Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-6-(1-ethyl-4-methyl-1H-indazol-6-yl)-3-(3-methyl-2-oxopyrrolidin-3-yl)pyridin-2(1H)-one
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 PubChem ID
CID: 117993349
Canonical SMILES
CCn1ncc2c(C)cc(-c3ccc([C@@]4(C)CCNC4=O)c(=O)[nH]3)cc21
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Compound Formula C20H22N4O2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 31.6 nM