Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-3-ethyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-1H-indole-2-carboxamide
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 PubChem ID
CID: 44828492
Canonical SMILES
CCc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1
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Compound Formula C24H28ClN3O
Compound Structure
Protein Name
 Protein Info 
Cannabinoid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Cannabinoid receptor
Uniprot ID
P21554
Gene Name
CNR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 83 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 9.05 nM
   TI
   LI
   LO
   TS
2
EC50 = 324 nM
   TI
   LI
   LO
   TS
3
IC50 = 2 nM
   TI
   LI
   LO
   TS
CL000076 CHO/Galpha16
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 794.33 nM
   TI
   LI
   LO
   TS
2
IC50 = 853 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  6
1
EC50 = 140 nM
   TI
   LI
   LO
   TS
2
EC50 = 640 nM
   TI
   LI
   LO
   TS
3
EC50 = 2090 nM
   TI
   LI
   LO
   TS
4
EC50 = 2240 nM
   TI
   LI
   LO
   TS
5
EC50 = 10590 nM
   TI
   LI
   LO
   TS
6
IC50 = 158.49 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 853 nM