| Compound ID |
Compound Name |
Compound Formula |
|
CP0414301
|
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]cyclopentyl]-N-methylsulfonylhept-5-enamide
Show/Hide
|
C23H33NO7S
|
1
|
| 1 |
EC50 = 0.34 nM
|
|
|
|
CP0182637
|
2-[2-[(4S)-4-[(E,3R)-3-[1-(4-fluorobutyl)cyclobutyl]-3-hydroxyprop-1-enyl]-2-oxo-1,3-oxazolidin-3-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H27FN2O5S2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0847317
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C22H25NO6S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0415590
|
2-[2-[(1R,2R)-2-[(E,4S)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H29NO4S2
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0451962
|
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
Show/Hide
|
C22H28O6
|
1
|
| 1 |
EC50 = 0.89 nM
|
|
|
|
CP0523517
|
2-[2-[(1R,2R)-2-[(E,4S)-4-hydroxy-4-methylnon-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H31NO4S2
|
1
|
| 1 |
EC50 = 0.91 nM
|
|
|
|
CP0415586
|
2-[2-[(1R,2R)-2-[(E,4S)-5-cyclopentyl-4-hydroxy-4-methylpent-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C22H31NO4S2
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0446134
|
4-[(3R,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]butanoic acid
Show/Hide
|
C23H32O6
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0055947
|
(15S)-prostaglandin E2
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|
C20H32O5
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0415587
|
2-[2-[(1R,2R)-2-[(E)-4-hydroxy-4-methylnon-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H31NO4S2
|
1
|
| 1 |
EC50 = 2.7 nM
|
|
|
|
CP0415589
|
2-[2-[(1R,2R)-2-[(E,4S)-8-fluoro-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H28FNO4S2
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0482357
|
2-[2-[(4S)-4-[(E)-4-hydroxy-4-methylnon-1-enyl]-2-oxo-1,3-oxazolidin-3-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C19H28N2O5S2
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0407879
|
2-[2-[(1R,2R)-2-[(E,4S)-4-hydroxy-4,7,7-trimethyloct-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C22H33NO4S2
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0450782
|
2-[2-[(1R,5R)-2-oxo-5-[(E,4S)-7,7,7-trifluoro-4-hydroxy-4-methylhept-1-enyl]cyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C19H24F3NO4S2
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0858586
|
4-((2S,4aR,5R,6R,7aS)-6-hydroxy-5-((R,E)-3-hydroxy-4-phenoxybut-1-enyl)octahydrocyclopenta[b]pyran-2-yl)butanoic acid
Show/Hide
|
C22H30O6
|
1
|
| 1 |
EC50 = 3.6 nM
|
|
|
|
CP0089845
|
4-[(3S,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]butanoic acid
Show/Hide
|
C23H32O6
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0398632
|
4-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]butanoic acid
Show/Hide
|
C22H30O6
|
1
|
| 1 |
EC50 = 4.1 nM
|
|
|
|
CP0415588
|
2-[2-[(4S)-4-[(E)-5-cyclohexyl-4-hydroxy-4-methylpent-1-enyl]-2-oxo-1,3-oxazolidin-3-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H30N2O5S2
|
1
|
| 1 |
EC50 = 8.8 nM
|
|
|
|
CP0383051
|
5-[(5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5,5a,6,7,8,8a-hexahydro-2H-cyclopenta[b]oxepin-3-yl]pentanoic acid
Show/Hide
|
C24H32O6
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0396047
|
2-[2-[(1R,2R)-2-[(E,4R)-4-hydroxy-4-methylnon-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H31NO4S2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0517457
|
3-[(2R,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-2-yl]propanoic acid
Show/Hide
|
C22H30O6
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0398630
|
3-[(2S,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-2-yl]propanoic acid
Show/Hide
|
C22H30O6
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0407877
|
2-[2-[(1R,2R)-2-[(E,4R)-5-cyclopentyl-4-hydroxy-4-methylpent-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C22H31NO4S2
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0407876
|
2-[2-[(4S,5S)-4-[(E)-5-cyclohexyl-4-hydroxy-4-methylpent-1-enyl]-5-methyl-2-oxo-1,3-oxazolidin-3-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C22H32N2O5S2
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0504418
|
5-[(3R,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]pentanoic acid
Show/Hide
|
C24H34O6
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0862926
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-4-phenoxy-1-buten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C22H25NO5S
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0847322
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-5-phenoxy-1-penten-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C23H27NO5S
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0414303
|
5-[(3S,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]pentanoic acid
Show/Hide
|
C24H34O6
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0446135
|
3-[(3S,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]propanoic acid
Show/Hide
|
C22H30O6
|
1
|
| 1 |
EC50 = 870 nM
|
|
|
|
CP0847320
|
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(2-phenoxyethyl)octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H23NO5S
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0432223
|
3-[(5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5,5a,6,7,8,8a-hexahydro-2H-cyclopenta[b]oxepin-3-yl]propanoic acid
Show/Hide
|
C22H28O6
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0387603
|
2-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H22N2O4S2
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0432213
|
CHEBI:60782
Show/Hide
|
C23H29F3O6
|
1
|
| 1 |
EC50 = 3400 nM
|
|
|
|
CP0414304
|
4-[(5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5,5a,6,7,8,8a-hexahydro-2H-cyclopenta[b]oxepin-3-yl]butanoic acid
Show/Hide
|
C23H30O6
|
1
|
| 1 |
EC50 = 4700 nM
|
|
|
|
CP0377468
|
3-[(3R,5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-3,4,5,5a,6,7,8,8a-octahydro-2H-cyclopenta[b]oxepin-3-yl]propanoic acid
Show/Hide
|
C22H30O6
|
1
|
| 1 |
EC50 = 4800 nM
|
|
|
|
CP0870958
|
2-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-(3-phenoxypropyl)octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H25NO5S
|
1
|
| 1 |
EC50 = 5800 nM
|
|
|
|
CP0398631
|
6-[(5aR,6R,7R,8aS)-7-hydroxy-6-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5,5a,6,7,8,8a-hexahydro-2H-cyclopenta[b]oxepin-3-yl]hexanoic acid
Show/Hide
|
C25H34O6
|
1
|
| 1 |
EC50 = 6400 nM
|
|
|
|
CP0847318
|
2-{(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(1E)-3-phenoxy-1-propen-1-yl]octahydrocyclopenta[b]pyran-2-yl}-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H23NO5S
|
1
|
| 1 |
EC50 = 7600 nM
|
|
|
|
CP0432222
|
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid
Show/Hide
|
C23H32O5
|
1
|
| 1 |
EC50 = 8600 nM
|
|
|
|
CP0391092
|
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-oxazole-4-carboxylic acid
Show/Hide
|
C20H22ClNO6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0391098
|
4-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]thiophene-2-carboxylic acid
Show/Hide
|
C21H23ClO5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0401698
|
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-methoxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C21H24ClNO5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0401699
|
2-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H22ClNO5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0401700
|
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H22ClNO5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0401702
|
2-[(2R,4aR,5S,6S,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-fluoro-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C20H21ClFNO4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0407410
|
4-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]furan-2-carboxylic acid
Show/Hide
|
C21H23ClO6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0434444
|
5-[(2R,4aR,5S,6R,7aS)-5-[(4-chloro-3-methylphenoxy)methyl]-6-hydroxy-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]furan-2-carboxylic acid
Show/Hide
|
C21H23ClO6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0380278
|
2-[(2R,4aR,5S,6R,7aS)-6-hydroxy-5-(phenoxymethyl)-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]-1,3-thiazole-4-carboxylic acid
Show/Hide
|
C19H21NO5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0926294
|
2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-isopropyl-3-methyl-butanamide
Show/Hide
|
C23H25FN2O2
|
2
|
| 1 |
IC50 = 1.5 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
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CP0953685
|
6-(8-fluoro-2-naphthyl)-3-[(1S)-2-methyl-1-[[(3S)-2-oxopyrrolidin-3-yl]methyl]propyl]-1H-pyridin-2-one
Show/Hide
|
C24H25FN2O2
|
2
|
| 1 |
IC50 = 1.8 nM
|
|
|
| 2 |
Ki = 1 nM
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|
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CP0963582
|
2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-N-(1-methylsulfonyl-4-piperidyl)butanamide
Show/Hide
|
C26H30FN3O4S
|
2
|
| 1 |
IC50 = 2.2 nM
|
|
|
| 2 |
Ki = 2 nM
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|
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CP0911039
|
2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-N-tetrahydropyran-4-yl-butanamide
Show/Hide
|
C25H27FN2O3
|
2
|
| 1 |
IC50 = 3.2 nM
|
|
|
| 2 |
Ki = 2.4 nM
|
|
|
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CP0926328
|
N-(1,1-dioxothian-4-yl)-2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-butanamide
Show/Hide
|
C25H27FN2O4S
|
2
|
| 1 |
IC50 = 5.9 nM
|
|
|
| 2 |
Ki = 2.6 nM
|
|
|
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CP0953595
|
2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-N-(1-methylbenzimidazol-5-yl)butanamide
Show/Hide
|
C28H25FN4O2
|
2
|
| 1 |
IC50 = 6.3 nM
|
|
|
| 2 |
Ki = 3.6 nM
|
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CP0928198
|
(Z)-5-(2-cyclopentyl-2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)ethylidene)oxazolidine-2,4-dione
Show/Hide
|
C25H21FN2O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0871062
|
(Z)-5-(2-cyclohexyl-2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)ethylidene)oxazolidine-2,4-dione
Show/Hide
|
C26H23FN2O4
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0926331
|
6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-[(Z)-(2-oxopyrrolidin-3-ylidene)methyl]propyl]-1H-pyridin-2-one
Show/Hide
|
C24H23FN2O2
|
2
|
| 1 |
IC50 = 8.1 nM
|
|
|
| 2 |
Ki = 5.3 nM
|
|
|
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CP0957032
|
6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-[(E)-(2-oxopyrrolidin-3-ylidene)methyl]propyl]-1H-pyridin-2-one
Show/Hide
|
C24H23FN2O2
|
2
|
| 1 |
IC50 = 8.7 nM
|
|
|
| 2 |
Ki = 2.2 nM
|
|
|
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CP0871063
|
(Z,S)-5-(2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)oxazolidine-2,4-dione
Show/Hide
|
C23H19FN2O4
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0966323
|
syn-6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutyl)thiazolidine-2,4-dione
Show/Hide
|
C23H21FN2O3S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0953684
|
2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-methoxy-3-methyl-butanamide
Show/Hide
|
C21H21FN2O3
|
2
|
| 1 |
IC50 = 9.7 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
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CP0964594
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(Z,R)-5-(2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)oxazolidine-2,4-dione
Show/Hide
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C23H19FN2O4
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1
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| 1 |
IC50 = 10 nM
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CP0953683
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(thiazol-2-ylamino)propyl]-1H-pyridin-2-one
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C22H20FN3OS
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2
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| 1 |
IC50 = 10 nM
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| 2 |
Ki = 9.4 nM
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CP0943549
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(Z)-5-(2-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)-1-methylimidazolidine-2,4-dione
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C24H22FN3O3
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1
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| 1 |
IC50 = 11 nM
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CP0947526
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-[(2-oxo-1-piperidyl)methyl]propyl]-1H-pyridin-2-one
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C25H27FN2O2
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2
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| 1 |
IC50 = 11 nM
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| 2 |
Ki = 2.5 nM
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CP0911037
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2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]-3-methyl-butanamide
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C27H33FN2O5
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2
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| 1 |
IC50 = 12 nM
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| 2 |
Ki = 5 nM
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CP0953582
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(morpholinomethyl)propyl]-1H-pyridin-2-one
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C24H27FN2O2
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2
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| 1 |
IC50 = 14 nM
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| 2 |
Ki = 4.1 nM
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CP0958536
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anti-3-(1-(1H-imidazol-2-yl)-2-methylpropyl)-6-(8-fluoronaphthalen-2-yl)pyridin-2(1H)-one
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C23H21FN2O4
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1
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| 1 |
IC50 = 15 nM
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CP0911036
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3-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-isopropyl-4-methyl-pentanamide
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C24H27FN2O2
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2
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| 1 |
IC50 = 15 nM
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| 2 |
Ki = 5.8 nM
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CP0869878
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anti-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutyl)thiazolidine-2,4-dione
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C23H21FN2O3S
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1
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| 1 |
IC50 = 17 nM
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CP0911031
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(4H-1,2,4-triazol-3-ylmethyl)propyl]-1H-pyridin-2-one
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C22H21FN4O
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2
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| 1 |
IC50 = 17 nM
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| 2 |
Ki = 10 nM
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CP0959579
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(Z)-5-(2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)oxazolidine-2,4-dione
Show/Hide
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C23H19FN2O4
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1
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| 1 |
IC50 = 21 nM
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CP0960239
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(4H-1,2,4-triazol-3-yl)propyl]-1H-pyridin-2-one
Show/Hide
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C21H19FN4O
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2
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| 1 |
IC50 = 21 nM
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| 2 |
Ki = 12 nM
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CP0958537
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(Z)-5-(3-Ethyl-2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)pentylidene)oxazolidine-2,4-dione
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C25H23FN2O4
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1
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| 1 |
IC50 = 23 nM
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CP0960240
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2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-(2-hydroxyethyl)-3-methyl-butanamide
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C22H23FN2O3
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2
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| 1 |
IC50 = 23 nM
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| 2 |
Ki = 3.7 nM
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CP0965351
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2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-N-(4-pyridyl)butanamide
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C25H22FN3O2
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2
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| 1 |
IC50 = 24 nM
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| 2 |
Ki = 5.7 nM
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CP0898452
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(Z)-5-(2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)thiazolidine-2,4-dione
Show/Hide
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C23H19FN2O3S
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1
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| 1 |
IC50 = 27 nM
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CP0928197
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syn-3-(1-(1H-imidazol-2-yl)-2-methylpropyl)-6-(8-fluoronaphthalen-2-yl)pyridin-2(1H)-one
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C23H21FN2O4
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1
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| 1 |
IC50 = 27 nM
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CP0911042
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(2-oxoimidazolidin-1-yl)propyl]-1H-pyridin-2-one
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C22H22FN3O2
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2
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| 1 |
IC50 = 28 nM
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| 2 |
Ki = 9.1 nM
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CP0561451
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6-(1-ethyl-4-fluoroindazol-6-yl)-3-[3-(1H-1,2,4-triazol-5-yl)pentan-3-yl]-1H-pyridin-2-one
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C21H23FN6O
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2
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| 1 |
IC50 = 29 nM
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| 2 |
Ki = 17 nM
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CP0957900
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5-(2-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutyl)imidazolidine-2,4-dione
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C23H22FN3O3
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1
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| 1 |
IC50 = 31 nM
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CP0556955
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(5Z)-5-[2-ethyl-2-[6-(1-ethyl-4-fluoroindazol-6-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
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C23H23FN4O4
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1
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| 1 |
IC50 = 33 nM
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CP0959429
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(Z)-5-(2-cyclopropyl-2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)ethylidene)oxazolidine-2,4-dione
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C23H17FN2O4
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1
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| 1 |
IC50 = 33 nM
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CP0911030
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6-(8-fluoro-2-naphthyl)-3-[1-(1H-imidazol-2-yl)-2-methyl-propyl]-1H-pyridin-2-one
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C22H20FN3O
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2
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| 1 |
IC50 = 33 nM
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| 2 |
Ki = 7.3 nM
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CP0558942
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6-(8-fluoronaphthalen-2-yl)-3-[3-(1H-1,2,4-triazol-5-yl)pentan-3-yl]-1H-pyridin-2-one
Show/Hide
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C22H21FN4O
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2
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| 1 |
IC50 = 36 nM
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| 2 |
Ki = 19 nM
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CP0953583
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(4-methyl-1H-imidazol-2-yl)propyl]-1H-pyridin-2-one
Show/Hide
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C23H22FN3O
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2
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| 1 |
IC50 = 36 nM
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| 2 |
Ki = 12 nM
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CP0926330
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(E)-[1-[1-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-2-methyl-propyl]imidazolidin-2-ylidene]cyanamide
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C23H22FN5O
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2
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| 1 |
IC50 = 38 nM
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| 2 |
Ki = 23 nM
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CP0966326
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(Z)-5-(3-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methylpentan-2-ylidene)oxazolidine-2,4-dione
Show/Hide
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C24H21FN2O4
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1
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| 1 |
IC50 = 39 nM
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CP0955739
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3-[1-(2-aminothiazol-5-yl)-2-methyl-propyl]-6-(8-fluoro-2-naphthyl)-1H-pyridin-2-one
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C22H20FN3OS
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2
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| 1 |
IC50 = 39 nM
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| 2 |
Ki = 16 nM
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CP0956167
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(2-oxo-1-piperidyl)propyl]-1H-pyridin-2-one
Show/Hide
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C24H25FN2O2
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2
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| 1 |
IC50 = 40 nM
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| 2 |
Ki = 6.4 nM
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CP0926335
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2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-3-methyl-butanamide
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C23H25FN2O4
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2
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| 1 |
IC50 = 41 nM
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| 2 |
Ki = 10 nM
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CP0947528
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3-[1-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-2-methyl-propyl]-4H-1,2,4-oxadiazol-5-one
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C21H18FN3O3
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2
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| 1 |
IC50 = 41 nM
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| 2 |
Ki = 15 nM
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CP0568404
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(5Z)-5-[2-[6-(6,8-difluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-2-ethylbutylidene]-1,3-oxazolidine-2,4-dione
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C24H20F2N2O4
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1
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| 1 |
IC50 = 45 nM
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CP0926292
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3-[1-(4,5-dimethyl-1H-imidazol-2-yl)-2-methyl-propyl]-6-(8-fluoro-2-naphthyl)-1H-pyridin-2-one
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C24H24FN3O
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2
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| 1 |
IC50 = 50 nM
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| 2 |
Ki = 7 nM
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CP0926327
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3-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-4-methyl-pentanamide
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C21H21FN2O2
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2
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| 1 |
IC50 = 53 nM
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| 2 |
Ki = 5 nM
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CP0563799
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(5Z)-5-[[1-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]cyclopropyl]methylidene]-1,3-oxazolidine-2,4-dione
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C22H15FN2O4
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1
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| 1 |
IC50 = 55 nM
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CP0571745
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(5Z)-5-[2-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-2-methylpropylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
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C22H17FN2O4
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1
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| 1 |
IC50 = 57 nM
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CP0558212
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(5Z)-5-[2-ethyl-2-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
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C24H21FN2O4
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1
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| 1 |
IC50 = 61 nM
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CP0563796
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(5Z)-5-[1-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-2-methylpropylidene]-1,3-thiazolidine-2,4-dione
Show/Hide
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C22H17FN2O3S
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1
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| 1 |
IC50 = 63 nM
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CP0958893
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6-(8-fluoro-2-naphthyl)-3-(2-methyl-1-oxazol-2-yl-propyl)-1H-pyridin-2-one
Show/Hide
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C22H19FN2O2
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2
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| 1 |
IC50 = 64 nM
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| 2 |
Ki = 24 nM
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CP0955090
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5-(2-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutyl)-1-methylimidazo-lidine-2,4-dione
Show/Hide
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C24H24FN3O3
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1
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| 1 |
IC50 = 65 nM
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CP0516972
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(5Z)-5-[[1-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]cyclopentyl]methylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
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C24H19FN2O4
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1
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| 1 |
IC50 = 66 nM
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CP0911040
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2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-N-thiazol-2-yl-butanamide
Show/Hide
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C23H20FN3O2S
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2
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| 1 |
IC50 = 67 nM
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| 2 |
Ki = 28 nM
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CP0073581
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5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
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C21H18N2O4
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2
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| 1 |
IC50 = 68 nM
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| 2 |
Ki = 10 nM
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CP0926329
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3-[1-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-2-methyl-propyl]-6-(8-fluoro-2-naphthyl)-1H-pyridin-2-one
Show/Hide
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C24H27FN2O3S
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2
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| 1 |
IC50 = 68 nM
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| 2 |
Ki = 8.8 nM
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CP0911032
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3-[2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-butyl]-4H-1,2,4-oxadiazol-5-one
Show/Hide
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C22H20FN3O3
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2
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| 1 |
IC50 = 70 nM
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| 2 |
Ki = 34 nM
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CP0960238
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6-(8-fluoro-2-naphthyl)-3-[1-(1H-imidazol-2-ylmethyl)-2-methyl-propyl]-1H-pyridin-2-one
Show/Hide
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C23H22FN3O
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2
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| 1 |
IC50 = 76 nM
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| 2 |
Ki = 11 nM
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CP0957899
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(Z)-5-(2-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)imidazolidine-2,4-dione
Show/Hide
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C23H20FN3O3
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1
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| 1 |
IC50 = 87 nM
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CP0543351
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6-(1-ethyl-4-fluoroindazol-6-yl)-3-[3-(5-methyl-1H-1,2,4-triazol-3-yl)pentan-3-yl]-1H-pyridin-2-one
Show/Hide
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C22H25FN6O
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2
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| 1 |
IC50 = 90 nM
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| 2 |
Ki = 34 nM
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CP0556954
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(5Z)-5-[2-ethyl-2-[6-(8-ethylnaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
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C26H26N2O4
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1
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| 1 |
IC50 = 91 nM
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CP0966319
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syn-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-2-methylpropyl)oxazolidine-2,4-dione
Show/Hide
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C22H19FN2O4
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1
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| 1 |
IC50 = 92 nM
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CP0966325
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(Z)-5-(2-(6-(8-Fluoronaphthalen-2-yl)-5-methyl-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)oxazolidine-2,4-dione
Show/Hide
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C24H21FN2O4
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1
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| 1 |
IC50 = 92 nM
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CP0548382
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6-(1-ethyl-4-fluoroindazol-6-yl)-3-[3-(1-methyl-1,2,4-triazol-3-yl)pentan-3-yl]-1H-pyridin-2-one
Show/Hide
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C22H25FN6O
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2
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| 1 |
IC50 = 96 nM
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| 2 |
Ki = 39 nM
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CP0960241
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2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-3-methyl-butanamide
Show/Hide
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C24H27FN2O5
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2
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| 1 |
IC50 = 99 nM
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| 2 |
Ki = 25 nM
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CP0966322
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5-(1-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-2-methylpropyl)thiazolidine-2,4-dione
Show/Hide
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C22H19FN2O3S
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1
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| 1 |
IC50 = 110 nM
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CP0485538
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6-(1-ethyl-4-fluoroindazol-6-yl)-3-[3-(4-methyl-1,2,4-triazol-3-yl)pentan-3-yl]-1H-pyridin-2-one
Show/Hide
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C22H25FN6O
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2
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| 1 |
IC50 = 120 nM
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| 2 |
Ki = 54 nM
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CP0911041
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-[(4-methylsulfonylpiperazin-1-yl)methyl]propyl]-1H-pyridin-2-one
Show/Hide
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C25H30FN3O3S
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2
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| 1 |
IC50 = 120 nM
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| 2 |
Ki = 15 nM
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CP0926336
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3-[1-(1,1-dioxothiazinan-2-yl)-2-methyl-propyl]-6-(8-fluoro-2-naphthyl)-1H-pyridin-2-one
Show/Hide
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C23H25FN2O3S
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2
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| 1 |
IC50 = 122 nM
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| 2 |
Ki = 14 nM
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CP0953687
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(1H-tetrazol-5-ylmethyl)propyl]-1H-pyridin-2-one
Show/Hide
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C21H20FN5O
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2
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| 1 |
IC50 = 134 nM
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| 2 |
Ki = 34 nM
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CP0966838
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6-(8-fluoro-2-naphthyl)-3-[2-methyl-1-(4H-1,2,4-triazol-3-ylamino)propyl]-1H-pyridin-2-one
Show/Hide
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C21H20FN5O
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2
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| 1 |
IC50 = 185 nM
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| 2 |
Ki = 22 nM
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CP0955091
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(Z)-5-(2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-2,3-dihydropyridin-3-yl)-2-phenylethylidene)oxazolidine-2,4-dione
Show/Hide
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C26H17FN2O4
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1
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| 1 |
IC50 = 190 nM
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CP0957043
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3-methyl-2-[6-(2-naphthyl)-2-oxo-1H-pyridin-3-yl]butanamide
Show/Hide
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C20H20N2O2
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2
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| 1 |
IC50 = 191 nM
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| 2 |
Ki = 18 nM
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CP0898410
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(Z)-5-(2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-phenylpropylidene)oxazolidine-2,4-dione
Show/Hide
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C27H19FN2O4
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1
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| 1 |
IC50 = 200 nM
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CP0561450
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6-(4-ethyl-8-fluoro-2,3-dihydro-1,4-benzoxazin-6-yl)-3-[3-(1H-1,2,4-triazol-5-yl)pentan-3-yl]-1H-pyridin-2-one
Show/Hide
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C22H26FN5O2
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2
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| 1 |
IC50 = 200 nM
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| 2 |
Ki = 97 nM
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CP0558213
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(5Z)-5-[2-ethyl-2-[6-(4-ethyl-2,3-dihydro-1,4-benzoxazin-6-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
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C24H27N3O5
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1
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| 1 |
IC50 = 220 nM
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CP0871082
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5-(1-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-2-methylpropyl)imidazolidine-2,4-dione
Show/Hide
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C22H20FN3O3
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1
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| 1 |
IC50 = 320 nM
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CP0966321
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5-(1-(6-(8-Fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-2-methylpropyl)-1-methylimidazolidine-2,4-dione
Show/Hide
|
C23H22FN3O3
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0095751
|
(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid
Show/Hide
|
C20H34O5
|
1
|
| 1 |
IC50 = 322 nM
|
|
|
|
CP0911029
|
N-(azetidin-3-yl)-2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-butanamide
Show/Hide
|
C23H24FN3O2
|
2
|
| 1 |
IC50 = 347 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0546226
|
(5Z)-5-[1-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-2-methylpropylidene]-1-methylimidazolidine-2,4-dione
Show/Hide
|
C23H20FN3O3
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0514831
|
6-(6,8-difluoronaphthalen-2-yl)-3-[3-(1H-1,2,4-triazol-5-yl)pentan-3-yl]-1H-pyridin-2-one
Show/Hide
|
C22H20F2N4O
|
2
|
| 1 |
IC50 = 350 nM
|
|
|
| 2 |
Ki = 89 nM
|
|
|
|
CP0966324
|
(Z)-5-(2-(5-chloro-6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutylidene)oxazolidine-2,4-dione
Show/Hide
|
C23H18ClFN2O4
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0911035
|
2-fluoro-2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-3-methyl-butanamide
Show/Hide
|
C20H18F2N2O2
|
2
|
| 1 |
IC50 = 426 nM
|
|
|
| 2 |
Ki = 26 nM
|
|
|
|
CP0922698
|
N-(2-(dimethylamino)ethyl)-2-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-3-methylbutanamide
Show/Hide
|
C24H28FN3O2
|
2
|
| 1 |
IC50 = 445 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0926293
|
2-hydroxy-3-methyl-2-[6-(2-naphthyl)-2-oxo-1H-pyridin-3-yl]butanamide
Show/Hide
|
C20H20N2O3
|
2
|
| 1 |
IC50 = 509 nM
|
|
|
| 2 |
Ki = 50 nM
|
|
|
|
CP0966320
|
anti-(6-(8-fluoronaphthalen-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)-2-methylpropyl)oxazolidine
Show/Hide
|
C22H19FN2O4
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0295469
|
(Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid
Show/Hide
|
C22H29ClO6
|
1
|
| 1 |
IC50 = 635 nM
|
|
|
|
CP0572991
|
(4E)-4-[1-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-2-methylpropylidene]-1,3-oxazolidine-2,5-dione
Show/Hide
|
C22H17FN2O4
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0445340
|
7-{3,5-Dihydroxy-2-[3-hydroxy-4-(thiophen-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid
Show/Hide
|
C20H32O5S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0571744
|
(5Z)-5-[1-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-2-methylpropylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
|
C22H17FN2O4
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0922699
|
2-hydroxy-3-methyl-2-[6-(2-naphthyl)-2-oxo-1H-pyridin-3-yl]butanoic acid
Show/Hide
|
C20H19NO4
|
2
|
| 1 |
IC50 = 1580 nM
|
|
|
| 2 |
Ki = 544 nM
|
|
|
|
CP0477510
|
4-[(1S)-1-[[5-prop-1-ynyl-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C23H19F3N4O3
|
1
|
| 1 |
IC50 = 2292.3 nM
|
|
|
|
CP0402541
|
7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
Show/Hide
|
C22H33ClO6
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0438269
|
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyclopentyl]-heptanoic acid
Show/Hide
|
C22H34O6
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0372737
|
7-[3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acid
Show/Hide
|
C23H36O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0374214
|
7-{2-[4-(3-Chloro-phenylsulfanyl)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
Show/Hide
|
C22H33ClO5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0377752
|
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenylamino-butyl)-cyclopentyl]-heptanoic acid
Show/Hide
|
C22H35NO5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0395236
|
7-{2-[4-(3-Fluoro-phenylsulfanyl)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
Show/Hide
|
C22H33FO5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0402565
|
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-phenyl-pentyl)-cyclopentyl]-heptanoic acid
Show/Hide
|
C23H36O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0432809
|
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-octyl)-cyclopentyl]-heptanoic acid
Show/Hide
|
C20H38O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0432810
|
7-{3,5-Dihydroxy-2-[3-hydroxy-4-(thiazol-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid
Show/Hide
|
C19H31NO5S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0433187
|
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acid
Show/Hide
|
C22H34O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0448266
|
7-{3,5-Dihydroxy-2-[3-hydroxy-4-(3-trifluoromethyl-phenylsulfanyl)-butyl]-cyclopentyl}-heptanoic acid
Show/Hide
|
C23H33F3O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0427396
|
4-[(1S)-1-[[5-phenyl-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C26H21F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0427397
|
4-[(1S)-1-[[5-(cyclopenten-1-yl)-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C25H23F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435681
|
US8686018, 107
Show/Hide
|
C22H18F5N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0438577
|
4-[(1S)-1-[[5-phenyl-3-[2-[3-(trifluoromethyl)phenoxy]ethyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C27H23F3N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0438580
|
4-[(1S)-1-[[5-(furan-3-yl)-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C24H19F3N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0473341
|
4-[(1S)-1-[[5-(5-methylthiophen-2-yl)-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C25H21F3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0473342
|
4-[(1S)-1-[[5-thiophen-3-yl-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C24H19F3N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0473344
|
4-[(1S)-1-[[5-[(E)-prop-1-enyl]-3-[[4-(trifluoromethyl)phenyl]methyl]triazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C23H21F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0477511
|
4-[(1S)-1-[[3-[2-(4-fluorophenoxy)ethyl]-5-phenyltriazole-4-carbonyl]amino]ethyl]benzoic acid
Show/Hide
|
C26H23FN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0571749
|
(5Z)-5-[2-ethyl-2-[6-(1-ethyl-3-methylindazol-6-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0556956
|
(5Z)-5-[2-ethyl-2-[6-(2-ethyl-4-fluoroindazol-5-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
|
C23H23FN4O4
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0571750
|
(5Z)-5-[2-ethyl-2-[6-(1-ethyl-4-fluoroindazol-5-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
|
C23H23FN4O4
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0572992
|
(5Z)-5-[2-[6-(2,2-dimethyl-3,4-dihydrochromen-7-yl)-2-oxo-1H-pyridin-3-yl]-2-ethylbutylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
|
C25H28N2O5
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0578917
|
(5Z)-5-[2-ethyl-2-[6-(1-ethyl-5-methylindazol-6-yl)-2-oxo-1H-pyridin-3-yl]butylidene]-1,3-oxazolidine-2,4-dione
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0966018
|
(R)-6-(1-ethyl-4-methyl-1H-indazol-6-yl)-3-(3-methyl-2-oxopyrrolidin-3-yl)pyridin-2(1H)-one
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0520913
|
5-(5-methyl-6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C22H20N2O4
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0911043
|
6-(8-fluoro-2-naphthyl)-3-[(1R)-2-methyl-1-[[(3S)-2-oxopyrrolidin-3-yl]methyl]propyl]-1H-pyridin-2-one
Show/Hide
|
C24H25FN2O2
|
1
|
| 1 |
Ki = 7.1 nM
|
|
|
|
CP0495383
|
(5S)-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H18N2O4
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0498674
|
5-cyclopentyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C23H20N2O4
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0528861
|
5-cyclohexyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C24H22N2O4
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0437974
|
5-benzyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C25H18N2O4
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0488369
|
5-methyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C19H14N2O4
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0520924
|
(5R)-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H18N2O4
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0500008
|
5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-phenyl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C24H16N2O4
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0422124
|
5-(5-bromo-6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H17BrN2O4
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0501496
|
3-(4-methyl-2-oxoimidazolidin-4-yl)-6-naphthalen-2-yl-1H-pyridin-2-one
Show/Hide
|
C19H17N3O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0425897
|
5-cyclopropyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H16N2O4
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0528843
|
5-(5-chloro-6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H17ClN2O4
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0437977
|
5-methyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidin-2-one
Show/Hide
|
C19H16N2O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0503174
|
5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-(trifluoromethyl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C19H11F3N2O4
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0437976
|
5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-(oxan-4-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C23H20N2O5
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0513984
|
5-methyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)imidazolidine-2,4-dione
Show/Hide
|
C19H15N3O3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0383448
|
5-[2-[5-chloro-2-[(4-fluorophenyl)methoxy]phenyl]-5-methylpyrrol-1-yl]-2-methylbenzoic acid
Show/Hide
|
C26H21ClFNO3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0209434
|
3-acetamido-5-[2-[5-bromo-2-[(2,4-difluorophenyl)methoxy]phenyl]-5-methylpyrrol-1-yl]benzoic acid
Show/Hide
|
C27H21BrF2N2O4
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0377854
|
3,5-dimethyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C20H16N2O4
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0377857
|
5-[6-naphthalen-2-yl-2-oxo-5-(trifluoromethyl)-1H-pyridin-3-yl]-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C22H17F3N2O4
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0531249
|
5-(6-naphthalen-2-yl-4-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H18N2O4
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0501497
|
5-(2-hydroxy-4-naphthalen-2-ylphenyl)-5-methyl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C20H15NO4
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0555218
|
5-methyl-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-3-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C22H20N2O4
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0555219
|
5-(6-naphthalen-2-yl-2-oxo-5-phenyl-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C27H22N2O4
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0460683
|
5-(2-methoxy-4-naphthalen-2-ylphenyl)-5-methyl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H17NO4
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0377855
|
5-methyl-5-(1-methyl-6-naphthalen-2-yl-2-oxopyridin-3-yl)-1,3-oxazolidine-2,4-dione
Show/Hide
|
C20H16N2O4
|
1
|
| 1 |
Ki > 25118.86 nM
|
|
|
|
CP0504278
|
5-(6-naphthalen-2-ylpyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Show/Hide
|
C21H18N2O3
|
1
|
| 1 |
Ki > 25118.86 nM
|
|
|
