Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(6,8-difluoronaphthalen-2-yl)-3-[3-(1H-1,2,4-triazol-5-yl)pentan-3-yl]-1H-pyridin-2-one
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 PubChem ID
CID: 137478291
Canonical SMILES
CCC(CC)(c1nnc[nH]1)c1ccc([nH]c1=O)-c1ccc2cc(F)cc(F)c2c1
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Compound Formula C22H20F2N4O
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
2
Ki = 89 nM
   TI
   LI
   LO
   TS