Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(4-ethyl-8-fluoro-2,3-dihydro-1,4-benzoxazin-6-yl)-3-[3-(1H-1,2,4-triazol-5-yl)pentan-3-yl]-1H-pyridin-2-one
    Show/Hide
 PubChem ID
CID: 137477592
Canonical SMILES
CCN1CCOc2c(F)cc(cc12)-c1ccc(c(=O)[nH]1)C(CC)(CC)c1nnc[nH]1
    Show/Hide
Compound Formula C22H26FN5O2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
2
Ki = 97 nM
   TI
   LI
   LO
   TS