Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(1-ethyl-4-fluoroindazol-6-yl)-3-[3-(1-methyl-1,2,4-triazol-3-yl)pentan-3-yl]-1H-pyridin-2-one
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 PubChem ID
CID: 137477947
Canonical SMILES
CCn1ncc2c(F)cc(cc12)-c1ccc(c(=O)[nH]1)C(CC)(CC)c1ncn(C)n1
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Compound Formula C22H25FN6O
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 96 nM
   TI
   LI
   LO
   TS
2
Ki = 39 nM
   TI
   LI
   LO
   TS