General Information of the Compound
Compound ID
CP0497120
Compound Name
5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-yl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole
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Structure
Formula
C25H23Cl3N4
Molecular Weight
485.846
Canonical SMILES
Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1cn(cn1)C1CCCCC1
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InChI
InChI=1S/C25H23Cl3N4/c1-16-24(22-14-31(15-29-22)20-5-3-2-4-6-20)30-32(23-12-11-19(27)13-21(23)28)25(16)17-7-9-18(26)10-8-17/h7-15,20H,2-6H2,1H3
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InChIKey
DTBAXFXZDCEJJK-UHFFFAOYSA-N
Physicochemical Property
logP
8.17662
Rotatable Bonds
4
Heavy Atom Count
32
Polar Areas
35.64
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45484794
ChEMBL ID
CHEMBL585095
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 4.7 nM
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