0.05 nM
|
|
|
|
CP0531513
|
5-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-3-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene
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|
C18H20N6O2S
|
1
|
| 1 |
EC50 = 0.06 nM
|
|
|
|
CP0444528
|
3-(2,4-difluorophenyl)-N-(3-tricyclo[3.3.1.03,7]nonanyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C24H25F2N3O2
|
1
|
| 1 |
EC50 = 0.08 nM
|
|
|
|
CP0569296
|
8-[(6aR,9R,10aR)-1-hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-3-yl]-8-methylnonanenitrile
Show/Hide
|
C26H39NO3
|
1
|
| 1 |
EC50 = 0.088 nM
|
|
|
|
CP0547777
|
(1S,8R)-N-[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]-3-pyrazin-2-yl-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C19H25N5O3
|
1
|
| 1 |
EC50 = 0.09 nM
|
|
|
|
CP0570671
|
(6aR,9R,10aR)-3-(8-azido-2-methyloctan-2-yl)-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Show/Hide
|
C25H39N3O3
|
1
|
| 1 |
EC50 = 0.098 nM
|
|
|
|
CP0048192
|
2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol
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|
C24H40O3
|
7
|
| 1 |
EC50 = 0.26 nM
|
|
|
| 2 |
EC50 = 1.13 nM
|
|
|
| 3 |
EC50 = 3.9 nM
|
|
|
| 4 |
EC50 = 20 nM
|
|
|
| 5 |
Kd = 0.5 nM
|
|
|
| 6 |
Ki = 0.52 nM
|
|
|
| 7 |
Ki = 9.26 nM
|
|
|
|
CP0474271
|
(2R,4R)-9-[(4-fluorophenyl)methyl]-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C24H24FN3O
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0576318
|
7-[1-[(6aR,9R,10aR)-1-hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-3-yl]cyclopentyl]heptanenitrile
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|
C28H41NO3
|
1
|
| 1 |
EC50 = 0.31 nM
|
|
|
|
CP0569295
|
(6aR,9R,10aR)-9-(hydroxymethyl)-3-[1-(7-isothiocyanatoheptyl)cyclopentyl]-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
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|
C29H43NO3S
|
1
|
| 1 |
EC50 = 0.43 nM
|
|
|
|
CP0551146
|
(6aR,9R,10aR)-9-(hydroxymethyl)-3-[1-(6-isothiocyanatohexyl)cyclopentyl]-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Show/Hide
|
C28H41NO3S
|
1
|
| 1 |
EC50 = 0.52 nM
|
|
|
|
CP0547774
|
(1R,8S)-N-[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]-3-pyrazin-2-yl-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C19H25N5O3
|
1
|
| 1 |
EC50 = 0.56 nM
|
|
|
|
CP0419762
|
N-tert-butyl-3-(2,4-difluorophenyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C19H21F2N3O2
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0421039
|
7-fluoro-2-(3-fluorophenyl)-3-[1-(2-fluorophenyl)-2-nitroethyl]-1H-indole
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|
C22H15F3N2O2
|
6
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
EC50 = 3.9 nM
|
|
|
| 3 |
EC50 = 9.1 nM
|
|
|
| 4 |
EC50 = 510 nM
|
|
|
| 5 |
EC50 = 3500 nM
|
|
|
| 6 |
EC50 > 10000 nM
|
|
|
|
CP0404396
|
3-ethyl-5-isothiocyanato-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
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|
C25H28N4OS
|
2
|
| 1 |
EC50 = 2.09 nM
|
|
|
| 2 |
EC50 = 174 nM
|
|
|
|
CP0410458
|
(2R,4R)-9-(oxan-4-ylmethyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H29N3O2
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0421043
|
6-fluoro-2-(3-fluorophenyl)-3-[1-(2-fluorophenyl)-2-nitroethyl]-1H-indole
Show/Hide
|
C22H15F3N2O2
|
6
|
| 1 |
EC50 = 2.2 nM
|
|
|
| 2 |
EC50 = 4.3 nM
|
|
|
| 3 |
EC50 = 28 nM
|
|
|
| 4 |
EC50 = 190 nM
|
|
|
| 5 |
EC50 = 750 nM
|
|
|
| 6 |
EC50 = 1600 nM
|
|
|
|
CP0914616
|
3-(2-nitro-1-(o-tolyl)ethyl)-2-phenyl-1H-indole
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|
C23H20N2O2
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 57 nM
|
|
|
|
CP0228439
|
1-(4-chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea
Show/Hide
|
C22H21ClN4O
|
3
|
| 1 |
EC50 = 3.84 nM
|
|
|
| 2 |
EC50 = 70.8 nM
|
|
|
| 3 |
EC50 = 270 nM
|
|
|
|
CP0410457
|
(2R,4R)-9-[2-(oxan-4-yl)ethyl]-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0495408
|
(6aR,9R,10aR)-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyloctan-2-yl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Show/Hide
|
C26H39NO3S
|
1
|
| 1 |
EC50 = 5.8 nM
|
|
|
|
CP0550412
|
(2R,4R)-9-(2,2-dimethylpropyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H29N3O
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
|
CP0421042
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
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|
C22H18N2O2
|
10
|
| 1 |
EC50 = 8.1 nM
|
|
|
| 2 |
EC50 = 78 nM
|
|
|
| 3 |
EC50 = 200 nM
|
|
|
| 4 |
EC50 = 230 nM
|
|
|
| 5 |
EC50 = 260 nM
|
|
|
| 6 |
EC50 = 303 nM
|
|
|
| 7 |
EC50 = 629 nM
|
|
|
| 8 |
EC50 = 650 nM
|
|
|
| 9 |
EC50 = 940 nM
|
|
|
| 10 |
EC50 = 1200 nM
|
|
|
|
CP0387212
|
5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
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|
C24H28ClN3O
|
3
|
| 1 |
EC50 = 9.05 nM
|
|
|
| 2 |
EC50 = 324 nM
|
|
|
| 3 |
IC50 = 2 nM
|
|
|
|
CP0421041
|
3-[1-(3-fluoropyridin-2-yl)-2-nitroethyl]-2-phenyl-1H-indole
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|
C21H16FN3O2
|
4
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 1900 nM
|
|
|
| 3 |
EC50 = 3300 nM
|
|
|
| 4 |
EC50 > 10000 nM
|
|
|
|
CP0375332
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H21F2N3O
|
1
|
| 1 |
EC50 = 15.6 nM
|
|
|
|
CP0423016
|
2-phenyl-3-[(1R)-3,3,3-trifluoro-1-thiophen-2-ylpropyl]-1H-indole-6-carbonitrile
Show/Hide
|
C22H15F3N2S
|
4
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
EC50 = 29 nM
|
|
|
| 3 |
EC50 = 363 nM
|
|
|
| 4 |
EC50 = 828 nM
|
|
|
|
CP0200649
|
6-methyl-3-(2-nitro-1-thiophen-2-ylethyl)-2-phenyl-1H-indole
Show/Hide
|
C21H18N2O2S
|
6
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
EC50 = 32 nM
|
|
|
| 3 |
EC50 = 33 nM
|
|
|
| 4 |
EC50 = 283 nM
|
|
|
| 5 |
EC50 = 379 nM
|
|
|
| 6 |
EC50 = 777 nM
|
|
|
|
CP0955271
|
3-(1-(2-chlorophenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H17ClN2O2
|
2
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
EC50 = 1241 nM
|
|
|
|
CP0410460
|
(2R,4R)-9-(2-morpholin-4-ylethyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H30N4O2
|
1
|
| 1 |
EC50 = 19.1 nM
|
|
|
|
CP0482567
|
7-fluoro-3-[1-(2-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
|
C22H16F2N2O2
|
2
|
| 1 |
EC50 = 21 nM
|
|
|
| 2 |
EC50 = 680 nM
|
|
|
|
CP0397073
|
(2R,4R)-9-(2,4-dichlorophenyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H21Cl2N3O
|
1
|
| 1 |
EC50 = 21.7 nM
|
|
|
|
CP0534280
|
7-fluoro-3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
2
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
EC50 = 750 nM
|
|
|
|
CP0363373
|
5-azido-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H28N6O
|
2
|
| 1 |
EC50 = 28.2 nM
|
|
|
| 2 |
EC50 = 389 nM
|
|
|
|
CP0366932
|
1-(4-azidophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea
Show/Hide
|
C22H21N7O
|
2
|
| 1 |
EC50 = 28.2 nM
|
|
|
| 2 |
EC50 = 166 nM
|
|
|
|
CP0956143
|
3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole
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|
C20H16N2O2S
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
EC50 = 584 nM
|
|
|
|
CP0880785
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-indazole-3-carboxamide
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0473688
|
2-phenyl-3-[(1S)-3,3,3-trifluoro-1-thiophen-2-ylpropyl]-1H-indole-6-carbonitrile
Show/Hide
|
C22H15F3N2S
|
4
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
EC50 = 76 nM
|
|
|
| 3 |
EC50 = 342 nM
|
|
|
| 4 |
EC50 = 1206 nM
|
|
|
|
CP0404435
|
1-(4-isothiocyanatophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea
Show/Hide
|
C23H21N5OS
|
2
|
| 1 |
EC50 = 42.9 nM
|
|
|
| 2 |
EC50 = 118 nM
|
|
|
|
CP0375333
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-2-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H20F2N4O
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0404194
|
1-(4-chlorophenyl)-3-[3-(3-pyrrolidin-1-ylphenyl)phenyl]urea
Show/Hide
|
C23H22ClN3O
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0434022
|
3-[1-(2-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
3
|
| 1 |
EC50 = 43 nM
|
|
|
| 2 |
EC50 = 782 nM
|
|
|
| 3 |
EC50 = 1060 nM
|
|
|
|
CP0914618
|
2-(1-(6-methyl-2-phenyl-1H-indol-3-yl)-2-nitroethyl)thiazole
Show/Hide
|
C20H17N3O2S
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
EC50 = 163 nM
|
|
|
|
CP0410461
|
(2R,4R)-N-(2-phenylpropan-2-yl)-9-propan-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0493964
|
6-fluoro-3-[1-(2-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
|
C22H16F2N2O2
|
2
|
| 1 |
EC50 = 58 nM
|
|
|
| 2 |
EC50 = 1140 nM
|
|
|
|
CP0212787
|
3-(2-azidoethyl)-5-chloro-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H27ClN6O
|
2
|
| 1 |
EC50 = 64 nM
|
|
|
| 2 |
EC50 = 1120 nM
|
|
|
|
CP0045801
|
(10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C21H30O2
|
3
|
| 1 |
EC50 = 77.5 nM
|
|
|
| 2 |
Ki = 3.88 nM
|
|
|
| 3 |
Ki = 22 nM
|
|
|
|
CP0534281
|
2-(3-fluorophenyl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C22H17FN2O2
|
2
|
| 1 |
EC50 = 80 nM
|
|
|
| 2 |
EC50 = 1300 nM
|
|
|
|
CP0456392
|
(2R,4R)-9-tert-butyl-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C21H27N3O
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0951082
|
3-(2-nitro-1-phenylethyl)-2-(thiophen-3-yl)-1H-indole
Show/Hide
|
C20H16N2O2S
|
2
|
| 1 |
EC50 = 87 nM
|
|
|
| 2 |
EC50 = 320 nM
|
|
|
|
CP0379230
|
(9S)-6,6,9-trimethyl-3-pentyl-7,8,9,10-tetrahydrobenzo[c]chromen-1-ol
Show/Hide
|
C21H30O2
|
2
|
| 1 |
EC50 = 87.5 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0536787
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-2-fluorobenzamide
Show/Hide
|
C29H23Cl2FN6O
|
1
|
| 1 |
EC50 = 94.8 nM
|
|
|
|
CP0951066
|
2-(furan-3-yl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C20H16N2O3
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
EC50 > 1000 nM
|
|
|
|
CP0474275
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclobutyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C19H19F2N3O2
|
1
|
| 1 |
EC50 = 105 nM
|
|
|
|
CP0533583
|
6-fluoro-3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
2
|
| 1 |
EC50 = 110 nM
|
|
|
| 2 |
EC50 = 1100 nM
|
|
|
|
CP0960752
|
3-(2-nitro-1-phenylethyl)-2-(thiophen-2-yl)-1H-indole
Show/Hide
|
C20H16N2O2S
|
2
|
| 1 |
EC50 = 110 nM
|
|
|
| 2 |
EC50 = 170 nM
|
|
|
|
CP0926447
|
3-(2-nitro-1-(thiophen-3-yl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H16N2O2S
|
2
|
| 1 |
EC50 = 119 nM
|
|
|
| 2 |
EC50 = 1609 nM
|
|
|
|
CP0442882
|
N-(1-adamantyl)-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C24H25N3O
|
1
|
| 1 |
EC50 = 123 nM
|
|
|
|
CP0375369
|
(9R)-6,6,9-trimethyl-3-pentyl-7,8,9,10-tetrahydrobenzo[c]chromen-1-ol
Show/Hide
|
C21H30O2
|
2
|
| 1 |
EC50 = 126.5 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
|
CP0952514
|
3-(2-nitro-1-(3-(trifluoromethyl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C23H17F3N2O2
|
2
|
| 1 |
EC50 = 127 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0484159
|
4-fluoro-3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
2
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
EC50 = 900 nM
|
|
|
|
CP0959252
|
2-(furan-2-yl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C20H16N2O3
|
2
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
EC50 = 2100 nM
|
|
|
|
CP0426658
|
N-[1-[8-(2-chlorophenyl)-9-[6-(difluoromethoxy)pyridin-3-yl]purin-6-yl]piperidin-4-yl]-3,4-difluorobenzenesulfonamide
Show/Hide
|
C28H22ClF4N7O3S
|
1
|
| 1 |
EC50 = 131.9 nM
|
|
|
|
CP0951069
|
2-(benzo[b]thiophen-2-yl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C24H18N2O2S
|
2
|
| 1 |
EC50 = 150 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0471759
|
1-[2-phenyl-3-(3,3,3-trifluoro-1-thiophen-2-ylpropyl)-1H-indol-6-yl]ethanone
Show/Hide
|
C23H18F3NOS
|
2
|
| 1 |
EC50 = 158 nM
|
|
|
| 2 |
EC50 = 741 nM
|
|
|
|
CP0435430
|
2-phenyl-3-(3,3,3-trifluoro-1-thiophen-2-ylpropyl)-1H-indole-6-carbonitrile
Show/Hide
|
C22H15F3N2S
|
2
|
| 1 |
EC50 = 177 nM
|
|
|
| 2 |
EC50 = 647 nM
|
|
|
|
CP0921023
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-pyrrolo[3,2-b]-pyridine-3-carboxamide
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0538548
|
5-fluoro-3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
2
|
| 1 |
EC50 = 191 nM
|
|
|
| 2 |
EC50 = 740 nM
|
|
|
|
CP0950864
|
2-(2-nitro-1-(2-phenyl-1H-indol-3-yl)ethyl)thiazole
Show/Hide
|
C19H15N3O2S
|
2
|
| 1 |
EC50 = 192 nM
|
|
|
| 2 |
EC50 = 331 nM
|
|
|
|
CP0952512
|
3-(1-(4-(tert-butyl)phenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C26H26N2O2
|
2
|
| 1 |
EC50 = 203 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0101898
|
5-chloro-3-(2-isothiocyanatoethyl)-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H27ClN4OS
|
2
|
| 1 |
EC50 = 209 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0955953
|
3-(2-nitro-1-(1H-pyrrol-2-yl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H17N3O2
|
2
|
| 1 |
EC50 = 209 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0396917
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1R,2R,4S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C24H27F2N3O
|
1
|
| 1 |
EC50 = 217 nM
|
|
|
|
CP0951070
|
3-(2-nitro-1-phenylethyl)-2-(1H-pyrrol-2-yl)-1H-indole
Show/Hide
|
C20H17N3O2
|
2
|
| 1 |
EC50 = 220 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0533590
|
7-fluoro-2-(3-fluorophenyl)-3-[1-(4-fluorophenyl)-2-nitroethyl]-1H-indole
Show/Hide
|
C22H15F3N2O2
|
2
|
| 1 |
EC50 = 230 nM
|
|
|
| 2 |
EC50 = 1100 nM
|
|
|
|
CP0003146
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C22H21Cl3N4O
|
11
|
| 1 |
EC50 = 240 nM
|
|
|
| 2 |
IC50 = 2.9 nM
|
|
|
| 3 |
IC50 = 4.5 nM
|
|
|
| 4 |
IC50 = 6.9 nM
|
|
|
| 5 |
IC50 = 120 nM
|
|
|
| 6 |
Ki = 0.19 nM
|
|
|
| 7 |
Ki = 1 nM
|
|
|
| 8 |
Ki = 1.18 nM
|
|
|
| 9 |
Ki = 1.6 nM
|
|
|
| 10 |
Ki = 5.9 nM
|
|
|
| 11 |
Ki = 6.2 nM
|
|
|
|
CP0923270
|
3-(1-(furan-2-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H16N2O3
|
2
|
| 1 |
EC50 = 245 nM
|
|
|
| 2 |
EC50 = 655 nM
|
|
|
|
CP0484158
|
3-(2-nitro-1-pyridin-2-ylethyl)-2-phenyl-1H-indole
Show/Hide
|
C21H17N3O2
|
2
|
| 1 |
EC50 = 260 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0956144
|
2-(1-(6-methyl-2-phenyl-1H-indol-3-yl)-2-nitroethyl)oxazole
Show/Hide
|
C20H17N3O3
|
2
|
| 1 |
EC50 = 261 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0426150
|
7-fluoro-3-[1-(4-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
|
C22H16F2N2O2
|
2
|
| 1 |
EC50 = 270 nM
|
|
|
| 2 |
EC50 = 700 nM
|
|
|
|
CP0459093
|
3-(2-nitro-1-thiophen-2-ylethyl)-2-phenyl-6-(trifluoromethyl)-1H-indole
Show/Hide
|
C21H15F3N2O2S
|
2
|
| 1 |
EC50 = 284 nM
|
|
|
| 2 |
EC50 = 974 nM
|
|
|
|
CP0551008
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-2-fluorobenzenesulfonamide
Show/Hide
|
C28H23Cl2FN6O2S
|
1
|
| 1 |
EC50 = 287.4 nM
|
|
|
|
CP0381508
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopentyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C20H21F2N3O2
|
1
|
| 1 |
EC50 = 297 nM
|
|
|
|
CP0233603
|
N-(1-adamantyl)-1-(2-morpholin-4-ylethyl)indazole-3-carboxamide
Show/Hide
|
C24H32N4O2
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0391365
|
2-cyclopentyl-6-(trifluoromethyl)-3-(3,3,3-trifluoro-1-thiophen-2-ylpropyl)-1H-indole
Show/Hide
|
C21H19F6NS
|
2
|
| 1 |
EC50 = 301 nM
|
|
|
| 2 |
EC50 = 755 nM
|
|
|
|
CP0504362
|
1-(2,4-dichlorophenyl)-5-(5-iodothiophen-2-yl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H19Cl2IN4OS
|
1
|
| 1 |
EC50 = 320 nM
|
|
|
|
CP0518580
|
2-phenyl-6-(trifluoromethyl)-3-(3,3,3-trifluoro-1-thiophen-2-ylpropyl)-1H-indole
Show/Hide
|
C22H15F6NS
|
2
|
| 1 |
EC50 = 322 nM
|
|
|
| 2 |
EC50 = 801 nM
|
|
|
|
CP0379010
|
N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
|
C25H21FN4O2
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0397015
|
(2R,4R)-N-(2-phenylpropan-2-yl)-9-pyridin-3-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H22N4O
|
1
|
| 1 |
EC50 = 341 nM
|
|
|
|
CP0456396
|
(2R,4R)-N-(2-phenylpropan-2-yl)-9-pyridin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H22N4O
|
1
|
| 1 |
EC50 = 381 nM
|
|
|
|
CP0462567
|
5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H19BrCl2N4OS
|
1
|
| 1 |
EC50 = 400 nM
|
|
|
|
CP0957254
|
3-(1-(2-methoxyphenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C23H20N2O3
|
2
|
| 1 |
EC50 = 411 nM
|
|
|
| 2 |
EC50 = 1875 nM
|
|
|
|
CP0926446
|
3-(1-nitro-3-phenylpropan-2-yl)-2-phenyl-1H-indole
Show/Hide
|
C23H20N2O2
|
2
|
| 1 |
EC50 = 420 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0923269
|
3-(2-nitro-1-(3-(pyrrolidin-1-yl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C26H25N3O2
|
2
|
| 1 |
EC50 = 423 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0374913
|
5-methoxy-3-[(3-methoxyphenyl)methyl]-7-pentylchromen-2-one
Show/Hide
|
C23H26O4
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0491409
|
3-[1-(4-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
3
|
| 1 |
EC50 = 440 nM
|
|
|
| 2 |
EC50 = 444 nM
|
|
|
| 3 |
EC50 > 10000 nM
|
|
|
|
CP0490810
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-pyrrolo[2,3-c]pyridine
Show/Hide
|
C21H17N3O2
|
2
|
| 1 |
EC50 = 450 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0393418
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl3N6
|
2
|
| 1 |
EC50 = 462 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0493752
|
6-chloro-3-(2-nitro-1-thiophen-2-ylethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H15ClN2O2S
|
2
|
| 1 |
EC50 = 462 nM
|
|
|
| 2 |
EC50 = 1530 nM
|
|
|
|
CP0955954
|
3-(2-nitro-1-(4-(piperidin-1-yl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C27H27N3O2
|
2
|
| 1 |
EC50 = 476 nM
|
|
|
| 2 |
EC50 = 2460 nM
|
|
|
|
CP0911743
|
3-(1-(naphthalen-2-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C26H20N2O2
|
2
|
| 1 |
EC50 = 483 nM
|
|
|
| 2 |
EC50 = 2344 nM
|
|
|
|
CP0959413
|
3-(1-cyclohexyl-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H24N2O2
|
2
|
| 1 |
EC50 = 495 nM
|
|
|
| 2 |
EC50 = 1897 nM
|
|
|
|
CP0372215
|
5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C21H21BrCl2N4OS
|
1
|
| 1 |
EC50 = 510 nM
|
|
|
|
CP0426149
|
3-(2-nitro-1-pyridin-4-ylethyl)-2-phenyl-1H-indole
Show/Hide
|
C21H17N3O2
|
2
|
| 1 |
EC50 = 510 nM
|
|
|
| 2 |
EC50 = 4000 nM
|
|
|
|
CP0926445
|
3-(1-(furan-3-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H16N2O3
|
2
|
| 1 |
EC50 = 513 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0955955
|
3-(1-(1-methyl-1H-imidazol-2-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H18N4O2
|
2
|
| 1 |
EC50 = 533 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0375422
|
5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C21H21Cl3N4OS
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0960751
|
2-(benzofuran-2-yl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C24H18N2O3
|
2
|
| 1 |
EC50 = 550 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0926444
|
3-(2-nitro-1-(2-(trifluoromethyl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C23H17F3N2O2
|
2
|
| 1 |
EC50 = 557 nM
|
|
|
| 2 |
EC50 = 792 nM
|
|
|
|
CP0437500
|
6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)quinolin-3-amine
Show/Hide
|
C20H15Cl2FN4O
|
1
|
| 1 |
EC50 = 560 nM
|
|
|
|
CP0923266
|
3-(1-(2,6-dichlorophenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C22H16Cl2N2O2
|
2
|
| 1 |
EC50 = 571 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0373856
|
5-(5-Chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H19Cl3N4OS
|
1
|
| 1 |
EC50 = 580 nM
|
|
|
|
CP0955272
|
3-(2-nitro-1-(4-(pyrrolidin-1-yl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C26H25N3O2
|
2
|
| 1 |
EC50 = 618 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0921020
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-(2-morpholinoethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
|
C24H32N4O2
|
1
|
| 1 |
EC50 = 650 nM
|
|
|
|
CP0923267
|
3-(2-nitro-1-(m-tolyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C23H20N2O2
|
2
|
| 1 |
EC50 = 662 nM
|
|
|
| 2 |
EC50 = 1992 nM
|
|
|
|
CP0952515
|
3-(1-(3-methoxyphenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C23H20N2O3
|
2
|
| 1 |
EC50 = 664 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0101895
|
1-(4-benzoylphenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea
Show/Hide
|
C29H26N4O2
|
2
|
| 1 |
EC50 = 683 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0504361
|
5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide
Show/Hide
|
C19H17Cl3N4O2S
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0388674
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-chloroquinolin-3-yl)propanamide
Show/Hide
|
C20H13Cl2FN4O2
|
1
|
| 1 |
EC50 = 710 nM
|
|
|
|
CP0533582
|
2-(2-fluorophenyl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C22H17FN2O2
|
2
|
| 1 |
EC50 = 710 nM
|
|
|
| 2 |
EC50 = 1400 nM
|
|
|
|
CP0022072
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-3-[6-(difluoromethoxy)pyridin-3-yl]urea
Show/Hide
|
C29H24Cl2F2N8O2
|
1
|
| 1 |
EC50 = 718 nM
|
|
|
|
CP0515085
|
3-[1-(3-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
|
C22H17FN2O2
|
4
|
| 1 |
EC50 = 728 nM
|
|
|
| 2 |
EC50 = 730 nM
|
|
|
| 3 |
EC50 = 2500 nM
|
|
|
| 4 |
EC50 > 10000 nM
|
|
|
|
CP0423261
|
N-(1-adamantyl)-1-pentylpyrrolo[2,3-b]pyridine-3-carboxamide
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
|
CP0452689
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-3-(2,4-difluorophenyl)urea
Show/Hide
|
C29H23Cl2F2N7O
|
1
|
| 1 |
EC50 = 765 nM
|
|
|
|
CP0955220
|
2-(3-(2-nitro-1-phenylethyl)-1H-indol-2-yl)thiazole
Show/Hide
|
C19H15N3O2S
|
2
|
| 1 |
EC50 = 790 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0372216
|
5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-N-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-4-methyl-1H-pyrazole-3-carboxamide
Show/Hide
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C22H21Cl3N4OS
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1
|
| 1 |
EC50 = 800 nM
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CP0388581
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N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]-3-(trifluoromethoxy)quinolin-6-amine
Show/Hide
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C21H15ClF4N4O2
|
1
|
| 1 |
EC50 = 850 nM
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CP0914615
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2-(2-nitro-1-(2-phenyl-1H-indol-3-yl)ethyl)oxazole
Show/Hide
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C19H15N3O3
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2
|
| 1 |
EC50 = 856 nM
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| 2 |
EC50 > 10000 nM
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CP0950843
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3-(1-(3-chlorophenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
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C22H17ClN2O2
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2
|
| 1 |
EC50 = 859 nM
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| 2 |
EC50 = 2981 nM
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CP0395175
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N-(2,2-dimethylpropyl)-1-ethyl-4-phenylbenzimidazole-2-carboxamide
Show/Hide
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C21H25N3O
|
1
|
| 1 |
EC50 = 913 nM
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CP0435745
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N-[(2-chlorophenyl)methyl]-1-ethyl-4-phenylbenzimidazole-2-carboxamide
Show/Hide
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C23H20ClN3O
|
1
|
| 1 |
EC50 = 913 nM
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CP0959251
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3-(2-nitro-1-phenylethyl)-2-(1-(triisopropylsilyl)-1H-pyrrol-3-yl)-1H-indole
Show/Hide
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C29H37N3O2Si
|
2
|
| 1 |
EC50 = 970 nM
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| 2 |
EC50 > 10000 nM
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CP0379011
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6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)quinoline
Show/Hide
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C20H14Cl2FN3O2
|
1
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| 1 |
EC50 = 990 nM
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CP0467875
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2-cyclohexyl-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
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C22H24N2O2
|
1
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| 1 |
EC50 = 992 nM
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CP0372217
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5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(pyrrolidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C19H17Cl3N4OS
|
1
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| 1 |
EC50 = 1000 nM
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CP0057171
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3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpiperidin-2-yl)methyl]-1H-indole
Show/Hide
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C22H22IN3O3
|
2
|
| 1 |
EC50 = 1038 nM
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| 2 |
Ki = 2080 nM
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CP0375107
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N-(azepan-1-yl)-5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C21H21Cl3N4OS
|
1
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| 1 |
EC50 = 1100 nM
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CP0434018
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6-fluoro-3-[1-(4-fluorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
Show/Hide
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C22H16F2N2O2
|
2
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| 1 |
EC50 = 1100 nM
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| 2 |
EC50 = 1300 nM
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CP0434019
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3-(2-nitro-1-phenylethyl)-2-pyridin-3-yl-1H-indole
Show/Hide
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C21H17N3O2
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2
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| 1 |
EC50 = 1100 nM
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| 2 |
EC50 > 10000 nM
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CP0437871
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-pyrrolo[2,3-b]pyridine
Show/Hide
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C21H17N3O2
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2
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| 1 |
EC50 = 1100 nM
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| 2 |
EC50 > 10000 nM
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CP0518582
|
3-(6-chloro-2-phenyl-1H-indol-3-yl)-3-phenylpropanenitrile
Show/Hide
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C23H17ClN2
|
2
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| 1 |
EC50 = 1113 nM
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| 2 |
EC50 = 2354 nM
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CP0426031
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6-fluoro-2-(3-fluorophenyl)-3-[1-(4-fluorophenyl)-2-nitroethyl]-1H-indole
Show/Hide
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C22H15F3N2O2
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2
|
| 1 |
EC50 = 1150 nM
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| 2 |
EC50 = 2100 nM
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CP0923268
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3-(1-(4-methoxyphenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
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C23H20N2O3
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2
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| 1 |
EC50 = 1177 nM
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| 2 |
EC50 > 10000 nM
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CP0953052
|
4-(3-(2-nitro-1-phenylethyl)-1H-indol-2-yl)thiazole
Show/Hide
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C19H15N3O2S
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2
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| 1 |
EC50 = 1200 nM
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| 2 |
EC50 > 10000 nM
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CP0529528
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-4-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H20F2N4O
|
1
|
| 1 |
EC50 = 1300 nM
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CP0404193
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1-(4-chlorophenyl)-3-[3-[(6-pyrrolidin-1-ylpyridin-2-yl)amino]phenyl]urea
Show/Hide
|
C22H22ClN5O
|
1
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| 1 |
EC50 = 1300 nM
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CP0952516
|
3-(1-(4-chlorophenyl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
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C22H17ClN2O2
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2
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| 1 |
EC50 = 1315 nM
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| 2 |
EC50 > 10000 nM
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CP0510013
|
1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H20Cl2N4OS
|
1
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| 1 |
EC50 = 1330 nM
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CP0415522
|
2,6-ditert-butyl-4-[2-[4-(dimethylamino)oxan-4-yl]-1,3-oxazol-4-yl]phenol
Show/Hide
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C24H36N2O3
|
2
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| 1 |
EC50 = 1396 nM
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| 2 |
Ki = 817 nM
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CP0923265
|
3-(2-nitro-1-(p-tolyl)ethyl)-2-phenyl-1H-indole
Show/Hide
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C23H20N2O2
|
2
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| 1 |
EC50 = 1444 nM
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| 2 |
EC50 > 10000 nM
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CP0423250
|
2-tert-Butyl-5-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)pyrimidine
Show/Hide
|
C19H20ClFN4O2
|
1
|
| 1 |
EC50 = 1500 nM
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CP0966441
|
5-(3-(2-nitro-1-phenylethyl)-1H-indol-2-yl)thiazole
Show/Hide
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C19H15N3O2S
|
2
|
| 1 |
EC50 = 1500 nM
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| 2 |
EC50 > 10000 nM
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CP0434017
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-pyrrolo[3,2-b]pyridine
Show/Hide
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C21H17N3O2
|
2
|
| 1 |
EC50 = 1600 nM
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| 2 |
EC50 > 10000 nM
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CP0477006
|
3-(2-nitro-1-phenylethyl)-2-pyridin-4-yl-1H-indole
Show/Hide
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C21H17N3O2
|
2
|
| 1 |
EC50 = 1600 nM
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| 2 |
EC50 = 3100 nM
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CP0434026
|
2-(4-fluorophenyl)-3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
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C22H17FN2O2
|
2
|
| 1 |
EC50 = 1600 nM
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| 2 |
EC50 > 10000 nM
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CP0419763
|
N-tert-butyl-4-pyrazin-2-yl-11-oxa-4,5-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-3-carboxamide
Show/Hide
|
C17H21N5O2
|
1
|
| 1 |
EC50 = 1650 nM
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CP0911737
|
3-(2-nitro-1-(2-(pyrrolidin-1-yl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
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C26H25N3O2
|
2
|
| 1 |
EC50 = 1825 nM
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| 2 |
EC50 > 10000 nM
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CP0880786
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-pyrrolo[3,2-c]-pyridine-3-carboxamide
Show/Hide
|
C23H31N3O
|
1
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| 1 |
EC50 = 2100 nM
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CP0504793
|
2,6-ditert-butyl-4-[2-(4-piperidin-1-yloxan-4-yl)-1,3-thiazol-4-yl]phenol
Show/Hide
|
C27H40N2O2S
|
2
|
| 1 |
EC50 = 2256 nM
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| 2 |
Ki = 2173 nM
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CP0412866
|
2,6-ditert-butyl-4-[2-[4-(dimethylamino)thian-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
|
C24H36N2OS2
|
2
|
| 1 |
EC50 = 2376 nM
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| 2 |
Ki = 2343 nM
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CP0401222
|
2,6-ditert-butyl-4-[2-[4-(dimethylamino)oxan-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
|
C24H36N2O2S
|
2
|
| 1 |
EC50 = 2670 nM
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| 2 |
Ki = 857 nM
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CP0547773
|
N-tert-butyl-4-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-4,5-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-3-carboxamide
Show/Hide
|
C17H21N5O3
|
1
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| 1 |
EC50 = 2673 nM
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CP0514913
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N-tert-butyl-4-(2,4-difluorophenyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-5-carboxamide
Show/Hide
|
C19H21F2N3O2
|
1
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| 1 |
EC50 = 2980 nM
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CP0533581
|
3-(2-nitro-1-pyridin-3-ylethyl)-2-phenyl-1H-indole
Show/Hide
|
C21H17N3O2
|
2
|
| 1 |
EC50 = 3100 nM
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| 2 |
EC50 > 10000 nM
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CP0483740
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(2R,4R)-9-(2,4-difluorophenyl)-N-(1-fluoro-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H18F3N3O
|
1
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| 1 |
EC50 = 3400 nM
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CP0400313
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(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyridin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C17H20N4O2
|
1
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| 1 |
EC50 = 3600 nM
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CP0415520
|
2,6-ditert-butyl-4-[2-[4-(diethylamino)oxan-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
|
C26H40N2O2S
|
2
|
| 1 |
EC50 = 4036 nM
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| 2 |
Ki = 3303 nM
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CP0440604
|
3-(2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
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C16H14N2O2
|
1
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| 1 |
EC50 = 5528 nM
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CP0512425
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N-tert-butyl-4-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-5-carboxamide
Show/Hide
|
C17H21N5O3
|
1
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| 1 |
EC50 = 7974 nM
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CP0511698
|
2-(4-chlorophenyl)-N-[3-(3-pyrrolidin-1-ylphenyl)phenyl]acetamide
Show/Hide
|
C24H23ClN2O
|
1
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| 1 |
EC50 > 10000 nM
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CP0391360
|
3-(2-nitro-1-thiophen-2-ylethyl)-2-phenyl-1H-indole-6-carbonitrile
Show/Hide
|
C21H15N3O2S
|
1
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| 1 |
EC50 > 10000 nM
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CP0440605
|
1-methyl-3-(2-nitro-1-phenylethyl)-2-phenylindole
Show/Hide
|
C23H20N2O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0440606
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-pyrrole
Show/Hide
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C18H16N2O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0456939
|
3-(2-nitro-1-phenylethyl)-1H-indole
Show/Hide
|
C16H14N2O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0467874
|
3-(2-nitro-1-phenylethyl)-1-phenylindole
Show/Hide
|
C22H18N2O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0491795
|
2-phenyl-2-(2-phenyl-1H-indol-3-yl)ethanamine
Show/Hide
|
C22H20N2
|
1
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| 1 |
EC50 > 10000 nM
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CP0945731
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-(2-morpholinoethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
Show/Hide
|
C24H32N4O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0946442
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-(5-hydroxypentyl)-1H-benzo[d]imidazole-2-carboxamide
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0493963
|
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-pyrrolo[3,2-c]pyridine
Show/Hide
|
C21H17N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
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CP0911742
|
4-(4-(2-nitro-1-(2-phenyl-1H-indol-3-yl)ethyl)phenyl)morpholine
Show/Hide
|
C26H25N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
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CP0914617
|
3-(1-(naphthalen-1-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C26H20N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
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CP0926443
|
3-(1-(1-methyl-1H-imidazol-5-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H18N4O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0947567
|
3-(1-([1,1'-biphenyl]-4-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C28H22N2O2
|
1
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| 1 |
EC50 > 10000 nM
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CP0947570
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3-(1-(1-methyl-1H-imidazol-4-yl)-2-nitroethyl)-2-phenyl-1H-indole
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
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CP0955663
|
3-(2-nitro-1-(4-(trifluoromethyl)phenyl)ethyl)-2-phenyl-1H-indole
Show/Hide
|
C23H17F3N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
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CP0951067
|
3-(2-nitro-1-phenylethyl)-2-(1H-pyrazol-4-yl)-1H-indole
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0951068
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tert-butyl 3'-(2-nitro-1-phenylethyl)-1H,1'H-2,2'-biindole-1-carboxylate
Show/Hide
|
C29H27N3O4
|
1
|
| 1 |
EC50 > 10000 nM
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CP0960750
|
3-(2-nitro-1-phenylethyl)-2-(1H-pyrazol-3-yl)-1H-indole
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0963909
|
3-(2-nitro-1-phenylethyl)-1H,1'H-2,3'-biindole
Show/Hide
|
C24H19N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0964133
|
3-(2-nitro-1-phenylethyl)-2-(1H-pyrrol-3-yl)-1H-indole
Show/Hide
|
C20H17N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0967942
|
3-(2-nitro-1-phenylethyl)-1H,1'H-2,2'-biindole
Show/Hide
|
C24H19N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0511699
|
1-(4-chlorophenyl)-3-[3-(3-pyrrolidin-1-ylanilino)phenyl]urea
Show/Hide
|
C23H23ClN4O
|
1
|
| 1 |
EC50 = 13500 nM
|
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|
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CP0388262
|
N-(2,2-dimethylpropyl)-4-phenyl-1-(2,2,2-trifluoroethyl)benzimidazole-2-carboxamide
Show/Hide
|
C21H22F3N3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
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CP0388264
|
N-[(2-fluorophenyl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C21H16FN3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
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CP0395176
|
N-[[1-(hydroxymethyl)cyclopentyl]methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0415774
|
N-[(3-fluoropyridin-2-yl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C20H15FN4O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0415775
|
N-benzyl-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C21H17N3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0415776
|
N-[(3-chlorophenyl)methyl]-1-ethyl-4-phenylbenzimidazole-2-carboxamide
Show/Hide
|
C23H20ClN3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0434549
|
N-[[1-(hydroxymethyl)cyclohexyl]methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
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CP0434550
|
1-ethyl-N-[[1-(hydroxymethyl)cyclopentyl]methyl]-4-phenylbenzimidazole-2-carboxamide
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0435746
|
N-[(3-chlorophenyl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C21H16ClN3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0442879
|
N-[1-(hydroxymethyl)cyclohexyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0442887
|
N-[(2-chlorophenyl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C21H16ClN3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
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CP0443542
|
1-ethyl-N-[(2-fluorophenyl)methyl]-4-phenylbenzimidazole-2-carboxamide
Show/Hide
|
C23H20FN3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0443543
|
N-[[1-(hydroxymethyl)cyclohexyl]methyl]-4-phenyl-1-(2,2,2-trifluoroethyl)benzimidazole-2-carboxamide
Show/Hide
|
C24H26F3N3O2
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0443544
|
N-(2,2-dimethylpropyl)-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0443545
|
N-[(4-cyanophenyl)methyl]-1-ethyl-4-phenylbenzimidazole-2-carboxamide
Show/Hide
|
C24H20N4O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0458715
|
1-ethyl-4-phenyl-N-(pyrimidin-5-ylmethyl)benzimidazole-2-carboxamide
Show/Hide
|
C21H19N5O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0481029
|
N-(2,3-dihydroxypropyl)-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0481040
|
4-phenyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1H-benzimidazole-2-carboxamide
Show/Hide
|
C22H16F3N3O
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0484632
|
N-[[1-(hydroxymethyl)cyclopentyl]methyl]-4-phenyl-1-(2,2,2-trifluoroethyl)benzimidazole-2-carboxamide
Show/Hide
|
C23H24F3N3O2
|
1
|
| 1 |
EC50 > 17000 nM
|
|
|
|
CP0875526
|
N-Adamantan-1-yl-1H-indazole-3-carboxamide
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
EC50 = 17100 nM
|
|
|
|
CP0155571
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0375335
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-phenyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0375336
|
(2R,4R)-9-(2,5-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0379951
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(oxan-4-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C19H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0379970
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0381504
|
(2S,4S)-N-tert-butyl-9-(2,4-difluorophenyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0381505
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(oxan-4-ylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C20H21F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0396918
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(oxan-4-ylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C20H21F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0396919
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-3-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H20F2N4O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0396920
|
(2R,4R)-9-(2,6-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0396921
|
(2R,4R)-9-(2-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0397077
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-phenylcyclopropyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H19F2N3O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0397078
|
(2R,4R)-N-tert-butyl-9-(2,4-difluorophenyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0397080
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1S)-2-hydroxy-1-phenylethyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0397081
|
(2S,4S)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H17F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0406642
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrimidin-4-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H19N5O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0410471
|
(2R,4R)-9-(3-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0410473
|
(2R,4R)-9-(4-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0410476
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(oxan-4-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C19H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0410712
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-methyl-1-morpholin-4-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H26F2N4O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0456395
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyridin-3-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0474269
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1R)-2-hydroxy-1-phenylethyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C22H19F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0474274
|
(2R,4R)-9-(2,4-dichlorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19Cl2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0483738
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H17F2N3O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0487953
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrazin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H19N5O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0379008
|
3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)butyl)quinoline
Show/Hide
|
C21H17ClFN3O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0379009
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethyl)pyridin-3-yl)propanamide
Show/Hide
|
C17H11ClF4N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0379012
|
N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]quinolin-6-amine
Show/Hide
|
C20H16ClFN4O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0379014
|
3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(6-chloro-1,8-naphthyridin-3-yl)propanamide
Show/Hide
|
C19H12Cl2FN5O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388568
|
N-(9-ethylcarbazol-3-yl)-3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
|
C25H21FN4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388576
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)propanamide
Show/Hide
|
C19H11ClF4N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388577
|
N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluoro-2-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
|
C26H23FN4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388582
|
5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)isoxazol-3-amine
Show/Hide
|
C18H20ClFN4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388583
|
N-(2-tert-butylpyrimidin-5-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
|
C19H19ClFN5O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388584
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-cyano-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)propanamide
Show/Hide
|
C19H12ClF4N5O3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388585
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(4-(trifluoromethyl)phenyl)propanamide
Show/Hide
|
C18H12ClF4N3O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0388675
|
N-(9-ethylcarbazol-3-yl)-3-[3-(oxan-4-yl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
|
C24H26N4O3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0420845
|
3-(3-(2-Cyano-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide
Show/Hide
|
C26H20FN5O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0423239
|
N-(9-ethylcarbazol-3-yl)-3-[5-(2-fluorophenyl)tetrazol-2-yl]propanamide
Show/Hide
|
C24H21FN6O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0423243
|
5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propylamino)-2-(2,2,2-trifluoroethoxy)nicotinonitrile
Show/Hide
|
C19H14ClF4N5O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0423247
|
3-(3-(3-Cyanopyridin-4-yl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9Hcarbazol-3-yl)propanamide
Show/Hide
|
C25H20N6O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0423248
|
N-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
|
C18H18ClFN4O3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0423249
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide
Show/Hide
|
C25H20ClFN4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0437003
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C18H18ClFN6O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0437503
|
6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)benzo[d]thiazol-2-amine
Show/Hide
|
C18H13Cl2FN4OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0457650
|
3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]propanamide
Show/Hide
|
C18H11Cl2F4N3O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0447674
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-fluorophenyl)-4-hydroxypiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C29H25Cl2FN4O3
|
3
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 0.19 nM
|
|
|
| 3 |
IC50 = 2.6 nM
|
|
|
|
CP0463974
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-cyano-4-phenylpiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C30H25Cl2N5O2
|
3
|
| 1 |
IC50 = 0.11 nM
|
|
|
| 2 |
IC50 = 0.23 nM
|
|
|
| 3 |
IC50 = 0.78 nM
|
|
|
|
CP0498679
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydroxy-4-phenylpiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C29H26Cl2N4O3
|
2
|
| 1 |
IC50 = 0.11 nM
|
|
|
| 2 |
IC50 = 0.26 nM
|
|
|
|
CP0506477
|
2-(3-(5-bromoisoindoline-2-carbonyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C26H17BrCl2N4O
|
1
|
| 1 |
IC50 = 0.22 nM
|
|
|
|
CP0415293
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyrimidin-2-yl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C27H24Cl2N6O2
|
3
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.71 nM
|
|
|
| 3 |
IC50 = 1.4 nM
|
|
|
|
CP0430843
|
4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H24Cl2N6O
|
2
|
| 1 |
IC50 = 0.4 nM
|
|
|
| 2 |
IC50 = 0.93 nM
|
|
|
|
CP0452908
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2,3-dihydro-1H-inden-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C27H20Cl2N4O
|
1
|
| 1 |
IC50 = 0.41 nM
|
|
|
|
CP0452909
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-cycloheptyl-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H24Cl2N4O
|
1
|
| 1 |
IC50 = 0.49 nM
|
|
|
|
CP0463977
|
4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-((1-cyanopiperidin-4-yl)methyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H24Cl2N6O2
|
2
|
| 1 |
IC50 = 0.49 nM
|
|
|
| 2 |
IC50 = 0.66 nM
|
|
|
|
CP0533034
|
N-[(4-bromo-2-fluorophenyl)methyl]-1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H16BrCl2FN4O
|
1
|
| 1 |
IC50 = 0.51 nM
|
|
|
|
CP0523997
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(2-fluorophenyl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C29H25Cl2FN4O2
|
1
|
| 1 |
IC50 = 0.51 nM
|
|
|
|
CP0430989
|
N-(azepan-1-yl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C24H23Cl2N5O
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
|
CP0528548
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(2-fluorophenyl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)-N-hydroxyacetimidamide
Show/Hide
|
C29H26Cl2FN5O2
|
1
|
| 1 |
IC50 = 0.54 nM
|
|
|
|
CP0421778
|
4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-methylpyridin-3-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H19Cl2N5O2
|
3
|
| 1 |
IC50 = 0.55 nM
|
|
|
| 2 |
IC50 = 1.7 nM
|
|
|
| 3 |
IC50 = 3 nM
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CP0498677
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyrimidin-2-yl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetimidamide
Show/Hide
|
C27H25Cl2N7O
|
2
|
| 1 |
IC50 = 0.59 nM
|
|
|
| 2 |
IC50 = 9.7 nM
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CP0499305
|
N-[(3-bromo-4-fluorophenyl)methyl]-1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H16BrCl2FN4O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0492754
|
4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-fluorobenzyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H20Cl2FN5O
|
2
|
| 1 |
IC50 = 0.79 nM
|
|
|
| 2 |
IC50 = 1.2 nM
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CP0421775
|
4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H23Cl2N5O2
|
3
|
| 1 |
IC50 = 0.82 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
| 3 |
IC50 = 1.8 nM
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CP0400411
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-fluorophenyl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C29H23Cl2FN4O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0538649
|
N-[[4-(4-fluorophenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H17FN2O2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0533978
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-fluorophenyl)-4-(2-(hydroxyamino)-2-iminoethyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H18Cl2FN5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
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CP0430864
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H17Cl3N4O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0533031
|
methyl 2-[[1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carbonyl]amino]-3-phenylpropanoate
Show/Hide
|
C28H22Cl2N4O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0452250
|
N-[(4-bromophenyl)methyl]-1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H17BrCl2N4O
|
2
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 5.8 nM
|
|
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CP0447709
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(5-cyanopyridin-2-yl)piperazine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C28H23Cl2N7O2
|
3
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
| 3 |
IC50 = 4.6 nM
|
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CP0401973
|
4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(1-(cyclopropanecarbonyl)piperidin-4-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C27H27Cl2N5O3
|
2
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 3.7 nM
|
|
|
|
CP0219312
|
US9266835, 44
Show/Hide
|
C28H24Cl2F3N3O3S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0447708
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(2-(hydroxyamino)-2-iminoethyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H24Cl2N6O2
|
2
|
| 1 |
IC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 1.8 nM
|
|
|
|
CP0447671
|
4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H18Cl2FN5O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0439037
|
CHEMBL599964
Show/Hide
|
C25H24Cl2N4O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0535551
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2,4-dichlorobenzyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H16Cl4N4O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0499304
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-((1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C27H20Cl2N4O2
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0373536
|
4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-morpholino-1H-pyrazole-3-carboxamide
Show/Hide
|
C22H21Cl2N5O3
|
3
|
| 1 |
IC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
| 3 |
IC50 = 7.9 nM
|
|
|
|
CP0417930
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H21Cl2N5O
|
2
|
| 1 |
IC50 = 1.8 nM
|
|
|
| 2 |
IC50 = 7.5 nM
|
|
|
|
CP0535549
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-cyclohexyl-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H22Cl2N4O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0533977
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-fluorophenyl)-4-hydroxypiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetimidamide
Show/Hide
|
C29H26Cl2FN5O2
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0447672
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-hydroxy-4-(pyridin-2-yl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C28H25Cl2N5O3
|
3
|
| 1 |
IC50 = 1.9 nM
|
|
|
| 2 |
IC50 = 2 nM
|
|
|
| 3 |
IC50 = 3.6 nM
|
|
|
|
CP0538648
|
N-[[4-(4-methoxyphenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H20N2O3S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0538650
|
N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H18N2O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0430990
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(4-fluorobenzyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H17Cl2FN4O
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0513980
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C28H19Cl2F3N4O
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0463975
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(5-fluoropyridin-2-yl)-4-hydroxypiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C28H24Cl2FN5O3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0490983
|
N-[(1R,2R,4S)-2-bicyclo[2.2.1]heptanyl]-1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H22Cl2N4O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0513982
|
methyl 2-[1-[1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carbonyl]piperidin-4-yl]benzoate
Show/Hide
|
C31H26Cl2N4O3
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0506467
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-[(3-chlorophenyl)methyl]-4-(cyanomethyl)pyrazole-3-carboxamide
Show/Hide
|
C25H17Cl3N4O
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0510371
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(4-fluorophenyl)-4-hydroxypiperidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C29H23Cl2FN4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0488197
|
N-[[4-(4-methylphenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0488198
|
N-[[4-[4-(dimethylamino)phenyl]phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C23H23N3O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0537568
|
N-[[4-(6-fluoropyridin-3-yl)phenyl]methyl]-5-methoxy-1H-indole-2-sulfonamide
Show/Hide
|
C21H18FN3O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0549726
|
5-chloro-N-[[5-(2,4-difluorophenyl)pyridin-2-yl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C20H14ClF2N3O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0506225
|
2-(3-(4-benzyl-4-hydroxypiperidine-1-carbonyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C30H26Cl2N4O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0471588
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C26H21Cl2N7O
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0401968
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyrimidin-2-yl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C27H22Cl2N6O
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0480256
|
5-chloro-N-[[4-(2,4-difluorophenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H15ClF2N2O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0488202
|
5-bromo-N-[[5-(2,4-difluorophenyl)pyridin-2-yl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C20H14BrF2N3O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0537569
|
5-chloro-N-[[4-(2,6-difluoropyridin-3-yl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C20H14ClF2N3O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0538647
|
6-chloro-N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H17ClN2O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0504589
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2-fluorobenzyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H17Cl2FN4O
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0494748
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-cyanobenzyl)-4-(cyanomethyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C26H17Cl2N5O
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0803531
|
US9266835, 41
Show/Hide
|
C25H22ClF3N4O3S2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0480260
|
6-fluoro-N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H17FN2O2S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0538659
|
6-chloro-N-[[4-(6-fluoropyridin-3-yl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C20H15ClFN3O2S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0541949
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(4-fluorobenzyl)-N-methyl-1H-pyrazole-3-carboxamide
Show/Hide
|
C26H19Cl2FN4O
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0439038
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(5-fluoroisoindoline-2-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C26H17Cl2FN4O
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0506466
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C27H20Cl2N4O
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0533030
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(pentan-3-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H22Cl2N4O
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0488196
|
5-bromo-N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H17BrN2O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0496148
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2,6-dichlorobenzyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H16Cl4N4O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0574930
|
N-[(4-pyridin-3-ylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C20H17N3O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0544210
|
methyl 2-[[1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)pyrazole-3-carbonyl]amino]-3-methylbutanoate
Show/Hide
|
C24H22Cl2N4O3
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0506475
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C27H20Cl2N4O2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0551479
|
N-[[4-(4-cyanophenyl)phenyl]methyl]-5-methoxy-1H-indole-2-sulfonamide
Show/Hide
|
C23H19N3O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0561564
|
3-methyl-N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0554572
|
5-bromo-N-[[5-(4-fluorophenyl)pyridin-2-yl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C20H15BrFN3O2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0504730
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(3-(4-fluorophenyl)pyrrolidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C28H21Cl2FN4O
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0911978
|
5-(2-chloro-5-(trifluoromethyl)phenyl)-1-(cyclohexylmethyl)-N-((1R,2R)-2-hydroxycyclohexyl)-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C26H32ClF3N2O2
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0421779
|
1-(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carbonyl)-4-(pyridin-2-yl)piperidine-4-carboxylic acid
Show/Hide
|
C29H25Cl2N5O4
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
| 3 |
IC50 = 23 nM
|
|
|
|
CP0491187
|
3-(methoxymethyl)-N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C23H22N2O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0551490
|
N-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H21N3O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0383853
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H15Cl2FN4O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0491188
|
3-(hydroxymethyl)-N-[(4-phenylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H20N2O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0537564
|
5-bromo-N-[[4-(4-fluorophenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H16BrFN2O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0538658
|
N-[(4-thiophen-3-ylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C19H16N2O2S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0506483
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-phenylpiperazine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
|
C28H23Cl2N5O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0471585
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(6-(trifluoromethyl)pyridin-3-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H14Cl2F3N5O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0506223
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-((5-methylisoxazol-3-yl)methyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H17Cl2N5O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0482960
|
5-chloro-N-[[4-(4-methylsulfonylphenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H19ClN2O4S2
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1
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| 1 |
IC50 = 15 nM
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CP0531007
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N-[[4-(4-methylsulfonylphenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
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C22H20N2O4S2
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1
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| 1 |
IC50 = 15 nM
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CP0499303
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-phenethyl-1H-pyrazole-3-carboxamide
Show/Hide
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C26H20Cl2N4O
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1
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| 1 |
IC50 = 16 nM
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CP0533033
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2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(methylsulfonyl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
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C24H22Cl2N4O3S
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1
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| 1 |
IC50 = 17 nM
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CP0536625
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(2-chloropyridin-3-yl)-4-(cyanomethyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C23H14Cl3N5O
|
1
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| 1 |
IC50 = 18 nM
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CP0533029
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(quinolin-3-yl)-1H-pyrazole-3-carboxamide
Show/Hide
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C27H17Cl2N5O
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1
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| 1 |
IC50 = 19 nM
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CP0533032
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2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-((R)-3-(4-fluorobenzyloxy)pyrrolidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
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C29H23Cl2FN4O2
|
1
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| 1 |
IC50 = 20 nM
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CP0528549
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2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(4-(pyrimidin-2-yl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)-N-hydroxyacetimidamide
Show/Hide
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C27H25Cl2N7O2
|
1
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| 1 |
IC50 = 21 nM
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CP0537566
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5-chloro-N-[[2-fluoro-4-(4-fluorophenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
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C21H15ClF2N2O2S
|
1
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| 1 |
IC50 = 21 nM
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CP0557462
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N-[[4-(2,4-dimethoxyphenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
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C23H22N2O4S
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1
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| 1 |
IC50 = 22 nM
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CP0536627
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2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(2-(4-fluorophenyl)piperidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
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C29H23Cl2FN4O
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1
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| 1 |
IC50 = 23 nM
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CP0510370
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4-(2-amino-2-iminoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-morpholino-1H-pyrazole-3-carboxamide
Show/Hide
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C22H22Cl2N6O2
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1
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| 1 |
IC50 = 26 nM
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CP0513981
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2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(2-(4-fluorophenyl)pyrrolidine-1-carbonyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
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C28H21Cl2FN4O
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1
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| 1 |
IC50 = 27 nM
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CP0463976
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1-(4-(2-amino-2-oxoethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carbonyl)-4-(5-fluoropyridin-2-yl)piperidine-4-carboxylic acid
Show/Hide
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C29H24Cl2FN5O4
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1
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| 1 |
IC50 = 30 nM
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CP0452910
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazole-3-carboxamide
Show/Hide
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C24H23Cl2N5O3S
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1
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| 1 |
IC50 = 31 nM
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CP0561562
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N-[[4-(4-hydroxy-3-methoxyphenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
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C22H20N2O4S
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1
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| 1 |
IC50 = 33 nM
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CP0537567
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N-[[2-fluoro-4-[4-(trifluoromethoxy)phenyl]phenyl]methyl]-5-methoxy-1H-indole-2-sulfonamide
Show/Hide
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C23H18F4N2O4S
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1
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| 1 |
IC50 = 40 nM
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CP0538660
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N-[1-[4-(4-fluorophenyl)phenyl]ethyl]-1H-indole-2-sulfonamide
Show/Hide
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C22H19FN2O2S
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1
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| 1 |
IC50 = 41 nM
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CP0459966
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4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
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C25H31BrClN3O
|
1
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| 1 |
IC50 = 49.4 nM
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CP0523996
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(2-(hydroxyamino)-2-iminoethyl)-N-morpholino-1H-pyrazole-3-carboxamide
Show/Hide
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C22H22Cl2N6O3
|
1
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| 1 |
IC50 = 51 nM
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CP0514585
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(4-(cyanomethyl)phenyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C26H17Cl2N5O
|
1
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| 1 |
IC50 = 55 nM
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CP0541948
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
Show/Hide
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C23H15Cl2N5O
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1
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| 1 |
IC50 = 57 nM
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CP0528485
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4-((4-Bromophenyl)(2-chlorophenyl)methyl)-Ncyclohexylpiperazine-1-carboxamide
Show/Hide
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C24H29BrClN3O
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1
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| 1 |
IC50 = 62.8 nM
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CP0486873
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3-((4,4-difluoropiperidin-1-yl)methyl)-N-((1-(hydroxymethyl)cyclopentyl)methyl)imidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
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C21H28F2N4O2
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1
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| 1 |
IC50 = 68 nM
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CP0430988
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-morpholino-1H-pyrazole-3-carboxamide
Show/Hide
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C22H19Cl2N5O2
|
1
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| 1 |
IC50 = 71 nM
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CP0571864
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N-[[4-(6-aminopyridin-3-yl)phenyl]methyl]-5-chloro-1H-indole-2-sulfonamide
Show/Hide
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C20H17ClN4O2S
|
1
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| 1 |
IC50 = 85 nM
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CP0456333
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(2,3-dichlorophenyl)(1-((4,4-difluoropiperidin-1-yl)methyl)imidazo[1,5-a]pyridin-3-yl)methanone
Show/Hide
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C20H17Cl2F2N3O
|
1
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| 1 |
IC50 = 90 nM
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CP0480257
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N-[[4-[4-(hydroxymethyl)phenyl]phenyl]methyl]-5-methoxy-1H-indole-2-sulfonamide
Show/Hide
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C23H22N2O4S
|
1
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| 1 |
IC50 = 112 nM
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CP0578890
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5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-sulfonamide
Show/Hide
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C23H28ClN3O2S
|
1
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| 1 |
IC50 = 120 nM
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CP0484630
|
4-((2-Chlorophenyl)(4-chlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C24H29Cl2N3O
|
1
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| 1 |
IC50 = 128 nM
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CP0537565
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5-chloro-N-[2-[4-(dimethylamino)phenyl]ethyl]-3-ethyl-1H-indole-2-sulfonamide
Show/Hide
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C20H24ClN3O2S
|
1
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| 1 |
IC50 = 130 nM
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CP0578891
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N-[[3-(4-fluorophenyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
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C21H17FN2O2S
|
1
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| 1 |
IC50 = 137 nM
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CP0372423
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4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
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C25H31BrClN3O
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1
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| 1 |
IC50 = 146 nM
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CP0491312
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4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
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C26H34ClN3O
|
1
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| 1 |
IC50 = 163 nM
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CP0459967
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4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C25H29ClF3N3O
|
1
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| 1 |
IC50 = 186 nM
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CP0473967
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-2-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
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| 1 |
IC50 = 188 nM
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CP0372425
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4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C25H32ClN3O
|
1
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| 1 |
IC50 = 195 nM
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CP0494747
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2-(3-(4-acetylpiperidine-1-carbonyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazol-4-yl)acetonitrile
Show/Hide
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C25H22Cl2N4O2
|
1
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| 1 |
IC50 = 199 nM
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CP0491186
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N-[(4-methoxyphenyl)methyl]-3-methyl-1H-indole-2-sulfonamide
Show/Hide
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C17H18N2O3S
|
1
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| 1 |
IC50 = 200 nM
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CP0561566
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N-[(4-methoxyphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
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C16H16N2O3S
|
1
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| 1 |
IC50 = 200 nM
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CP0571933
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3-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-sulfonamide
Show/Hide
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C22H27N3O2S
|
1
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| 1 |
IC50 = 200 nM
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CP0578889
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3-methyl-N-[(4-methylphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
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C17H18N2O2S
|
1
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| 1 |
IC50 = 200 nM
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CP0401169
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4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
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C26H31ClF3N3O
|
1
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| 1 |
IC50 = 204 nM
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CP0372422
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4-((2-Chlorophenyl)(4-chlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
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C25H31Cl2N3O
|
1
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| 1 |
IC50 = 226 nM
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CP0561565
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3-methyl-N-[[4-(trifluoromethyl)phenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
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C17H15F3N2O2S
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1
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| 1 |
IC50 = 250 nM
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CP0478652
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[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-6-ylmethanone
Show/Hide
|
C25H26N2O2
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1
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| 1 |
IC50 = 261 nM
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CP0458884
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4-((2-Chlorophenyl)(4-chlorophenyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
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C25H31Cl2N3O
|
1
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| 1 |
IC50 = 273 nM
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CP0379057
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4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-tert-butylpiperazine-1-carboxamide
Show/Hide
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C22H27BrClN3O
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1
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| 1 |
IC50 = 286 nM
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CP0480259
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3-[4-[(1H-indol-2-ylsulfonylamino)methyl]phenyl]benzamide
Show/Hide
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C22H19N3O3S
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1
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| 1 |
IC50 = 300 nM
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CP0538657
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N-[2-[4-(dimethylamino)phenyl]ethyl]-3-methyl-1H-indole-2-sulfonamide
Show/Hide
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C19H23N3O2S
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1
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| 1 |
IC50 = 300 nM
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CP0438981
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[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(4-chlorophenyl)methanone
Show/Hide
|
C22H24ClNO2
|
1
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| 1 |
IC50 = 312 nM
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CP0535141
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N-tert-butyl-4-[(4-chlorophenyl)-(2,3-dichlorophenyl)methyl]piperazine-1-carboxamide
Show/Hide
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C22H26Cl3N3O
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1
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| 1 |
IC50 = 316 nM
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CP0372424
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N-tert-butyl-4-[(4-chlorophenyl)-(2-methylphenyl)methyl]piperazine-1-carboxamide
Show/Hide
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C23H30ClN3O
|
1
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| 1 |
IC50 = 334 nM
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CP0398998
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4-((4-Chlorophenyl)(o-tolyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
|
C26H34ClN3O
|
1
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| 1 |
IC50 = 340 nM
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CP0422123
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1-((4,4-difluoropiperidin-1-yl)methyl)-N-(6-(trifluoromethyl)pyridin-2-yl)imidazo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C20H18F5N5O
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1
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| 1 |
IC50 = 347 nM
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CP0399000
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4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C24H28Cl3N3O
|
1
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| 1 |
IC50 = 367 nM
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CP0866740
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5-[2-Chloro-5-(trifluoromethyl)phenyl]-6-(cyclopentyloxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C24H26ClF3N2O3
|
1
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| 1 |
IC50 = 395 nM
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CP0538656
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5-methoxy-N-[(4-methoxyphenyl)methyl]-1H-indole-2-sulfonamide
Show/Hide
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C17H18N2O4S
|
1
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| 1 |
IC50 = 400 nM
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CP0577969
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N-[(4-chlorophenyl)methyl]-3-methyl-1H-indole-2-sulfonamide
Show/Hide
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C16H15ClN2O2S
|
1
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| 1 |
IC50 = 400 nM
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CP0399001
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4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C25H30Cl3N3O
|
1
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| 1 |
IC50 = 424 nM
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CP0379058
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4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C24H28Cl3N3O
|
1
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| 1 |
IC50 = 441 nM
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CP0398999
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N-tert-butyl-4-[(2-chlorophenyl)-(4-chlorophenyl)methyl]piperazine-1-carboxamide
Show/Hide
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C22H27Cl2N3O
|
1
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| 1 |
IC50 = 443 nM
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CP0538655
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5-chloro-N-[(4-methoxyphenyl)methyl]-3-methyl-1H-indole-2-sulfonamide
Show/Hide
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C17H17ClN2O3S
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1
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| 1 |
IC50 = 500 nM
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CP0575969
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5-chloro-3-ethyl-N-[2-(4-morpholin-4-ylphenyl)ethyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H26ClN3O3S
|
1
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| 1 |
IC50 = 500 nM
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CP0465939
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(R)-3-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-yl)ethyl)imidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C19H18F3N5O2
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1
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| 1 |
IC50 = 705 nM
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CP0566990
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4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C25H30Cl3N3O
|
1
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| 1 |
IC50 = 729 nM
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CP0459965
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4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
|
C26H31ClF3N3O
|
1
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| 1 |
IC50 = 798 nM
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CP0488199
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N-[(3,4-dichlorophenyl)methyl]-3-methyl-1H-indole-2-sulfonamide
Show/Hide
|
C16H14Cl2N2O2S
|
1
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| 1 |
IC50 = 800 nM
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CP0488200
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N-[(3-chlorophenyl)methyl]-3-methyl-1H-indole-2-sulfonamide
Show/Hide
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C16H15ClN2O2S
|
1
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| 1 |
IC50 = 800 nM
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CP0494384
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[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(4-chlorophenyl)methanone
Show/Hide
|
C22H24ClNO2
|
1
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| 1 |
IC50 = 963 nM
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CP0442074
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[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indol-5-yl)methanone
Show/Hide
|
C24H26N2O2
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1
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| 1 |
IC50 = 1002 nM
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CP0401145
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4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
|
C25H30Cl3N3O
|
1
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| 1 |
IC50 = 1040 nM
|
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CP0494746
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2-(piperidin-1-yl)ethyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C25H25Cl2N5O
|
1
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| 1 |
IC50 = 1110 nM
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CP0442065
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[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-3-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
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| 1 |
IC50 = 1528 nM
|
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CP0473965
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[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-2-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
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| 1 |
IC50 = 2022 nM
|
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CP0456331
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(3-fluoro-2-(trifluoromethyl)phenyl)(1-(morpholinomethyl)imidazo[1,5-a]pyridin-3-yl)methanone
Show/Hide
|
C20H17F4N3O2
|
1
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| 1 |
IC50 = 2229 nM
|
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CP0456330
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(2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1,5-a]pyridin-3-yl)methanone
Show/Hide
|
C19H17Cl2N3O2
|
1
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| 1 |
IC50 = 2565 nM
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CP0475140
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2-(1-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-1H-pyrazole-3-carbonyl)piperidin-4-yl)benzoic acid
Show/Hide
|
C30H24Cl2N4O3
|
1
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| 1 |
IC50 = 2810 nM
|
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CP0510176
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,6-naphthyridin-2-yl)methanone
Show/Hide
|
C24H25N3O2
|
1
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| 1 |
IC50 = 3441 nM
|
|
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CP0478657
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[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,3-oxazol-5-yl)methanone
Show/Hide
|
C19H22N2O3
|
1
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| 1 |
IC50 = 3445 nM
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CP0396093
|
N-(1-adamantyl)-1-[hydroxy(pyridin-3-yl)methyl]imidazo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
IC50 = 3881 nM
|
|
|
|
CP0436297
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[4-(2,2,2-trifluoroethyl)morpholin-2-yl]methanone
Show/Hide
|
C22H29F3N2O3
|
1
|
| 1 |
IC50 = 4044 nM
|
|
|
|
CP0506224
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-1H-pyrazole-3-carboxamido)-3-phenylpropanoic acid
Show/Hide
|
C27H20Cl2N4O3
|
1
|
| 1 |
IC50 = 4450 nM
|
|
|
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CP0438979
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
IC50 = 4543 nM
|
|
|
|
CP0417932
|
2-(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-1H-pyrazole-3-carboxamido)-3-methylbutanoic acid
Show/Hide
|
C23H20Cl2N4O3
|
1
|
| 1 |
IC50 = 6250 nM
|
|
|
|
CP0482152
|
1-[(1,1-dioxidothiomorpholin-4-yl)methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]imidazo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C19H18F3N5O3S
|
1
|
| 1 |
IC50 = 12700 nM
|
|
|
|
CP0422830
|
1-(3,3-difluoropyrrolidin-1-yl)-N-((4-fluorophenyl)(pyridin-4-yl)methyl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C23H19F3N6O
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0436035
|
N-[[1-(hydroxymethyl)cyclopentyl]methyl]-3-morpholin-4-ylimidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C19H26N4O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0456332
|
3-cyclopropyl-N-neopentylimidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
IC50 > 17000 nM
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|
|
|
CP0467664
|
(R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-yl)ethyl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C18H17F3N6O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0467665
|
1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-3-yl)ethyl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C18H17F3N6O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0486872
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(R)-1-(4,4-difluoropiperidin-1-yl)-N-(3,3-dimethylbutan-2-yl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C18H25F2N5O
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0494387
|
3-cyclopropyl-N-(dicyclopropylmethyl)imidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0436295
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylimidazol-2-yl)methanone
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0436298
|
((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)((S)-4-methylmorpholin-3-yl)methanone
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0438982
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(6-methylpyridin-2-yl)methanone
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0438986
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[6-(trifluoromethyl)pyridin-3-yl]methanone
Show/Hide
|
C22H23F3N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0442067
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-benzimidazol-4-yl)methanone
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0442069
|
4-[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinoline-1-carbonyl]pyrrolidin-2-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0442076
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indazol-4-yl)methanone
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0442078
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(3-fluoropyridin-4-yl)methanone
Show/Hide
|
C21H23FN2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0460404
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,2-oxazol-3-yl)methanone
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0460407
|
5-[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinoline-1-carbonyl]pyrrolidin-2-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0462994
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpiperidin-2-yl)methanone
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0465453
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpiperidin-4-yl)methanone
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0465454
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[3-(2-fluorophenyl)-1H-pyrazol-5-yl]methanone
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0465455
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpyrrolidin-3-yl)methanone
Show/Hide
|
C21H30N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0465459
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indol-4-yl)methanone
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0473916
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]methanone
Show/Hide
|
C23H25F3N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0473931
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(6-cyclopropylpyridin-3-yl)methanone
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0473933
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-1,2,4-triazol-5-yl)methanone
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0473934
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[(2S,4S)-4-hydroxypiperidin-2-yl]methanone
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0478648
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(4-methylmorpholin-3-yl)methanone
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0478651
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0478744
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indol-4-yl)methanone
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0491382
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,3-thiazol-4-yl)methanone
Show/Hide
|
C19H22N2O2S
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0491383
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0491384
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]methanone
Show/Hide
|
C21H24F3N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0494383
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-pyrimidin-2-ylmethanone
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0494385
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpyrrolidin-3-yl)methanone
Show/Hide
|
C21H30N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0494386
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-piperazin-2-ylmethanone
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0504979
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[3-(2-fluorophenyl)-1H-pyrazol-5-yl]methanone
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0507677
|
5-[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinoline-1-carbonyl]-1-methylpiperidin-2-one
Show/Hide
|
C22H30N2O3
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0482962
|
3-methyl-N-(2-phenylethyl)-1H-indole-2-sulfonamide
Show/Hide
|
C17H18N2O2S
|
1
|
| 1 |
IC50 > 200 nM
|
|
|
|
CP0482941
|
3-methyl-N-[2-(4-morpholin-4-ylphenyl)ethyl]-1H-indole-2-sulfonamide
Show/Hide
|
C21H25N3O3S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0484589
|
3-methyl-N-(3-morpholin-4-ylpropyl)-1H-indole-2-sulfonamide
Show/Hide
|
C16H23N3O3S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0488201
|
N-benzyl-3-methyl-1H-indole-2-sulfonamide
Show/Hide
|
C16H16N2O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0538651
|
3-methyl-N-(2-morpholin-4-ylethyl)-1H-indole-2-sulfonamide
Show/Hide
|
C15H21N3O3S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0538652
|
3-methyl-N-(pyridin-3-ylmethyl)-1H-indole-2-sulfonamide
Show/Hide
|
C15H15N3O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0538653
|
3-methyl-N-(pyridin-2-ylmethyl)-1H-indole-2-sulfonamide
Show/Hide
|
C15H15N3O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0538654
|
5-chloro-N-[(4-chlorophenyl)methyl]-3-ethyl-1H-indole-2-sulfonamide
Show/Hide
|
C17H16Cl2N2O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0558172
|
5-chloro-N-[[4-(4-fluorophenyl)-2-methylphenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H18ClFN2O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0561563
|
4-[4-[(1H-indol-2-ylsulfonylamino)methyl]phenyl]benzoic acid
Show/Hide
|
C22H18N2O4S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0561567
|
5-chloro-N-[[4-(4-fluorophenyl)-3-methylphenyl]methyl]-1H-indole-2-sulfonamide
Show/Hide
|
C22H18ClFN2O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0565001
|
N-(cyclohexylmethyl)-3-methyl-1H-indole-2-sulfonamide
Show/Hide
|
C16H22N2O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0432518
|
N-[(8R)-2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methylpropanamide
Show/Hide
|
C23H23Cl2N3O2
|
1
|
| 1 |
Ki = 0.03 nM
|
|
|
|
CP0895933
|
(R,S)-N-[2-(2-Chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydro-2H-oxepino[3,2-c]pyrazol-8-yl]-2-methylpropanamide
Show/Hide
|
C23H23Cl2N3O2
|
1
|
| 1 |
Ki = 0.04 nM
|
|
|
|
CP0475994
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]cyclohexanecarboxamide
Show/Hide
|
C26H27Cl2N3O2
|
1
|
| 1 |
Ki = 0.05 nM
|
|
|
|
CP0434132
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]oxane-4-carboxamide
Show/Hide
|
C25H25Cl2N3O3
|
1
|
| 1 |
Ki = 0.07 nM
|
|
|
|
CP0443609
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1,2,5-oxadiazole-3-carboxamide
Show/Hide
|
C22H17Cl2N5O3
|
1
|
| 1 |
Ki = 0.08 nM
|
|
|
|
CP0509763
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1-cyanocyclopropane-1-carboxamide
Show/Hide
|
C24H20Cl2N4O2
|
1
|
| 1 |
Ki = 0.08 nM
|
|
|
|
CP0442489
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-difluoropropyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C20H14Cl2F2N4O
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0457027
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H11Cl2F3N4O
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0375597
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-3-(1-(2-phenylpropan-2-yl)-1H-imidazol-4-yl)-1H-pyrazole
Show/Hide
|
C28H23Cl3N4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0500614
|
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(1-(2-phenylpropan-2-yl)-1H-imidazol-4-yl)-1H-pyrazole
Show/Hide
|
C28H24Cl2N4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0441039
|
1-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-3-ethylurea
Show/Hide
|
C22H22Cl2N4O2
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0462175
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]propanamide
Show/Hide
|
C22H21Cl2N3O2
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0295447
|
1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide
Show/Hide
|
C25H25Cl2N7O
|
2
|
| 1 |
Ki = 0.12 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0425911
|
propan-2-yl N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]carbamate
Show/Hide
|
C23H23Cl2N3O3
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0467377
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1,2-oxazole-5-carboxamide
Show/Hide
|
C23H18Cl2N4O3
|
1
|
| 1 |
Ki = 0.23 nM
|
|
|
|
CP0420951
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C23H18Cl2N4O3
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1
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| 1 |
Ki = 0.26 nM
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CP0466917
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US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexane-1-carboxamide
Show/Hide
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C30H25Cl2N5O
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2
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| 1 |
Ki = 0.28 nM
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| 2 |
Ki = 1.79 nM
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CP0428016
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1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidine-4-carboxamide
Show/Hide
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C29H25Cl3N4O2
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3
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| 1 |
Ki = 0.4 nM
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| 2 |
Ki = 3.4 nM
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| 3 |
Ki = 3.44 nM
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CP0035700
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ether-based lactam, 19e
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C22H19Cl2F2N3O2
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1
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| 1 |
Ki = 0.7 nM
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CP0409089
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methyl N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]carbamate
Show/Hide
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C21H19Cl2N3O3
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1
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| 1 |
Ki = 0.72 nM
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CP0307468
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lactam-based compound, 12i
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C21H17Cl2F2N3O
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1
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| 1 |
Ki = 0.8 nM
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CP0037081
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PF-514273
Show/Hide
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C21H17Cl2F2N3O2
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1
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| 1 |
Ki = 0.82 nM
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CP0409567
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N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methylsulfonylacetamide
Show/Hide
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C22H21Cl2N3O4S
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1
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| 1 |
Ki = 0.82 nM
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CP0439886
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N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]acetamide
Show/Hide
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C21H19Cl2N3O2
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1
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| 1 |
Ki = 0.87 nM
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CP0542768
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(3-chlorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
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C28H23Cl3N6
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1
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| 1 |
Ki = 0.9 nM
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CP0136518
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-methyl-6-(2,2,2-trifluoroethyl)pyrazolo[4,3-d]pyrimidin-7-one
Show/Hide
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C20H13Cl2F3N4O
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1
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| 1 |
Ki = 1 nM
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CP0401262
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[3,4-c]pyridin-7(6H)-one
Show/Hide
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C20H12Cl2F3N3O
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1
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| 1 |
Ki = 1 nM
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CP0435518
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-difluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C19H12Cl2F2N4O
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1
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| 1 |
Ki = 1 nM
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CP0859347
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-1-(2,2,2-trifluoroethyl)-4,9-dihydro-1H-purin-6(5H)-one
Show/Hide
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C19H13Cl2F3N4O
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1
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| 1 |
Ki = 1 nM
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CP0489825
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
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C28H23Cl3N6
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1
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| 1 |
Ki = 1 nM
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CP0289084
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(piperidin-1-yl)-9H-purine
Show/Hide
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C22H19Cl2N5
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1
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| 1 |
Ki = 1.1 nM
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CP0412606
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(1-phenylethyl)piperazin-1-yl]purine
Show/Hide
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C29H26Cl2N6
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1
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| 1 |
Ki = 1.1 nM
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CP0489872
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N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-ethoxyacetamide
Show/Hide
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C23H23Cl2N3O3
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1
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| 1 |
Ki = 1.2 nM
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CP0428014
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N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]benzenesulfonamide
Show/Hide
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C28H24Cl2N6O2S
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1
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| 1 |
Ki = 1.2 nM
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CP0035697
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ether-based lactam, 19c
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C20H14Cl2F3N3O2
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1
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| 1 |
Ki = 1.5 nM
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CP0339943
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9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(4-methylpiperazin-1-yl)-9H-purine
Show/Hide
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C22H19Cl3N6
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1
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| 1 |
Ki = 1.5 nM
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CP0341653
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9-(4-chlorophenyl)-N-cyclohexyl-8-(2,4-dichlorophenyl)-9H-purin-6-amine
Show/Hide
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C23H20Cl3N5
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1
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| 1 |
Ki = 1.5 nM
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CP0540679
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tert-butyl N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]carbamate
Show/Hide
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C27H28Cl2N6O2
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1
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| 1 |
Ki = 1.5 nM
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CP0385624
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}cyclopentanecarboxamide
Show/Hide
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C28H28Cl2N6O
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1
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| 1 |
Ki = 1.54 nM
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CP0109122
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-9H-purine
Show/Hide
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C22H20Cl2N6
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2
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| 1 |
Ki = 1.6 nM
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| 2 |
Ki = 3 nM
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CP0090273
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9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-9H-purin-6-amine
Show/Hide
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C22H19Cl3N6
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1
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| 1 |
Ki = 1.7 nM
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CP0291135
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9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(piperidin-1-yl)-9H-purine
Show/Hide
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C22H18Cl3N5
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1
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| 1 |
Ki = 1.7 nM
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CP0499944
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1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidine-4-carboxamide
Show/Hide
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C29H24Cl2N6O
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1
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| 1 |
Ki = 1.79 nM
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CP0399454
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-2-cyclohexylacetamide
Show/Hide
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C30H32Cl2N6O
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1
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| 1 |
Ki = 1.93 nM
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CP0371734
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C20H16Cl2N4O
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1
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| 1 |
Ki = 2 nM
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CP0416809
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(2-phenylethyl)piperazin-1-yl]purine
Show/Hide
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C29H26Cl2N6
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1
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| 1 |
Ki = 2 nM
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CP0456341
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(4-fluorophenyl)piperazin-1-yl]purine
Show/Hide
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C27H21Cl2FN6
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1
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| 1 |
Ki = 2 nM
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CP0482464
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-pyridin-2-ylpiperazin-1-yl)purine
Show/Hide
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C26H21Cl2N7
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1
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| 1 |
Ki = 2 nM
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CP0489824
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-cyclohexylpiperazin-1-yl)purine
Show/Hide
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C27H28Cl2N6
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1
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| 1 |
Ki = 2 nM
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CP0539037
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4-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]benzonitrile
Show/Hide
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C28H21Cl2N7
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1
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| 1 |
Ki = 2 nM
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CP0539038
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[[2-(trifluoromethoxy)phenyl]methyl]piperazin-1-yl]purine
Show/Hide
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C29H23Cl2F3N6O
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1
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| 1 |
Ki = 2 nM
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CP0539040
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2-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]benzonitrile
Show/Hide
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C28H21Cl2N7
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1
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| 1 |
Ki = 2 nM
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CP0540696
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-phenylpiperazin-1-yl)purine
Show/Hide
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C27H22Cl2N6
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1
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| 1 |
Ki = 2 nM
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CP0540698
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]purine
Show/Hide
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C28H24Cl2N6O
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1
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| 1 |
Ki = 2 nM
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CP0391994
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-2-cyclopentylacetamide
Show/Hide
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C29H30Cl2N6O
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1
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| 1 |
Ki = 2.02 nM
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CP0050487
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(11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalen-1-ylcarbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4(12),5,7-tetraene
Show/Hide
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C27H26N2O3
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2
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| 1 |
Ki = 2.5 nM
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| 2 |
Ki = 8.72 nM
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CP0385623
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phenyl N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]carbamate
Show/Hide
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C29H24Cl2N6O2
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1
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| 1 |
Ki = 2.55 nM
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CP0418248
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}benzamide
Show/Hide
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C29H24Cl2N6O
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1
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| 1 |
Ki = 2.55 nM
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CP0385622
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-4-methylpentanamide
Show/Hide
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C28H30Cl2N6O
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1
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| 1 |
Ki = 2.67 nM
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CP0474039
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tert-butyl 4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
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C27H29Cl3N4O3
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1
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| 1 |
Ki = 2.9 nM
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CP0401263
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-ethyl-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C21H15Cl2F3N4O
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1
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| 1 |
Ki = 3 nM
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CP0392473
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(3-chloropyridin-4-yl)methyl]piperazin-1-yl]purine
Show/Hide
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C27H22Cl3N7
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1
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| 1 |
Ki = 3 nM
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CP0456342
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(4-methoxyphenyl)piperazin-1-yl]purine
Show/Hide
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C28H24Cl2N6O
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1
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| 1 |
Ki = 3 nM
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CP0477938
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2-[[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]methyl]benzonitrile
Show/Hide
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C29H23Cl2N7
|
1
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| 1 |
Ki = 3 nM
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CP0037079
|
lactam-based compound, 12h
Show/Hide
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C20H14Cl2F3N3O
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1
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| 1 |
Ki = 3.1 nM
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CP0441121
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}cyclohexanecarboxamide
Show/Hide
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C29H30Cl2N6O
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1
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| 1 |
Ki = 3.35 nM
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CP0391995
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US9187480, ethyl N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}carbamate
Show/Hide
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C25H24Cl2N6O2
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1
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| 1 |
Ki = 3.57 nM
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CP0541308
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(1-phenyl-1H-imidazol-4-yl)-1H-pyrazole
Show/Hide
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C25H18Cl2N4
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1
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| 1 |
Ki = 3.8 nM
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CP0371733
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(3,3,3-trifluoropropyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C20H13Cl2F3N4O
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1
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| 1 |
Ki = 4 nM
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CP0441836
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[3,4-d]pyridazin-7(6H)-one
Show/Hide
|
C19H11Cl2F3N4O
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1
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| 1 |
Ki = 4 nM
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CP0441837
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6-benzyl-2-(2-chlorophenyl)-3-(4-chlorophenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C24H16Cl2N4O
|
1
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| 1 |
Ki = 4 nM
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CP0449529
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-ethyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H14Cl2N4O
|
1
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| 1 |
Ki = 4 nM
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CP0412604
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(2-methylphenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C29H26Cl2N6
|
1
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| 1 |
Ki = 4 nM
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CP0412607
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl2FN6
|
1
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| 1 |
Ki = 4 nM
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CP0482465
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6-(4-benzylpiperazin-1-yl)-8-(2-chlorophenyl)-9-(4-chlorophenyl)purine
Show/Hide
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C28H24Cl2N6
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1
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| 1 |
Ki = 4 nM
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CP0385620
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-methylbutanamide
Show/Hide
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C27H28Cl2N6O
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1
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| 1 |
Ki = 4.01 nM
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CP0413149
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US9187480, N-tert-butyl-1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-phenylpiperidine-4-carboxamide
Show/Hide
|
C33H32Cl2N6O
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1
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| 1 |
Ki = 4.08 nM
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CP0453395
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N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-N,2-dimethylpropanamide
Show/Hide
|
C24H25Cl2N3O2
|
1
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| 1 |
Ki = 4.3 nM
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CP0497120
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5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-yl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole
Show/Hide
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C25H23Cl3N4
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1
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| 1 |
Ki = 4.7 nM
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CP0037080
|
ether-based lactam, 19b
Show/Hide
|
C21H19Cl2N3O2
|
1
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| 1 |
Ki = 4.8 nM
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CP0392052
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2-fluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H13Cl2FN4O
|
1
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| 1 |
Ki = 5 nM
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CP0373882
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5-(4-chlorophenyl)-3-(1-cyclobutyl-1H-imidazol-4-yl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole
Show/Hide
|
C23H19Cl3N4
|
1
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| 1 |
Ki = 5 nM
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CP0542767
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]purine
Show/Hide
|
C29H23Cl2F3N6
|
1
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| 1 |
Ki = 5 nM
|
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CP0057830
|
5-(4-chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2-methoxyethoxy)pyridine-3-carboxamide
Show/Hide
|
C21H25ClN2O4
|
1
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| 1 |
Ki = 5.1 nM
|
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CP0506328
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-isopropyl-1H-imidazol-2-yl)-4-methyl-1H-pyrazole
Show/Hide
|
C22H19Cl3N4
|
1
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| 1 |
Ki = 5.2 nM
|
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CP0037077
|
lactam-based compound, 12c
Show/Hide
|
C21H19Cl2N3O
|
1
|
| 1 |
Ki = 5.5 nM
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CP0145758
|
8-Chloro-1-(2,4-dichloro-phenyl)-1,3a,4,5,6,10b-hexahydro-1,2-diaza-benzo[e]azulene-3-carboxylic acid piperidin-1-ylamide
Show/Hide
|
C24H23Cl3N4O
|
1
|
| 1 |
Ki = 5.55 nM
|
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CP0459284
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methoxyacetamide
Show/Hide
|
C22H21Cl2N3O3
|
1
|
| 1 |
Ki = 5.6 nM
|
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CP0415524
|
5-(4-Chloro-2-methylphenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H23Cl3N4O
|
1
|
| 1 |
Ki = 5.83 nM
|
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CP0399453
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-phenylpiperidin-4-yl}acetamide
Show/Hide
|
C30H26Cl2N6O
|
1
|
| 1 |
Ki = 6 nM
|
|
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CP0385619
|
US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(trifluoromethanesulfonylmethyl)piperidin-1-yl]-9H-purine
Show/Hide
|
C23H19Cl2F3N6O2S
|
1
|
| 1 |
Ki = 6.1 nM
|
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|
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CP0428013
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]methanesulfonamide
Show/Hide
|
C29H26Cl2N6O2S
|
1
|
| 1 |
Ki = 6.2 nM
|
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CP0442559
|
US9187480, N-{4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexyl}methanesulfonamide
Show/Hide
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C30H27Cl2N5O2S
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1
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| 1 |
Ki = 6.21 nM
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CP0443610
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1-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]pyrrolidin-2-one
Show/Hide
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C23H21Cl2N3O2
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1
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| 1 |
Ki = 6.5 nM
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CP0412596
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2-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]-2-phenylacetonitrile
Show/Hide
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C29H23Cl2N7
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1
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| 1 |
Ki = 7 nM
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CP0540695
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(2-fluorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
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C28H23Cl2FN6
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1
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| 1 |
Ki = 7 nM
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CP0488601
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tert-butyl N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]carbamate
Show/Hide
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C33H32Cl2N6O2
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2
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| 1 |
Ki = 7.1 nM
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| 2 |
Ki = 7.12 nM
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CP0428941
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N-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]methanesulfonamide
Show/Hide
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C29H27Cl3N4O3S
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1
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| 1 |
Ki = 7.3 nM
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CP0517368
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N-[(8S)-2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methylpropanamide
Show/Hide
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C23H23Cl2N3O2
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1
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| 1 |
Ki = 7.5 nM
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CP0122729
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isopropyl-1H-imidazol-4-yl)-4-methyl-1H-pyrazole
Show/Hide
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C22H20Cl2N4
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1
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| 1 |
Ki = 7.6 nM
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CP0410196
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-propylurea
Show/Hide
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C32H32Cl3N5O2
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1
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| 1 |
Ki = 7.6 nM
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CP0373883
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1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-cyclopropyl-1H-imidazol-4-yl)-4-methyl-1H-pyrazole
Show/Hide
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C22H18Cl2N4
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1
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| 1 |
Ki = 7.9 nM
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CP0396686
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-[[4-(methanesulfonamidomethyl)cyclohexyl]methyl]-4-methylpyrazole-3-carboxamide
Show/Hide
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C26H29Cl3N4O3S
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2
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| 1 |
Ki = 8 nM
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| 2 |
Ki = 36 nM
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CP0416807
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(1,5-dimethylpyrazol-4-yl)methyl]piperazin-1-yl]purine
Show/Hide
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C27H26Cl2N8
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1
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| 1 |
Ki = 8 nM
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CP0540697
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-methylphenyl)methyl]piperazin-1-yl]purine
Show/Hide
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C29H26Cl2N6
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1
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| 1 |
Ki = 8 nM
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CP0373866
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-isopropyl-5-methyl-1H-imidazol-4-yl)-4-methyl-1H-pyrazole
Show/Hide
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C23H21Cl3N4
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1
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| 1 |
Ki = 9 nM
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CP0506327
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-isopropyl-1H-imidazol-4-yl)-4-methyl-1H-pyrazole
Show/Hide
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C22H19Cl3N4
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1
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| 1 |
Ki = 9 nM
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CP0428944
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ethyl 4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
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C25H25Cl3N4O3
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1
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| 1 |
Ki = 9.2 nM
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CP0461160
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(2-isopropyl-1H-imidazol-5-yl)-4-methyl-1H-pyrazole
Show/Hide
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C22H19Cl3N4
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1
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| 1 |
Ki = 9.5 nM
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CP0124848
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(6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-6,6-dimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
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C25H38O3
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1
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| 1 |
Ki = 9.55 nM
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CP0158294
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lactam-based compound, 12d
Show/Hide
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C22H21Cl2N3O
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1
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| 1 |
Ki = 9.8 nM
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CP0884639
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-[(3-methyl-5-isoxazolyl)methoxy]-3-pyridinecarboxamide
Show/Hide
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C23H24ClN3O4
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1
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| 1 |
Ki = 10.6 nM
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CP0037078
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lactam-based compound, 12e
Show/Hide
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C22H21Cl2N3O
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1
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| 1 |
Ki = 11 nM
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CP0857532
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cis/trans-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-((4-(methylsulfonamidomethyl)cyclohexyl)methyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C26H29Cl3N4O3S
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2
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| 1 |
Ki = 11 nM
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| 2 |
Ki = 55 nM
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CP0488603
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1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-amine
Show/Hide
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C28H24Cl2N6
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1
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| 1 |
Ki = 11 nM
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CP0500311
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US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexan-1-amine
Show/Hide
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C29H25Cl2N5
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1
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| 1 |
Ki = 11 nM
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CP0851724
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5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 11.4 nM
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CP0410303
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[(3R)-1-methylsulfonylpiperidin-3-yl]pyrazole-3-carboxamide
Show/Hide
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C23H23Cl3N4O3S
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1
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| 1 |
Ki = 11.84 nM
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CP0393593
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]purine
Show/Hide
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C29H26Cl2N6O
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1
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| 1 |
Ki = 12 nM
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CP0412605
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(2-pyridin-4-ylethyl)piperazin-1-yl]purine
Show/Hide
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C28H25Cl2N7
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1
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| 1 |
Ki = 12 nM
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CP0477939
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(1-pyridin-4-ylethyl)piperazin-1-yl]purine
Show/Hide
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C28H25Cl2N7
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1
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| 1 |
Ki = 12 nM
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CP0849154
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide
Show/Hide
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C20H20ClF3N2O3
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1
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| 1 |
Ki = 12.4 nM
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CP0158295
|
lactam-based compound, 12g
Show/Hide
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C23H23Cl2N3O2
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1
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| 1 |
Ki = 13 nM
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CP0371732
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-isopropyl-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C22H17Cl2F3N4O
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1
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| 1 |
Ki = 13 nM
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CP0259522
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5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid pyridin-4-ylamide
Show/Hide
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C22H15Cl3N4O
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2
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| 1 |
Ki = 13 nM
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| 2 |
Ki = 56 nM
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CP0447777
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-propan-2-ylurea
Show/Hide
|
C32H32Cl3N5O2
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1
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| 1 |
Ki = 13.5 nM
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CP0441755
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1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-3-propan-2-ylurea
Show/Hide
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C26H27Cl2N7O
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1
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| 1 |
Ki = 14 nM
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CP0501831
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9-Chloro-1-(2,4-dichlorophenyl)-N-piperidin-1-yl-4,5,6,7-tetrahydro-1H-benzo[7,8]cycloocta[1,2-c]pyrazole-3-carboxamide
Show/Hide
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C25H25Cl3N4O
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1
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| 1 |
Ki = 14.7 nM
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CP0428943
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N-tert-butyl-4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxamide
Show/Hide
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C27H30Cl3N5O2
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1
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| 1 |
Ki = 14.7 nM
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CP0477728
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[[4-[(sulfamoylamino)methyl]cyclohexyl]methyl]pyrazole-3-carboxamide
Show/Hide
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C25H28Cl3N5O3S
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2
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| 1 |
Ki = 15 nM
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| 2 |
Ki = 107 nM
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CP0410195
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-ethylurea
Show/Hide
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C31H30Cl3N5O2
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1
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| 1 |
Ki = 15 nM
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CP0444202
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1-butyl-3-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H34Cl3N5O2
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1
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| 1 |
Ki = 15.5 nM
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CP0874120
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5-(4-Chlorophenyl)-6-(2-cyclopropylethyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C23H27ClN2O2
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1
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| 1 |
Ki = 16.7 nM
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CP0526409
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US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1,4-thiomorpholine-1,1-dione
Show/Hide
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C21H17Cl2N5O2S
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2
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| 1 |
Ki = 16.8 nM
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| 2 |
Ki = 32.1 nM
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CP0430709
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ethyl (3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
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C25H25Cl3N4O3
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1
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| 1 |
Ki = 17.5 nM
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CP0418515
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1,5-bis(2,4-Dichlorophenyl)-4-methyl-N-piperidin-1-yl-1Hpyrazole-3-carboxamide
Show/Hide
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C22H20Cl4N4O
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1
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| 1 |
Ki = 17.9 nM
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CP0893881
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6-(Cyclopropylmethoxy)-5-(4-trifluoromethylphenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H25F3N2O3
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1
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| 1 |
Ki = 18.5 nM
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CP0385621
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US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}pentanamide
Show/Hide
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C27H28Cl2N6O
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1
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| 1 |
Ki = 19.47 nM
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CP0392053
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2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(piperidin-1-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C22H19Cl2N5O
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1
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| 1 |
Ki = 20 nM
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CP0440585
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[7-(sulfamoylamino)heptyl]pyrazole-3-carboxamide
Show/Hide
|
C24H28Cl3N5O3S
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2
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| 1 |
Ki = 20 nM
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| 2 |
Ki = 49 nM
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CP0473553
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[[4-[(sulfamoylamino)methyl]cyclohexyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H28Cl3N5O3S
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2
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| 1 |
Ki = 21 nM
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| 2 |
Ki = 135 nM
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CP0392474
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8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(pyridin-4-ylmethyl)piperazin-1-yl]purine
Show/Hide
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C27H23Cl2N7
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1
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| 1 |
Ki = 22 nM
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CP0423937
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tert-butyl (3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
|
C27H29Cl3N4O3
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1
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| 1 |
Ki = 22.3 nM
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CP0953332
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(3-pyridinylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C24H24ClN3O3
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1
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| 1 |
Ki = 23.5 nM
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CP0851727
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5-(4-Cyanophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C23H25N3O3
|
1
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| 1 |
Ki = 23.6 nM
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CP0901741
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6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-[4-(trifluoromethoxy)phenyl]-3-pyridinecarboxamide
Show/Hide
|
C23H25F3N2O4
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1
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| 1 |
Ki = 23.6 nM
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CP0428015
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tert-butyl 4-[[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]amino]piperidine-1-carboxylate
Show/Hide
|
C27H28Cl2N6O2
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2
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| 1 |
Ki = 23.91 nM
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| 2 |
Ki = 24 nM
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CP0475976
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3-[[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]methyl]-5-methyl-1,2,4-oxadiazole
Show/Hide
|
C25H22Cl2N8O
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1
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| 1 |
Ki = 24 nM
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CP0520693
|
lactam-based compound, 12b
Show/Hide
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C20H17Cl2N3O
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1
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| 1 |
Ki = 25 nM
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CP0481688
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1-butyl-3-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]urea
Show/Hide
|
C27H29Cl2N7O
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1
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| 1 |
Ki = 25 nM
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CP0456334
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3-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]phenol
Show/Hide
|
C27H22Cl2N6O
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1
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| 1 |
Ki = 25 nM
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CP0428012
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1-tert-butyl-3-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H33Cl2N7O
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1
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| 1 |
Ki = 25.5 nM
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CP0851726
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6-(4-Chlorophenyl)-5-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxy-cyclohexyl]-pyrazine-2-carboxamide
Show/Hide
|
C21H24ClN3O3
|
1
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| 1 |
Ki = 25.8 nM
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CP0440586
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(6-methylpyridin-3-yl)pyrazole-3-carboxamide
Show/Hide
|
C23H17Cl3N4O
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2
|
| 1 |
Ki = 26 nM
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| 2 |
Ki = 102 nM
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CP0486959
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-3-propylurea
Show/Hide
|
C26H27Cl2N7O
|
1
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| 1 |
Ki = 28 nM
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CP0413829
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]methanesulfonamide
Show/Hide
|
C23H22Cl2N6O2S
|
1
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| 1 |
Ki = 29 nM
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CP0901736
|
5-(4-Chlorophenyl)-N-[(2R)-2-cyclopropyl-2-hydroxypropyl]-6-(cyclopropylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
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| 1 |
Ki = 34.3 nM
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CP0504314
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-hexylurea
Show/Hide
|
C35H38Cl3N5O2
|
1
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| 1 |
Ki = 38.8 nM
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CP0410197
|
N-[(3S)-1-acetylpiperidin-3-yl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C24H23Cl3N4O2
|
1
|
| 1 |
Ki = 39.1 nM
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CP0943808
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(phenylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C25H25ClN2O3
|
1
|
| 1 |
Ki = 40.2 nM
|
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CP0428940
|
tert-butyl N-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]carbamate
Show/Hide
|
C33H33Cl3N4O3
|
1
|
| 1 |
Ki = 42.3 nM
|
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CP0884635
|
6-(Cyclopropylmethoxy)-5-(4-fluorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25FN2O3
|
1
|
| 1 |
Ki = 42.8 nM
|
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CP0427061
|
1-benzyl-3-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C36H32Cl3N5O2
|
1
|
| 1 |
Ki = 43 nM
|
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CP0868207
|
6-Butoxy-5-(4-chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H27ClN2O3
|
1
|
| 1 |
Ki = 43.8 nM
|
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CP0441119
|
US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}methyl)cyclohexyl]methyl}methanesulfonamide
Show/Hide
|
C26H28Cl2N6O2S
|
2
|
| 1 |
Ki = 44.5 nM
|
|
|
| 2 |
Ki = 258 nM
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CP0428942
|
1-tert-butyl-3-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H34Cl3N5O2
|
1
|
| 1 |
Ki = 47.1 nM
|
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CP0899224
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5-(4-Chlorophenyl)-6-[(cyclopropylmethyl)methylamino]-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C23H28ClN3O2
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1
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| 1 |
Ki = 51.1 nM
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CP0866739
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2-pyrimidinylmethoxy)-3-pyridinecarboxamide
Show/Hide
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C23H23ClN4O3
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1
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| 1 |
Ki = 51.6 nM
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CP0946962
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(4-pyridinylmethoxy)-3-pyridinecarboxamide
Show/Hide
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C24H24ClN3O3
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1
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| 1 |
Ki = 58.7 nM
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CP0449302
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-[7-(methanesulfonamido)heptyl]-4-methylpyrazole-3-carboxamide
Show/Hide
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C25H29Cl3N4O3S
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2
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| 1 |
Ki = 60 nM
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| 2 |
Ki = 158 nM
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CP0500549
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-(1-hydroxypyridin-4-ylidene)-4-methylpyrazole-3-carboxamide
Show/Hide
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C22H15Cl3N4O2
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2
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| 1 |
Ki = 61 nM
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| 2 |
Ki = 294 nM
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CP0410307
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N-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]acetamide
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C30H27Cl3N4O2
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1
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| 1 |
Ki = 62.6 nM
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CP0444475
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N-(1-acetylpiperidin-4-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
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C24H23Cl3N4O2
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1
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| 1 |
Ki = 65.3 nM
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CP0409458
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ethyl (3S)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
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C25H25Cl3N4O3
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1
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| 1 |
Ki = 65.5 nM
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CP0866737
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6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-(4-methoxyphenyl)-3-pyridinecarboxamide
Show/Hide
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C23H28N2O4
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1
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| 1 |
Ki = 66.4 nM
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CP0866738
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5-[2-Chloro-5-(trifluoromethyl)phenyl]-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C23H24ClF3N2O3
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1
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| 1 |
Ki = 67.7 nM
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CP0385359
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[(3S)-1-methylsulfonylpiperidin-3-yl]pyrazole-3-carboxamide
Show/Hide
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C23H23Cl3N4O3S
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1
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| 1 |
Ki = 77.9 nM
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CP0410194
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1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-(ethylamino)piperidine-4-carboxamide
Show/Hide
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C25H26Cl3N5O2
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1
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| 1 |
Ki = 78.4 nM
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CP0474072
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4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propan-2-ylpiperidine-1-carboxamide
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C26H28Cl3N5O2
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1
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| 1 |
Ki = 86 nM
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CP0441118
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US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}methyl)cyclohexyl]methyl}aminosulfonamide
Show/Hide
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C25H27Cl2N7O2S
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2
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| 1 |
Ki = 94.5 nM
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| 2 |
Ki = 355 nM
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CP0410306
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(3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propan-2-ylpiperidine-1-carboxamide
Show/Hide
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C26H28Cl3N5O2
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1
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| 1 |
Ki = 97 nM
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CP0444204
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(4-amino-4-phenylpiperidin-1-yl)-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazol-3-yl]methanone
Show/Hide
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C28H25Cl3N4O
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1
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| 1 |
Ki = 104 nM
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CP0868208
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5-(4-Chloro-phenyl)-6-cyclopropylmethoxy-N-((1S,2R)-2-hydroxy-cyclohexyl)-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 104 nM
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CP0465702
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5-(4-Chloro-2,6-dimethylphenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide
Show/Hide
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C24H25Cl3N4O
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1
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| 1 |
Ki = 116 nM
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CP0884638
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6-(Cyclopropylmethoxy)-5-(2,4-dichlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H24Cl2N2O3
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1
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| 1 |
Ki = 122 nM
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CP0427068
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(3R)-N-butyl-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxamide
Show/Hide
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C27H30Cl3N5O2
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1
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| 1 |
Ki = 125 nM
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CP0893868
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5-(3-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 129 nM
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CP0409459
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(3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propylpiperidine-1-carboxamide
Show/Hide
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C26H28Cl3N5O2
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1
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| 1 |
Ki = 134 nM
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CP0893882
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2-pyridinylmethoxy)-3-pyridinecarboxamide
Show/Hide
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C24H24ClN3O3
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1
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| 1 |
Ki = 139 nM
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CP0373943
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5-(2,4-Dichlorophenyl)-4-methyl-N-piperidin-1-yl-1-(2,4,6-trichlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C22H19Cl5N4O
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1
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| 1 |
Ki = 148 nM
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CP0419054
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5-(4-Chloro-2-methylphenyl)-4-methyl-N-piperidin-1-yl-1-(2,4,6-trichlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C23H22Cl4N4O
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1
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| 1 |
Ki = 152 nM
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CP0428939
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4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-ethylpiperidine-1-carboxamide
Show/Hide
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C25H26Cl3N5O2
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1
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| 1 |
Ki = 165 nM
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CP0444203
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4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propylpiperidine-1-carboxamide
Show/Hide
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C26H28Cl3N5O2
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1
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| 1 |
Ki = 184 nM
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CP0953345
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5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2S)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 186 nM
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CP0447778
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N-butyl-4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxamide
Show/Hide
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C27H30Cl3N5O2
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1
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| 1 |
Ki = 187 nM
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CP0893915
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5-(2-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 190 nM
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CP0413825
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1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]-3-ethylurea
Show/Hide
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C31H29Cl2N7O
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1
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| 1 |
Ki = 195 nM
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CP0884636
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5-(4-Chlorophenyl)-6-cyclobutoxy-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 208 nM
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CP0428011
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1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]-3-propylurea
Show/Hide
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C32H31Cl2N7O
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1
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| 1 |
Ki = 220 nM
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CP0902668
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5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1S,2S)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 247 nM
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CP0659893
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(Z)-2-(3-(4-chlorobenzyloxy)benzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C21H19ClN2O2S
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1
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| 1 |
Ki = 250 nM
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CP0487976
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1-butyl-3-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]urea
Show/Hide
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C33H33Cl2N7O
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1
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| 1 |
Ki = 269 nM
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CP0432562
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(3S)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propylpiperidine-1-carboxamide
Show/Hide
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C26H28Cl3N5O2
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1
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| 1 |
Ki = 271 nM
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CP0868210
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6-(Cyclopropylmethoxy)-5-(3,4-dichlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C22H24Cl2N2O3
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1
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| 1 |
Ki = 305 nM
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CP0386827
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(2E,4E,9E,12E)-N-(2-methylbutyl)hexadeca-2,4,9,12-tetraenamide
Show/Hide
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C21H35NO
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1
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| 1 |
Ki = 310 nM
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CP0487977
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1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]-3-propan-2-ylurea
Show/Hide
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C32H31Cl2N7O
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1
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| 1 |
Ki = 337 nM
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CP0882319
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5-(4-Chlorophenyl)-6-(cyclopentyloxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C23H27ClN2O3
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1
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| 1 |
Ki = 374 nM
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CP0078849
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(9Z,12Z)-N-benzyloctadeca-9,12-dienamide
Show/Hide
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C25H39NO
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1
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| 1 |
Ki = 480 nM
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CP0849147
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5-(4-Chloro-phenyl)-6-cyclopropylmethoxy-N-piperidin-1-yl-3-pyridinecarboxamide
Show/Hide
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C21H24ClN3O2
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1
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| 1 |
Ki = 563 nM
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CP0374915
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3-[(4-chlorophenyl)methyl]-5-methoxy-7-pentylchromen-2-one
Show/Hide
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C22H23ClO3
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1
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| 1 |
Ki = 613 nM
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CP0434935
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-(4-fluorophenyl)urea
Show/Hide
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C35H29Cl3FN5O2
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1
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| 1 |
Ki = 614 nM
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CP0920612
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5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamido)-1,2-dimethylpyridinium iodide
Show/Hide
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C24H20Cl3IN4O
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2
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| 1 |
Ki = 786 nM
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| 2 |
Ki = 1698 nM
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CP0437612
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-cyclohexylurea
Show/Hide
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C35H36Cl3N5O2
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1
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| 1 |
Ki = 792 nM
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CP0868782
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(Z)-2-(3-(4-Fluorobenzyloxy)benzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C21H19FN2O2S
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1
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| 1 |
Ki = 850 nM
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CP0375364
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(9R)-3,6,6,9-tetramethyl-7,8,9,10-tetrahydrobenzo[c]chromen-1-ol
Show/Hide
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C17H22O2
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1
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| 1 |
Ki = 1000 nM
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CP0368793
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3-dodecanoyl-4-hydroxy-5-(4-hydroxyphenyl)-1H-pyridin-2-one
Show/Hide
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C23H31NO4
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1
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| 1 |
Ki = 1000 nM
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CP0893869
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(1-methylethoxy)-3-pyridinecarboxamide
Show/Hide
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C21H25ClN2O3
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1
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| 1 |
Ki = 1074 nM
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CP0379220
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(6R)-6,9,9-trimethyl-3-pentyl-5,6,7,8-tetrahydroxanthen-1-ol
Show/Hide
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C21H30O2
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1
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| 1 |
Ki = 1100 nM
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CP0859210
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2,2-diphenyl-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C19H18N2OS
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1
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| 1 |
Ki = 1340 nM
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CP0410301
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1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-[4-(dimethylamino)phenyl]urea
Show/Hide
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C37H35Cl3N6O2
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1
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| 1 |
Ki = 1489 nM
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CP0881784
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(Z)-2-(3-phenoxybenzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C20H18N2O2S
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1
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| 1 |
Ki = 1600 nM
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CP0851725
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5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(phenoxy)-3-pyridinecarboxamide
Show/Hide
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C24H23ClN2O3
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1
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| 1 |
Ki = 1657 nM
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CP0901735
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6-(4-Chlorophenyl)-5-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-2-pyridinecarboxamide
Show/Hide
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C22H25ClN2O3
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1
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| 1 |
Ki = 1830 nM
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CP0911979
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6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-(4-methanesulfonylamino-phenyl)-3-pyridinecarboxamide
Show/Hide
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C23H29N3O5S
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1
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| 1 |
Ki = 1900 nM
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CP0859209
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(Z)-2-(3-(2,4-Dichlorobenzyloxy)benzylidene)-6,7-dihydro-2Himidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
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C20H16Cl2N2O2S
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1
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| 1 |
Ki = 2090 nM
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CP0375367
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(6S)-6,9,9-trimethyl-3-pentyl-5,6,7,8-tetrahydroxanthen-1-ol
Show/Hide
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C21H30O2
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1
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| 1 |
Ki = 2100 nM
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CP0900469
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(Z)-2-(3-(Benzyloxy)benzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C21H20N2O2S
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1
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| 1 |
Ki = 2130 nM
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CP0709769
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(Z)-2-(3-(3-Chlorobenzyloxy)benzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C21H19ClN2O2S
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1
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| 1 |
Ki = 2160 nM
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CP0433639
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2,6-ditert-butyl-4-[2-[4-(methylamino)oxan-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
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C23H34N2O2S
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1
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| 1 |
Ki = 2273 nM
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CP0898591
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(Z)-2-(3-(2-Chlorobenzyloxy)benzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C21H19ClN2O2S
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1
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| 1 |
Ki = 2290 nM
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CP0893867
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5-(4-Chlorophenyl)-6-(cyclohexyloxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C24H29ClN2O3
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1
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| 1 |
Ki = 3035 nM
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CP0849218
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(Z)-2-(3-(2,4-dichlorobenzyloxy)benzylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
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C21H18Cl2N2O2S
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1
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| 1 |
Ki = 3180 nM
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CP0441756
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N-butyl-4-[[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]amino]piperidine-1-carboxamide
Show/Hide
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C27H29Cl2N7O
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1
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| 1 |
Ki = 3343 nM
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CP0375172
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6-methoxy-3-[(2-methoxyphenyl)methyl]-5,7,8-trimethylchromen-2-one
Show/Hide
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C21H22O4
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1
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| 1 |
Ki = 3660 nM
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CP0431624
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4-[4-(3,5-ditert-butylphenyl)-1,3-thiazol-2-yl]-N,N-dimethyloxan-4-amine
Show/Hide
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C24H36N2OS
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1
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| 1 |
Ki = 4710 nM
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CP0859208
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(Z)-ethyl 2-(3-((3-oxo-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-2(3H)-ylidene)methyl)phenoxy)acetate
Show/Hide
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C18H20N2O4S
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1
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| 1 |
Ki = 4780 nM
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CP0415521
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4-[2-(4-aminooxan-4-yl)-1,3-thiazol-4-yl]-2,6-ditert-butylphenol
Show/Hide
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C22H32N2O2S
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1
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| 1 |
Ki = 6957 nM
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CP0393598
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6-methoxy-5,7,8-trimethyl-3-[(2-methylphenyl)methyl]chromen-2-one
Show/Hide
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C21H22O3
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1
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| 1 |
Ki = 7860 nM
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CP0445160
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(2E,4E,8E,10Z,14Z)-N-(2-methylpropyl)octadeca-2,4,8,10,14-pentaen-12-ynamide
Show/Hide
|
C22H31NO
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1
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| 1 |
Ki = 8600 nM
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CP0233117
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(9Z,12Z,15Z)-N-[(3-methoxyphenyl)methyl]octadeca-9,12,15-trienamide
Show/Hide
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C26H39NO2
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1
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| 1 |
Ki = 8670 nM
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CP0261493
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(9Z,12Z,15Z)-N-benzyloctadeca-9,12,15-trienamide
Show/Hide
|
C25H37NO
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1
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| 1 |
Ki = 8880 nM
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CP0375105
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7-(1-butylcyclohexyl)-5-methoxy-3-[(2-methoxyphenyl)methyl]chromen-2-one
Show/Hide
|
C28H34O4
|
1
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| 1 |
Ki >= 10000 nM
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CP0375117
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3-benzyl-6-hydroxy-5,7,8-trimethylchromen-2-one
Show/Hide
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C19H18O3
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1
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| 1 |
Ki > 10000 nM
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CP0375124
|
3-Benzyl-5-isopropyl-8-methylchromen-2-one
Show/Hide
|
C20H20O2
|
1
|
| 1 |
Ki > 10000 nM
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CP0375125
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6-hydroxy-5,7,8-trimethyl-3-[(2-methylphenyl)methyl]chromen-2-one
Show/Hide
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C20H20O3
|
1
|
| 1 |
Ki >= 10000 nM
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CP0375165
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5-methoxy-3-[(2-methoxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one
Show/Hide
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C28H36O4
|
1
|
| 1 |
Ki = 10000 nM
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CP0375166
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3-[(2-methoxyphenyl)methyl]-5-methyl-8-propan-2-ylchromen-2-one
Show/Hide
|
C21H22O3
|
1
|
| 1 |
Ki > 10000 nM
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CP0375171
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3-[(4-fluorophenyl)methyl]-6-hydroxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C19H17FO3
|
1
|
| 1 |
Ki > 10000 nM
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CP0391309
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7-bromo-5-methoxy-3-[(3-methoxyphenyl)methyl]chromen-2-one
Show/Hide
|
C18H15BrO4
|
1
|
| 1 |
Ki > 10000 nM
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CP0393582
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3-Benzyl-5-methoxy-7-methylchromen-2-one
Show/Hide
|
C18H16O3
|
1
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| 1 |
Ki >= 10000 nM
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CP0393584
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3-[(2-hydroxyphenyl)methyl]-8-methyl-5-propan-2-ylchromen-2-one
Show/Hide
|
C20H20O3
|
1
|
| 1 |
Ki > 10000 nM
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CP0393599
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3-[(2-methoxyphenyl)methyl]-5,8-dimethylchromen-2-one
Show/Hide
|
C19H18O3
|
1
|
| 1 |
Ki > 10000 nM
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|
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CP0393614
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5-Isopropyl-3,8-dimethylchromen-2-one
Show/Hide
|
C14H16O2
|
1
|
| 1 |
Ki > 10000 nM
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CP0394936
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3-[(4-fluorophenyl)methyl]-6-methoxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C20H19FO3
|
1
|
| 1 |
Ki = 10000 nM
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CP0409866
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3-benzyl-6-methoxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C20H20O3
|
1
|
| 1 |
Ki >= 10000 nM
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CP0868209
|
6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-(4-sulfamoyl-phenyl)-3-pyridinecarboxamide
Show/Hide
|
C22H27N3O5S
|
1
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| 1 |
Ki > 10000 nM
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CP0884637
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4-[2-Cyclopropylmethoxy-5-((1R,2R)-2-hydroxy-cyclohexylcarbamoyl)-pyridin-3-yl]-benzoic Acid
Show/Hide
|
C23H26N2O5
|
1
|
| 1 |
Ki > 10000 nM
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CP0125632
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((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic acid
Show/Hide
|
C22H35NO3
|
1
|
| 1 |
Ki > 10000 nM
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CP0659851
|
(Z)-2-(2,4-dimethoxybenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C15H16N2O3S
|
1
|
| 1 |
Ki >= 10000 nM
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CP0659892
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(Z)-2-(3-(4-Chlorobenzyloxy)benzylidene)-6,7-dihydro-2H-imidazo-[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C20H17ClN2O2S
|
1
|
| 1 |
Ki > 10000 nM
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CP0659958
|
(Z)-2-(2-chlorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11ClN2OS
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0677588
|
(Z)-2-benzylidene-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H12N2OS
|
1
|
| 1 |
Ki > 10000 nM
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|
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CP0692927
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(Z)-2-(2,3-Difluorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b]-[1,3]thiazin-3(5H)-one
Show/Hide
|
C13H10F2N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849166
|
(Z)-2-(4-bromobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11BrN2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849167
|
(Z)-2-(3-(Benzyloxy)benzylidene)-6,7-dihydro-2H-imidazo-[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C20H18N2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849168
|
(Z)-2-(4-methoxybenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C14H14N2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849169
|
(Z)-2-(2,4-Difluorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b]-[1,3]thiazin-3(5H)-one
Show/Hide
|
C13H10F2N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849409
|
(Z)-2-(2-methoxybenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C14H14N2O2S
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0849467
|
(Z)-2-(3-phenoxybenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C19H16N2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0849468
|
(Z)-2-(3,4-dimethoxybenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C15H16N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0849470
|
(Z)-2-(3-nitrobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11N3O3S
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0849472
|
(Z)-2-(3-phenylallylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C15H14N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849480
|
(Z)-3-(3-phenylallylidene)-3,5,6,7-tetrahydro-2H-imidazo[2,1-b][1,3]thiazin-2-one
Show/Hide
|
C15H14N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0849481
|
1-lysophosphatidylinositol
Show/Hide
|
C29H49O12P
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0850010
|
(Z)-2-(2,6-Dichlorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b]-[1,3]thiazin-3(5H)-one
Show/Hide
|
C13H10Cl2N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0858888
|
(Z)-2-(2,3-dichlorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H10Cl2N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0858889
|
(Z)-2-(4-isopropylbenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C16H18N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859207
|
(Z)-2-(4-chlorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11ClN2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859211
|
ethyl 5-oxo-6,6-diphenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole-2-carboxylate
Show/Hide
|
C20H18N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859212
|
2,2-diphenyl-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C18H16N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859457
|
(Z)-2-(3-chlorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11ClN2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859466
|
(Z)-3-((3-Oxo-6,7-dihydro-3H-imidazo[2,1-b][1,3]thiazin-2(5H)-ylidene)methyl)phenyl 4-chloro-benzoate
Show/Hide
|
C20H15ClN2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859468
|
(Z)-2-(2,4-Dichlorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b]-[1,3]-thiazin-3(5H)-one
Show/Hide
|
C13H10Cl2N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859481
|
(Z)-2-(biphenyl-4-ylmethylene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
|
C20H18N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0859491
|
3,3-diphenyl-3,5,6,7-tetrahydro-2H-imidazo[2,1-b][1,3]thiazin-2-one
Show/Hide
|
C18H16N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0866547
|
ethyl 6-oxo-5,5-diphenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole-2-carboxylate
Show/Hide
|
C20H18N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0866629
|
3,3-diphenyl-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-2(3H)-one
Show/Hide
|
C19H18N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0866766
|
5,5-diphenyl-2,3-dihydroimidazo[2,1-b]thiazol-6(5H)-one
Show/Hide
|
C17H14N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0866767
|
(Z)-2-(1-phenylethylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3(2H)-one
Show/Hide
|
C15H16N2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0867263
|
(Z)-2-(4-nitrobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11N3O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0868197
|
(Z)-2-(3-(3,4-Dichlorobenzyloxy)benzylidene)-6,7-dihydro-2Himidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C20H16Cl2N2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0868783
|
(Z)-2-(4-(dimethylamino)benzylidene)-6,7-dihydro-2H-imidazo[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C15H17N3OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0877023
|
(Z)-2-(3-(2-Chlorobenzyloxy)benzylidene)-6,7-dihydro-2H-imidazo-[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C20H17ClN2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0893067
|
(Z)-3-((3-oxo-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-2(3H)-ylidene)methyl)phenyl 4-methylbenzoate
Show/Hide
|
C22H20N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0893073
|
(Z)-3-((3-Oxo-6,7-dihydro-3H-imidazo[2,1-b][1,3]thiazin-2(5H)-ylidene)methyl)phenyl benzoate
Show/Hide
|
C20H16N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0905395
|
(Z)-2-(2-Fluorobenzylidene)-6,7-dihydro-2H-imidazo[2,1-b]-[1,3]thiazin-3(5H)-one
Show/Hide
|
C13H11FN2OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0916683
|
(Z)-2-(2,3-Dimethoxybenzylidene)-6,7-dihydro-2H-imidazo-[2,1-b][1,3]thiazin-3(5H)-one
Show/Hide
|
C15H16N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0375363
|
(6R)-2-ethyl-6,9,9-trimethyl-5,6,7,8-tetrahydroxanthen-3-ol
Show/Hide
|
C18H24O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375365
|
(6R)-3,6,9,9-tetramethyl-5,6,7,8-tetrahydroxanthen-1-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375366
|
(9R)-4,6,6,9-tetramethyl-7,8,9,10-tetrahydrobenzo[c]chromen-3-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375368
|
(9R)-6,6,9-trimethyl-7,8,9,10-tetrahydrobenzo[c]chromen-3-ol
Show/Hide
|
C16H20O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0379221
|
(6R)-6,9,9-trimethyl-5,6,7,8-tetrahydroxanthen-3-ol
Show/Hide
|
C16H20O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0400268
|
(6R)-4,6,9,9-tetramethyl-5,6,7,8-tetrahydroxanthen-3-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0455894
|
(9R)-2-ethyl-6,6,9-trimethyl-7,8,9,10-tetrahydrobenzo[c]chromen-3-ol
Show/Hide
|
C18H24O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0399621
|
1-(2-ethoxyethyl)-N-(3-hydroxy-1-adamantyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C25H32N2O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0399622
|
1-(2-ethoxyethyl)-8-methoxy-4-oxo-N-(2-phenylethyl)quinoline-3-carboxamide
Show/Hide
|
C23H26N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0399623
|
N-(1-adamantyl)-1-(2-ethoxyethyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C25H32N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0472350
|
N-tert-butyl-1-butyl-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C19H26N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0472351
|
N-(1-adamantyl)-1-butyl-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476824
|
N-tert-butyl-1-(3-fluoropropyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C18H23FN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476825
|
1-butyl-N-cyclopentyl-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0480579
|
N-(1-adamantyl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide
Show/Hide
|
C26H34N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0561027
|
1-butyl-N-(cyclopropylmethyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C19H24N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0393585
|
3-[(4-bromophenyl)methyl]-5-methoxy-7-pentylchromen-2-one
Show/Hide
|
C22H23BrO3
|
1
|
| 1 |
Ki = 10200 nM
|
|
|
|
CP0424530
|
(2E,4E,9Z)-N-(2-methylpropyl)hexadeca-2,4,9-trien-12,14-diynamide
Show/Hide
|
C20H27NO
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0849399
|
6,6-diphenyl-2,3-dihydroimidazo[2,1-b]thiazol-5(6H)-one
Show/Hide
|
C17H14N2OS
|
1
|
| 1 |
Ki = 21100 nM
|
|
|
|
CP0051977
|
decyl 4-hydroxy-5-(4-hydroxyphenyl)-2-oxo-1H-pyridine-3-carboxylate
Show/Hide
|
C22H29NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0235951
|
4-hydroxy-5-(4-hydroxyphenyl)-3-octadecanoyl-1H-pyridin-2-one
Show/Hide
|
C29H43NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0306281
|
FARINOSONE A
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0378922
|
4-hydroxy-5-(4-hydroxyphenyl)-3-octanoyl-1H-pyridin-2-one
Show/Hide
|
C19H23NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0895354
|
5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-pyridazine-3-carboxamide
Show/Hide
|
C21H24ClN3O3
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0849146
|
4-(4-Chlorophenyl)-5-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-2-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 7000 nM
|
|
|
|
CP0898833
|
5-(4-Carbamoyl-phenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
Ki > 8000 nM
|
|
|
