Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[6-(8-fluoro-2-naphthyl)-2-oxo-1H-pyridin-3-yl]-N-methoxy-3-methyl-butanamide
    Show/Hide
 PubChem ID
CID: 137477644
Canonical SMILES
CONC(=O)C(c1ccc(-c2ccc3cccc(F)c3c2)[nH]c1=O)C(C)C
    Show/Hide
Compound Formula C21H21FN2O3
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 9.7 nM
   TI
   LI
   LO
   TS
2
Ki = 2.9 nM
   TI
   LI
   LO
   TS