General Information of the Compound
Compound ID
CP0533978
Compound Name
1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(4-fluorophenyl)-4-(2-(hydroxyamino)-2-iminoethyl)-1H-pyrazole-3-carboxamide
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Structure
Formula
C24H18Cl2FN5O2
Molecular Weight
498.345
Canonical SMILES
ONC(=N)Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1Cl)C(=O)Nc1ccc(F)cc1
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InChI
InChI=1S/C24H18Cl2FN5O2/c25-15-7-5-14(6-8-15)23-18(13-21(28)31-34)22(24(33)29-17-11-9-16(27)10-12-17)30-32(23)20-4-2-1-3-19(20)26/h1-12,34H,13H2,(H2,28,31)(H,29,33)
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InChIKey
BLAXJIFUGFVCLM-UHFFFAOYSA-N
Physicochemical Property
logP
5.73607
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
103.03
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46226249
ChEMBL ID
CHEMBL595232
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.1 nM
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