General Information of the Compound
Compound ID
CP0535551
Compound Name
1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2,4-dichlorobenzyl)-1H-pyrazole-3-carboxamide
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Structure
Formula
C25H16Cl4N4O
Molecular Weight
530.242
Canonical SMILES
Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NCc1ccc(Cl)cc1Cl
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InChI
InChI=1S/C25H16Cl4N4O/c26-17-8-5-15(6-9-17)24-19(11-12-30)23(32-33(24)22-4-2-1-3-20(22)28)25(34)31-14-16-7-10-18(27)13-21(16)29/h1-10,13H,11,14H2,(H,31,34)
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InChIKey
FQGBQADTBADEJY-UHFFFAOYSA-N
Physicochemical Property
logP
7.14898
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
70.71
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46224774
ChEMBL ID
CHEMBL589893
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.6 nM
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